Design principles of food gels

Nature Food, Год журнала: 2020, Номер 1(2), С. 106 - 118

Опубликована: Фев. 18, 2020

Язык: Английский

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Advances in Antimicrobial Microneedle Patches for Combating Infections

Advanced Materials, Год журнала: 2020, Номер 32(33)

Опубликована: Июнь 29, 2020

Abstract Skin infections caused by bacteria, viruses and fungi are difficult to treat conventional topical administration because of poor drug penetration across the stratum corneum. This results in low bioavailability drugs infection site, as well lack prolonged release. Emerging antimicrobial transdermal ocular microneedle patches have become promising medical devices for delivery various antibacterial, antifungal, antiviral therapeutics. In present review, skin anatomy its barriers along with discussed. Potential strategies designing microneedles their targeted therapy outlined. Finally, biosensing associated personalized selective toxicity toward specific microbial species

Язык: Английский

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Encapsulation and delivery of bioactive compounds using spray and freeze-drying techniques: A review

Drying Technology, Год журнала: 2019, Номер 38(1-2), С. 235 - 258

Опубликована: Авг. 19, 2019

There are various bioactive components exist in plants, fruits, and vegetable origins that have many beneficial health effects (mainly antioxidant). However, they suffer from low-stability against the environmental condition. Thus, encapsulation approach emerged to decrease their sensitivity present a target delivery system. Generally, native carrier agents (polysaccharides proteins) being applied embed core materials. Accordingly, methods been developed protect vulnerable by these carriers. Spray freeze-drying common with ability of powder production. Both feed emulsion production drying process factors substantially influence embedded within agents. Spray-drying is well-known higher applicable scalable procedure food pharmaceutical industries. It predominantly related its lower costs. Nevertheless, application limited for more sensitive compounds due hot-air exertion. In contrast, has mostly used thermo-sensitive ingredients. Its restricted economic drawbacks which long time (24–48 h) required. adequately taken into an advantage therapeutic since high-added value products will be produced so biological activity needed.

Язык: Английский

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Peptides and protein hydrolysates as food preservatives and bioactive components of edible films and coatings - A review

Trends in Food Science & Technology, Год журнала: 2020, Номер 106, С. 298 - 311

Опубликована: Окт. 11, 2020

The consumer demand for food that is minimally processed and does not include artificial additives makes it necessary to look new natural sources of preservatives active packaging extends the shelf-life products. Protein hydrolysates biologically peptides isolated from proteins, due their antioxidant antimicrobial activity, can be used as preservatives. In addition, possible them in materials ingredients. this paper, possibilities using protein biopeptides are characterized ingredients extending by adding directly products, or biodegradable edible packaging. full implementation bioactive hydrolysate postponed some challenges such low chemical stability, bitter taste short-term effectiveness. Encapsulation, which also discussed work, could help overcome these limitations. It has been found added already small doses, mostly inhibit fat oxidation growth microorganisms. Edible with have shown effectiveness inhibiting pathogenic microorganisms lipid oxidation, improving safety. several studies, significant changes indicated mechanical properties surface morphology films addition peptides. Nonetheless, direction depends on type incorporated hydrolysates. a promising alternative synthetic biopolymer films. However, further research should carried out, focusing search compounds assessing

Язык: Английский

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The delivery of sensitive food bioactive ingredients: Absorption mechanisms, influencing factors, encapsulation techniques and evaluation models

Food Research International, Год журнала: 2019, Номер 120, С. 130 - 140

Опубликована: Фев. 16, 2019

Язык: Английский

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Current Evidence on the Bioavailability of Food Bioactive Peptides

Molecules, Год журнала: 2020, Номер 25(19), С. 4479 - 4479

Опубликована: Сен. 29, 2020

Food protein-derived bioactive peptides are recognized as valuable ingredients of functional foods and/or nutraceuticals to promote health and reduce the risk chronic diseases. However, although have been demonstrated exert multiple benefits by biochemical assays, cell culture, animal models, ability translate new findings into practical or commercial uses remains delayed. This fact is mainly due lack correlation in vitro with vivo functions because their low bioavailability. Once ingested, need resist action digestive enzymes during transit through gastrointestinal tract cross intestinal epithelial barrier reach target organs an intact active form health-promoting properties. Thus, for a better understanding physiological effects food peptides, extensive research studies on stability transport needed. review summarizes most current evidence those factors affecting absorptive processes recently designed models mimicking environment, well novel strategies developed currently applied enhance absorption bioavailability peptides.

Язык: Английский

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Biopolymer-liposome hybrid systems for controlled delivery of bioactive compounds: Recent advances

Biotechnology Advances, Год журнала: 2021, Номер 48, С. 107727 - 107727

Опубликована: Март 5, 2021

Язык: Английский

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Bioactive peptides derived from marine sources: Biological and functional properties

Trends in Food Science & Technology, Год журнала: 2021, Номер 119, С. 348 - 370

Опубликована: Окт. 22, 2021

Язык: Английский

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Considering food matrix and gastrointestinal effects in enhancing bioactive peptide absorption and bioavailability

Journal of Functional Foods, Год журнала: 2019, Номер 64, С. 103680 - 103680

Опубликована: Ноя. 19, 2019

Bioavailability of bioactive peptides (BAPs) represents the amount absorbed through normal pathways, after oral intake, and distributed in target tissues to exhibit properties. The small intestine is primary location gastrointestinal tract where peptide absorption mainly occurs. BAPs are beneficial health upon reaching their physiological sites action without structural changes. Despite rapid dynamic evolvement research into food peptides, there still a knowledge gap regarding bioaccessibility bioavailability for systemic circulation targeted organs. Beside digestive actions endogenous proteases peptidases, chemical nutritional compositions matrix physical forms (e.g., liquid, puree, gel, solid) also critical factors that can influence interactions, digestibility, BAPs. Detailed understanding such be explored enhancing achieving positive effects.

Язык: Английский

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A Critical Review of the Use of Surfactant-Coated Nanoparticles in Nanomedicine and Food Nanotechnology

International Journal of Nanomedicine, Год журнала: 2021, Номер Volume 16, С. 3937 - 3999

Опубликована: Июнь 1, 2021

Abstract: Surfactants, whose existence has been recognized as early 2800 BC, have had a long history with the development of human civilization. With rapid nanotechnology in latter half 20th century, breakthroughs nanomedicine and food using nanoparticles remarkable, new applications developed. The technology surfactant-coated nanoparticles, which provides functions to for use fields nanotechnology, is attracting lot attention basic research industry. This review systematically describes these “surfactant-coated nanoparticles” through various sections order: 1) surfactants, 2) application 3) nanomedicine, 4) nanotechnology. Furthermore, current progress problems recent reports discussed. Keywords: drug delivery system, targeting, science, packaging, nonionic safety assessment

Язык: Английский

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