iScience,
Год журнала:
2023,
Номер
26(12), С. 108454 - 108454
Опубликована: Ноя. 14, 2023
Understanding
the
pathways
of
human
exposure
to
micro(nano)plastics
(MNPs)
is
crucial
for
assessing
their
health
impacts.
Intravenous
infusion
can
induce
MNPs
direct
entry
into
blood,
posing
serious
risks
on
health,
but
remains
unclear.
Herein,
we
developed
comprehensive
analytical
methods
detect
polyvinyl
chloride
(PVC)
down
20
nm,
and
found
about
0.52
μg
equal
105-1011
particles
PVC-MNPs
released
from
intravenous
products
(IVIPs)
during
each
250
mL
injection.
The
amounts
IVIPs
were
dependent
plastic
materials,
injection
volume
composition.
These
findings
indicated
that
should
be
directly
introduced
blood
circulatory
system,
causing
impacts
health.
Our
study
reveals
a
previously
ignored
important
pathway
MNPs,
calls
further
research
potential
these
Twenty
years
after
the
first
publication
that
used
term
microplastic,
we
review
current
understanding,
refine
definitions,
and
consider
future
prospects.
Microplastics
arise
from
multiple
sources,
including
tires,
textiles,
cosmetics,
paint,
fragmentation
of
larger
items.
They
are
widely
distributed
throughout
natural
environment,
with
evidence
harm
at
levels
biological
organization.
pervasive
in
food
drink
have
been
detected
human
body,
emerging
negative
effects.
Environmental
contamination
could
double
by
2040,
wide-scale
has
predicted.
Public
concern
is
increasing,
diverse
measures
to
address
microplastic
pollution
being
considered
international
negotiations.
Clear
on
efficacy
potential
solutions
now
needed
issue
minimize
risks
unintended
consequences.
EBioMedicine,
Год журнала:
2023,
Номер
99, С. 104901 - 104901
Опубликована: Дек. 6, 2023
Humans
are
exposed
to
micro-and-nano
plastics
(MNPs)
through
various
routes,
but
the
adverse
health
effects
of
MNPs
on
different
organ
systems
not
yet
fully
understood.
This
review
aims
provide
an
overview
potential
impacts
and
identify
knowledge
gaps
in
current
research.
The
summarized
results
suggest
that
exposure
can
lead
oxidative
stress,
inflammation,
immune
dysfunction,
altered
biochemical
energy
metabolism,
impaired
cell
proliferation,
disrupted
microbial
metabolic
pathways,
abnormal
development,
carcinogenicity.
There
is
limited
human
data
MNPs,
despite
evidence
from
animal
cellular
studies.
Most
published
research
has
focused
specific
types
assess
their
toxicity,
while
other
plastic
particles
commonly
found
environment
remain
unstudied.
Future
studies
should
investigate
by
considering
realistic
concentrations,
dose-dependent
effects,
individual
susceptibility,
confounding
factors.
Environmental Science & Technology,
Год журнала:
2024,
Номер
unknown
Опубликована: Фев. 5, 2024
The
increasing
global
attention
on
micro(nano)plastics
(MNPs)
is
a
result
of
their
ubiquity
in
the
water,
air,
soil,
and
biosphere,
exposing
humans
to
MNPs
daily
basis
threatening
human
health.
However,
crucial
data
body,
including
sources,
occurrences,
behaviors,
health
risks,
are
limited,
which
greatly
impedes
any
systematic
assessment
impact
body.
To
further
understand
effects
we
must
identify
existing
knowledge
gaps
that
need
be
immediately
addressed
provide
potential
solutions
these
issues.
Herein,
examined
current
literature
behaviors
body
as
well
risks.
Furthermore,
identified
key
resolved
comprehensively
assess
Additionally,
complexity
lack
efficient
analytical
methods
main
barriers
impeding
investigations
necessitating
development
standard
unified
method.
Finally,
highlighted
for
interdisciplinary
studies
from
environmental,
biological,
medical,
chemical,
computer,
material
scientists
fill
drive
research.
Considering
inevitability
occurrence
exposure
MNPs,
more
urgently
required
enhance
our
understanding
negative
Turkish Journal of Fisheries and Aquatic Sciences,
Год журнала:
2023,
Номер
23(12)
Опубликована: Ноя. 2, 2023
Aquatic
environments
are
one
of
the
final
destinations
for
microplastics.
In
this
review,
a
combination
systematic
and
narrative
literature
review
was
conducted
to
identify
summarise
advances,
gaps,
future
directions
in
microplastic
monitoring
studies
Turkish
aquatic
environment
inhabiting
organisms.
A
total
62
peer-reviewed
publications
available
on
Web
Science
were
considered
review.
Additionally,
current
state
pollution
which
includes
marine
freshwater
ecosystems,
as
well
organisms,
sources
characteristics
microplastics
reviewed
narratively.
Türkiye`s
position
global
plastic
treaty
mitigation
practices
also
addressed.
Although
an
increase
number
over
time
observed,
extent
carried
out
ecosystems
limited.
Strict
legislation
should
be
enacted
enforced
tackle
Türkiye.
nationwide,
long-term
at
sufficiently
regular
intervals
considered.
Animals,
Год журнала:
2024,
Номер
14(2), С. 350 - 350
Опубликована: Янв. 22, 2024
Plastic
pollution
is
a
global
diffuse
threat,
especially
considering
its
fragmentation
into
microplastics
(MPs)
and
nanoplastics
(NPs).
Since
the
contamination
of
aquatic
environment
already
well
studied,
most
studies
have
now
focused
on
soil.
Moreover,
number
exposure
routes
toxic
effects
MNPs
in
humans
continuously
increasing.
Although
can
cause
inflammation,
cytotoxicity,
genotoxicity
immune
toxicity
livestock
animals,
which
accumulate
ingested/inhaled
plastic
particles
transfer
them
to
through
food
chain,
research
this
topic
still
lacking.
In
farm
animals
as
missing
link
between
soil/plant
human
health
effects,
paper
aims
describe
their
importance
carriers
vectors
MNP
contamination.
As
early
stages,
there
no
standard
method
quantify
amount
characteristics
different
matrices.
Therefore,
creation
common
database
where
researchers
report
data
quantification
methods
could
be
helpful
for
both
standardization
future
training
an
AI
tool
predicting
abundant/dangerous
polymer(s),
thus
supporting
policy
decisions
reduce
perfectly
fitting
with
One
Health
principles.
