Journal of Controlled Release,
Год журнала:
2023,
Номер
358, С. 476 - 497
Опубликована: Май 15, 2023
Antiviral
peptides
and
antiviral
polysaccharides
can
play
a
major
role
in
the
prevention
treatment
of
emerging
viral
health
problems.
These
compounds
are
biocompatible,
environmentally
friendly,
non-toxic,
cost-effective,
yet
poorly
water
soluble
vulnerable
to
enzymatic
(protease)
degradation
within
aggressive
intercellular
microenvironment.
Therefore,
they
should
be
properly
protected
delivered
viruses
host
cells
by
well-designed
nanocarriers
that
mimic
terms
size,
morphology,
smart
function.
This
literature
review
is
meant
introduce
latest
advances
(mainly
past
five
years)
nano-assemblies
comprising
or
polysaccharides.
To
best
our
knowledge,
there
no
similar
study
has
solely
sufficiently
investigated
such
nanomaterials
partially
totally
derived
from
nature.
The
rational
classification
microorganism-,
plant-,
animal-derived
polysaccharide
peptide
delivering
exploration
their
relevant
applications
will
clarify
promising
capacity
these
state-of-the-art
materials
for
number
technologies
developed
inactivate
viruses.
Signal Transduction and Targeted Therapy,
Год журнала:
2024,
Номер
9(1)
Опубликована: Фев. 21, 2024
Abstract
Inflammation-associated
diseases
encompass
a
range
of
infectious
and
non-infectious
inflammatory
diseases,
which
continuously
pose
one
the
most
serious
threats
to
human
health,
attributed
factors
such
as
emergence
new
pathogens,
increasing
drug
resistance,
changes
in
living
environments
lifestyles,
aging
population.
Despite
rapid
advancements
mechanistic
research
development
for
these
current
treatments
often
have
limited
efficacy
notable
side
effects,
necessitating
more
effective
targeted
anti-inflammatory
therapies.
In
recent
years,
nanotechnology
has
provided
crucial
technological
support
prevention,
treatment,
detection
inflammation-associated
diseases.
Various
types
nanoparticles
(NPs)
play
significant
roles,
serving
vaccine
vehicles
enhance
immunogenicity
carriers
improve
targeting
bioavailability.
NPs
can
also
directly
combat
pathogens
inflammation.
addition,
facilitated
biosensors
pathogen
imaging
techniques
This
review
categorizes
characterizes
different
NPs,
summarizes
their
applications
It
discusses
challenges
associated
with
clinical
translation
this
field
explores
latest
developments
prospects.
conclusion,
opens
up
possibilities
comprehensive
management
Biomedicine & Pharmacotherapy,
Год журнала:
2023,
Номер
170, С. 116083 - 116083
Опубликована: Дек. 31, 2023
As
we
navigate
the
modern
era,
intersection
of
time-honoured
natural
remedies
and
contemporary
scientific
approaches
forms
a
burgeoning
frontier
in
global
healthcare.
For
generations,
products
have
been
foundational
to
health
solutions,
serving
as
primary
healthcare
choice
for
80%
85%
world's
population.
These
herbal-based,
nature-derived
substances,
significant
across
diverse
geographies,
necessitate
renewed
emphasis
on
enhancing
their
quality,
efficacy,
safety.
In
current
century,
advent
biogenic
phytonanoparticles
has
emerged
an
innovative
therapeutic
conduit,
perfectly
aligning
with
principles
environmental
safety
ingenuity.
Utilizing
green
chemistry
techniques,
spectrum
metallic
nanoparticles
including
elements
such
copper,
silver,
iron,
zinc,
titanium
oxide
can
be
produced
attributes
non-toxicity,
sustainability,
economic
efficiency.
Sophisticated
herb-mediated
processes
yield
array
plant-originated
nanomaterials,
each
demonstrating
unique
physical,
chemical,
biological
characteristics.
herald
new
potentials,
encompassing
antioxidants,
anti-aging
applications,
more.
Modern
technology
further
accelerates
synthesis
within
laboratory
settings,
providing
efficient
alternative
conventional
isolation
methods.
The
collaboration
between
traditional
wisdom
advanced
methodologies
now
signals
epoch
Here,
augmentation
medicine
is
realized
through
rigorous
examination.
By
intertwining
ethical
considerations,
cutting-edge
technology,
philosophy,
realms
forge
promising
pathways
research,
development,
healing.
narrative
this
seamless
integration
marks
exciting
evolution
healthcare,
where
fusion
sustainability
innovation
crafts
future
filled
endless
possibilities
human
well-being.
research
development
crucial
unlocking
potential
revolutionizing
fields
medicine,
catalysis,
electronics,
groundbreaking
applications
enhanced
efficiency
tailored
functionalities
technologies.
This
exploration
essential
harnessing
properties
address
pressing
challenges
advance
innovations
industrial
domains.
Abstract
Infectious
diseases
present
significant
challenges
to
global
health,
thereby
extensively
affecting
both
human
society
and
the
economy.
In
recent
years,
functional
probes
have
demonstrated
remarkable
potential
as
crucial
biomedical
media
for
research
treatment
of
infectious
diseases.
Their
applications
in
realm
include
pathogen
detection,
exploration
biological
mechanisms,
development
anti‐infective
drugs.
This
review
provides
a
concise
introduction
severity,
classification,
pathogenesis
Subsequently,
we
examined
distinctiveness
design
strategies
diagnosing
treating
diseases,
shedding
light
on
their
rationale
using
typical
examples.
We
discuss
current
status
associated
with
clinical
implementation
probes.
Furthermore,
explored
prospects
these
diagnosis
aims
offer
novel
insights
into
diagnostic
broaden
disease
treatment.
Micromachines,
Год журнала:
2023,
Номер
14(10), С. 1882 - 1882
Опубликована: Сен. 30, 2023
Copper
nanoparticles
(CuNPs)
can
be
synthesized
by
green
methods
using
plant
extracts.
These
are
more
environmentally
friendly
and
offer
improved
properties
of
the
NPs
in
terms
biocompatibility
functional
capabilities.
Traditional
medicine
has
a
rich
history
utilization
herbs
for
millennia,
offering
viable
alternative
or
complementary
option
to
conventional
pharmacological
medications.
Plants
traditional
herbal
use
those
with
medicinal
candidates
used
obtain
due
their
high
complex
content
biocompounds
different
redox
capacities
that
provide
dynamic
reaction
environment
NP
synthesis.
Other
synthesis
conditions,
such
as
salt
precursor
concentration,
temperature,
time
synthesis,
pH,
have
significant
effect
on
characteristics
NPs.
This
paper
will
review
some
compounds
from
plants,
extract
obtention
alternatives,
extracts,
how
they
relate
process.
Additionally,
document
includes
diverse
applications
associated
CuNPs,
starting
antibacterial
potential
metabolic
disease
treatment,
vegetable
tissue
culture,
therapy,
cardioprotective
effect,
among
others.
Pharmaceutics,
Год журнала:
2023,
Номер
15(4), С. 1181 - 1181
Опубликована: Апрель 7, 2023
The
development
of
antiviral
treatment
and
anticancer
theragnostic
agents
in
recent
decades
has
been
associated
with
nanotechnologies,
primarily
inorganic
nanoparticles
(INPs)
metal
oxides.
large
specific
surface
area
its
high
activity
make
it
easy
to
functionalize
INPs
various
coatings
(to
increase
their
stability
reduce
toxicity),
(allowing
retention
the
affected
organ
or
tissue),
drug
molecules
(for
antitumor
therapy).
ability
magnetic
(MNPs)
iron
oxides
ferrites
enhance
proton
relaxation
tissues
serve
as
resonance
imaging
contrast
is
one
most
promising
applications
nanomedicine.
Activation
MNPs
during
hyperthermia
by
an
external
alternating
field
a
method
for
targeted
cancer
therapy.
As
therapeutic
tools,
are
carriers
delivery
pharmaceuticals
(either
antiviral)
via
targeting
(in
case
MNPs),
passive
active
(by
attaching
affinity
ligands)
targeting.
plasmonic
properties
Au
(NPs)
application
photothermal
photodynamic
therapies
have
extensively
explored
recently
tumor
treatment.
Ag
NPs
alone
combination
medicines
reveal
new
possibilities
prospects
relation
hyperthermia,
therapies,
imaging,
framework
therapy
presented
this
review.
Nanomaterials,
Год журнала:
2023,
Номер
13(22), С. 2919 - 2919
Опубликована: Ноя. 8, 2023
The
rise
of
antimicrobial
resistance
caused
by
inappropriate
use
these
agents
in
various
settings
has
become
a
global
health
threat.
Nanotechnology
offers
the
potential
for
synthesis
nanoparticles
(NPs)
with
activity,
such
as
iron
oxide
(IONPs).
IONPs
is
promising
way
to
overcome
or
pathogenicity
because
their
ability
interact
several
biological
molecules
and
inhibit
microbial
growth.
In
this
review,
we
outline
pivotal
findings
over
past
decade
concerning
methods
green
using
bacteria,
fungi,
plants,
organic
waste.
Subsequently,
delve
into
primary
challenges
encountered
utilizing
diverse
organisms
materials.
Furthermore,
compile
most
common
employed
characterization
IONPs.
To
conclude,
highlight
applications
antibacterial,
antifungal,
antiparasitic,
antiviral
agents.
Toxics,
Год журнала:
2023,
Номер
11(2), С. 135 - 135
Опубликована: Янв. 30, 2023
Autophagy
is
an
evolutionarily
conserved
cellular
system
crucial
for
homeostasis
that
protects
cells
from
a
broad
range
of
internal
and
extracellular
stresses.
decreases
metabolic
load
toxicity
by
removing
damaged
components.
Environmental
contaminants,
particularly
industrial
substances,
can
influence
autophagic
flux
enhancing
it
as
protective
response,
preventing
it,
or
converting
its
function
into
pro-cell
death
mechanism.
toxic
materials
are
also
notorious
their
tendency
to
bioaccumulate
induce
pathophysiological
vulnerability.
Many
environmental
pollutants
have
been
found
stress
which
increases
autophagy.
Increasing
autophagy
was
recently
shown
improve
resistance
reduce
genetic
damage.
Moreover,
suppressing
depleting
resources
either
toxicity,
depending
on
the
circumstances.
The
essential
process
selective
utilized
mammalian
in
order
eliminate
particulate
matter,
nanoparticles,
metals,
smoke
exposure
without
inflicting
damage
cytosolic
cigarette
aging
chief
causes
chronic
obstructive
pulmonary
disease
(COPD)-emphysema;
however,
disease’s
molecular
mechanism
poorly
known.
Therefore,
understanding
impacts
via
offers
new
approaches
risk
assessment,
protection,
preventative
actions
will
counter
harmful
effects
contaminants
human
animal
health.
Comprehensive Reviews in Food Science and Food Safety,
Год журнала:
2024,
Номер
23(3)
Опубликована: Май 1, 2024
The
environmental
challenges
posed
by
plastic
pollution
have
prompted
the
exploration
of
eco-friendly
alternatives
to
disposable
packaging
and
utensils.
Paper-based
materials,
derived
from
renewable
resources
such
as
wood
pulp,
non-wood
pulp
(bamboo
straw
reed
etc.),
recycled
paper
fibers,
are
distinguished
their
recyclability
biodegradability,
making
them
promising
substitutes
in
field
food
packaging.
Despite
merits,
like
porosity,
hydrophilicity,
limited
barrier
properties,
a
lack
functionality
restricted
potential.
To
address
these
constraints,
researchers
introduced
antimicrobial
agents,
hydrophobic
substances,
other
functional
components
improve
both
physical
properties.
This
enhancement
has
resulted
notable
improvements
preservation
outcomes
real-world
scenarios.
offers
comprehensive
review
recent
progress
paper-based
materials.
In
addition
outlining
characteristics
functions
commonly
used
substances
packaging,
it
consolidates
current
research
landscape
preparation
techniques
for
paper.
Furthermore,
explores
practical
applications
materials
agricultural
produce,
meat,
seafood,
well
ready-to-eat
Finally,
production,
application,
recycling
processes
outlined
ensure
safety
efficacy,
prospects
future
development
discussed.
Overall,
emergence
stands
out
robust
alternative
offering
compelling
solution
with
superior
capabilities.
future,
functionalities
expected
further
enhance
