Physiology and Molecular Biology of Plants, Год журнала: 2025, Номер 31(2), С. 199 - 209
Опубликована: Фев. 1, 2025
Язык: Английский
The Plant Cell, Год журнала: 2024, Номер 36(5), С. 1451 - 1464
Опубликована: Янв. 2, 2024
As the most widely used herbal medicine in human history and a major defence hormone plants against broad spectrum of pathogens abiotic stresses, salicylic acid (SA) has attracted research interest. With applications modern technologies over past 30 years, studies effects SA on plant growth, development, have revealed many new frontiers continue to deliver surprises. In this review, we provide an update recent advances our understanding metabolism, perception, signal transduction mechanisms immunity. An overarching theme emerges that executes its functions through intricate regulation at multiple steps: biosynthesis is regulated both locally systemically, while perception occurs cellular targets, including metabolic enzymes, redox regulators, transcription cofactors, and, recently, RNA-binding protein. Moreover, orchestrates complex series post-translational modifications downstream signaling components promotes formation biomolecular condensates function as signalling hubs. also impacts wider crosstalk with other hormones. Looking into future, propose areas for exploration functions, which will undoubtedly uncover more surprises years come.
Язык: Английский
Процитировано
50
Cell Host & Microbe, Год журнала: 2023, Номер 31(10), С. 1732 - 1747.e5
Опубликована: Сен. 22, 2023
Pathogen infection is a dynamic process. Here, we employ single-cell transcriptomics to investigate plant response heterogeneity. By generating an Arabidopsis thaliana leaf atlas encompassing 95,040 cells during by fungal pathogen, Colletotrichum higginsianum, unveil cell-type-specific gene expression, notably enrichment of intracellular immune receptors in vasculature cells. Trajectory inference identifies that had different interactions with the invading fungus. This analysis divulges transcriptional reprogramming abscisic acid signaling specifically occurring guard cells, which consistent stomatal closure dependent on direct contact Furthermore, plasticity genes involved glucosinolate biosynthesis at sites, emphasizing contribution epidermis-expressed MYB122 disease resistance. work underscores spatially dynamic, responses pathogen and provides valuable resource supports in-depth investigations plant-pathogen interactions.
Язык: Английский
Процитировано
42
The Plant Cell, Год журнала: 2024, Номер 36(5), С. 1465 - 1481
Опубликована: Янв. 23, 2024
Abstract Plant diseases are a constant and serious threat to agriculture ecological biodiversity. Plants possess sophisticated innate immunity system capable of detecting responding pathogen infection prevent disease. Our understanding this has grown enormously over the past century. Early genetic descriptions plant disease resistance virulence were embodied in gene-for-gene hypothesis, while physiological studies identified pathogen-derived elicitors that could trigger defense responses cells tissues. Molecular these phenomena have now coalesced into an integrated model involving cell surface intracellular detection specific molecules proteins culminating induction various cellular responses. Extracellular receptors engage distinct signaling processes but converge on many similar outputs with substantial evidence for integration pathways interdependent networks controlling outcomes. Many molecular details recognition known, providing opportunities bioengineering enhance protection from Here we provide overview current main principles immunity, emphasis key scientific milestones leading insights.
Язык: Английский
Процитировано
32
Trends in Plant Science, Год журнала: 2024, Номер 29(10), С. 1145 - 1155
Опубликована: Май 26, 2024
Язык: Английский
Процитировано
16
Nature, Год журнала: 2025, Номер unknown
Опубликована: Янв. 8, 2025
Abstract Plants lack specialized and mobile immune cells. Consequently, any cell type that encounters pathogens must mount responses communicate with surrounding cells for successful defence. However, the diversity, spatial organization function of cellular states in pathogen-infected plants are poorly understood 1 . Here we infect Arabidopsis thaliana leaves bacterial trigger or supress integrate time-resolved single-cell transcriptomic, epigenomic transcriptomic data to identify states. We describe cell-state-specific gene-regulatory logic involves transcription factors, putative cis -regulatory elements target genes associated disease immunity. show a rare population emerges at nexus immune-active hotspots, which designate as primary responder (PRIMER) PRIMER have non-canonical signatures, exemplified by expression genome accessibility previously uncharacterized factor, GT-3A, contributes plant immunity against pathogens. surrounded another state (bystander) activates long-distance cell-to-cell signalling. Together, our findings suggest interactions between these propagate across leaf. Our molecularly defined spatiotemporal atlas provides functional regulatory insights into plants.
Язык: Английский
Процитировано
2
Current Opinion in Plant Biology, Год журнала: 2023, Номер 75, С. 102432 - 102432
Опубликована: Июль 29, 2023
Priming reflects the capacity of plants to memorise environmental stress experience and improve their response recurring stress. Epigenetic modifications in DNA associated histone proteins may carry short-term long-term memory same plant or mediate transgenerational effects, but evidence is still largely circumstantial. New experimental tools now enable scientists perform targeted manipulations that either prevent generate a particular epigenetic modification location genome. Such 'reverse epigenetics' approaches allow for interrogation causality between individual priming-induced role altering gene expression performance under Furthermore, combining site-directed manipulation with conditional cell-type specific promoters creates novel opportunities test engineer spatiotemporal patterns priming.
Язык: Английский
Процитировано
35
New Crops, Год журнала: 2023, Номер 1, С. 100004 - 100004
Опубликована: Ноя. 18, 2023
Microbes accompany plants throughout their lives, from the seed to ripe fruit. Plant-microbe interactions have long been a focus of research, leading thousands articles that demonstrate importance for agriculture. Here, we review these previous findings, and discuss future directions prospects application plant-microbe various perspectives: community composition, pathways interaction, influencing factors interactions, methods techniques studying potential applications interactions. We propose exploiting utilizing core beneficial microbes, artificial assembly microbiota, in situ regulation microbiome function will all become essential aspects
Язык: Английский
Процитировано
29
Nature Plants, Год журнала: 2023, Номер 9(8), С. 1184 - 1190
Опубликована: Авг. 3, 2023
Язык: Английский
Процитировано
26
Communications Biology, Год журнала: 2023, Номер 6(1)
Опубликована: Авг. 4, 2023
Plants are in contact with diverse pathogens and microorganisms. Intense investigation over the last 30 years has resulted identification of multiple immune receptors model crop species as well signaling overlap surface-localized intracellular receptors. However, scientists still have a limited understanding how plants respond to spatial cellular resolution. Recent advancements single-cell, single-nucleus technologies can now be applied plant-pathogen interactions. Here, we outline current state these highlight outstanding biological questions that addressed future.
Язык: Английский
Процитировано
25
Nature Reviews Microbiology, Год журнала: 2024, Номер 22(6), С. 360 - 372
Опубликована: Янв. 8, 2024
Язык: Английский
Процитировано
15