Microplastics and human health: Integrating pharmacokinetics

Critical Reviews in Environmental Science and Technology, Год журнала: 2023, Номер 53(16), С. 1489 - 1511

Опубликована: Апрель 8, 2023

Microplastics are widespread contaminants leading to environmental exposure. While studies on the prevalence in human tissues have multiplied, little is known about their pharmacokinetics. Mechanisms of absorption, distribution, metabolism, and excretion (ADME) must be addressed before effects health (i.e. pharmacodynamics) can understood. Therefore, objective this review was provide an integrated assessment fate microplastics body by gathering information from multiple fields research (e.g. implants microspheres). Absorption mainly occurs through transcytosis enterocytes, while larger particles may internalized gaps persorption) or uptake phagocytes. Only <5 µm reach alveolar region, large found lungs usually result entrapment circulating narrow pulmonary capillary network. Overall, absorption rates expected low. then distributed circulatory system, accumulating respiratory digestive liver, spleen, brain. Metabolism lead biodegradation microplastics, enzymes reactive oxygen species macrophages, exposure physiologic fluids, microbiologic activity gut lumen. Finally, most will removed liver spleen excreted feces. work provides initial attempt at constructing a pharmacokinetics model for further required. Ideally, future works should conducted using histopathology techniques obtain precise location radiolabelled allow tracking time.

Язык: Английский

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A comprehensive review of micro- and nano-plastics in the atmosphere: Occurrence, fate, toxicity, and strategies for risk reduction

The Science of The Total Environment, Год журнала: 2023, Номер 904, С. 166649 - 166649

Опубликована: Сен. 1, 2023

Язык: Английский

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Microplastics alter soil structure and microbial community composition

Environment International, Год журнала: 2024, Номер 185, С. 108508 - 108508

Опубликована: Фев. 16, 2024

Microplastics (MPs), including conventional hard-to-biodegrade petroleum-based and faster biodegradable plant-based ones, impact soil structure microbiota in turn affecting the biodiversity functions of terrestrial ecosystems. Herein, we investigated effects MPs on aggregate distribution microbial community composition microhabitats at scale. Two MP types (polyethylene (PE) polylactic acid (PLA) with increasing size (50, 150, 300 μm)) were mixed a silty loam (0–20 cm) ratio 0.5 % (w/w) rice–wheat rotation system greenhouse under 25 °C for one year. The aggregation, bacterial communities their co-occurrence networks as function size. Conventional generally had similar aggregation communities. They increased proportion microaggregates from 17 to 32 while reducing macroaggregates 84 68 %. stability decreased 1.4 mm 1.0–1.1 independently due decline binding agents (e.g., byproducts proteinaceous substances). type amount strongly affected structure, accounting approximately 54 variance. Due less bioavailable organics, within was more sensitive addition. Co-occurrence network analysis revealed that exacerbated competition among bacteria complexity networks. Such stronger PE than PLA higher persistence soils. Proteobacteria, Bacteroidetes, Chloroflexi, Actinobacteria, Gemmatimonadetes keystone taxa macroaggregates, Actinobacteria Chloroflexi microaggregates. most Overall, both reduced portion large stable aggregates, altering structures taxa.

Язык: Английский

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Interaction of microplastics with heavy metals in soil: Mechanisms, influencing factors and biological effects

The Science of The Total Environment, Год журнала: 2024, Номер 918, С. 170281 - 170281

Опубликована: Янв. 24, 2024

Язык: Английский

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A comprehensive review on the source, ingestion route, attachment and toxicity of microplastics/nanoplastics in human systems

Journal of Environmental Management, Год журнала: 2024, Номер 352, С. 120039 - 120039

Опубликована: Янв. 13, 2024

Язык: Английский

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From organic fertilizer to the soils: What happens to the microplastics? A critical review

The Science of The Total Environment, Год журнала: 2024, Номер 919, С. 170217 - 170217

Опубликована: Фев. 1, 2024

Язык: Английский

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Microplastics in agricultural soils: A comprehensive perspective on occurrence, environmental behaviors and effects

Chemical Engineering Journal, Год журнала: 2024, Номер 489, С. 151328 - 151328

Опубликована: Апрель 16, 2024

Язык: Английский

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Assessing microplastic and nanoplastic contamination in bird lungs: evidence of ecological risks and bioindicator potential

Journal of Hazardous Materials, Год журнала: 2025, Номер 487, С. 137274 - 137274

Опубликована: Янв. 17, 2025

Язык: Английский

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Microplastics in soils: A comprehensive review

The Science of The Total Environment, Год журнала: 2025, Номер 960, С. 178298 - 178298

Опубликована: Янв. 1, 2025

Язык: Английский

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Specific response of soil properties to microplastics pollution: A review

Environmental Research, Год журнала: 2023, Номер 232, С. 116427 - 116427

Опубликована: Июнь 15, 2023

Язык: Английский

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