Journal of The Electrochemical Society,
Год журнала:
2024,
Номер
171(9), С. 097508 - 097508
Опубликована: Сен. 2, 2024
Biosensors
are
inevitable
tools
for
biomedical
applications,
including
disease
diagnosis,
monitoring,
and
drug
management.
Integrated
with
nanotechnology,
these
biosensors
have
improved
patient
outcomes
by
providing
rapid
strategic
prognosis,
remote
access,
decreasing
the
burden
of
present-day
healthcare
facilities.
Due
to
enhanced
surface-to-volume
ratio
tunable
physicochemical
properties
nanomaterials,
nanotechnology-based
emerged
as
transformative
in
sector,
offering
unparalleled
sensitivity
specificity
detecting
analyzing
biological
molecules
targeted
diagnosis.
This
review
explores
advancements
biosensor
technology,
emphasizing
integration
various
metal
nanoparticles,
carbon
quantum
dots,
enhance
device
performance
terms
sensitivity,
selectivity,
stability.
We
discuss
operational
principles
different
types-
such
electrochemical,
optical,
solid-state,
DNA-based
sensors
their
applications
healthcare,
from
early
detection
personalized
treatment
Moreover,
delves
into
challenges,
alternate
solutions,
future
prospects
development,
highlighting
role
artificial
intelligence,
bioinformatics,
5
G
communication
creating
next-generation
smart
applications.
Critical Reviews in Analytical Chemistry,
Год журнала:
2025,
Номер
unknown, С. 1 - 29
Опубликована: Март 27, 2025
The
urgent
need
for
sensitive,
rapid,
and
reliable
diagnostic
methodologies
to
control
prevent
life-threatening
pandemic
infectious
disease,
such
as
COVID-19,
remains
a
critical
priority.
Timely
on-site
detection
of
viral
pathogens
is
essential
effective
disease
management
mitigation
societal
disruptions.
Recent
advancements
in
optical
methods
have
positioned
them
at
the
forefront
healthcare
diagnostics,
offering
high
sensitivity
specificity
viable
alternatives
conventional
techniques
Polymerase
Chain
Reaction
(PCR),
which
often
suffer
from
time
delays
limited
accessibility
resource-constrained
environments.
This
review
elucidates
potential
various
techniques,
highlighting
their
advantages
over
traditional
methods.
It
encompasses
range
modalities,
including
fluorescence-based
approaches,
Raman
spectroscopy
(RS),
Plasmonic
(e.g.,
surface
plasmon
resonance
(SPR),
localized
SPR,
(LSPR),
surface-enhanced
(SERS),
fluorescence
(SEF)),
super
resolution
microscopies
(SRMs),
attenuated
total
reflectance-Fourier
transform
infrared
(ATR-FTIR),
integrated
platforms
waveguides
molecularly
imprinted
polymer
(MIP)-based
biosensors.
Additionally,
evolution
novel
biosensors,
particularly
5th
6th
generation
challenges
related
these
technologies
were
discussed.
studies
reviewed
aims
advance
development
portable,
specific,
cost-effective
point-of-care
(POC)
devices
rapid
pathogens.
This
paper
underlines
the
critical
need
for
novel
diagnostic
techniques
against
increasing
worldwide
burden
of
neurodegenerative
disorders
(NDDs).
The
intricacies
Alzheimer's,
Parkinson's,
and
Huntington's
necessitate
very
accurate
sensitive
early
detection
strategies.
In
addition,
it
provides
an
essential
look
at
promise
role
nanotechnology
potential
nanoscale
material
technology
integration
to
revolutionize
preclinical
disease
diagnostics.
Furthermore,
allows
pinpoint
identification
biomarkers
pathological
alterations.
We
discussed
different
types
nanotools,
including
nanoparticles,
nanosensors,
imaging
agents,
nanomedicine.
process
metamorphosis,
however,
has
its
challenges.
development
these
cutting-edge
instruments
necessitates
careful
thought
on
issues
ethics,
safety,
biocompatibility.
Despite
limitations,
nanotools'
importance
in
changing
course
screening
is
undeniable.
Journal of The Electrochemical Society,
Год журнала:
2024,
Номер
171(9), С. 097508 - 097508
Опубликована: Сен. 2, 2024
Biosensors
are
inevitable
tools
for
biomedical
applications,
including
disease
diagnosis,
monitoring,
and
drug
management.
Integrated
with
nanotechnology,
these
biosensors
have
improved
patient
outcomes
by
providing
rapid
strategic
prognosis,
remote
access,
decreasing
the
burden
of
present-day
healthcare
facilities.
Due
to
enhanced
surface-to-volume
ratio
tunable
physicochemical
properties
nanomaterials,
nanotechnology-based
emerged
as
transformative
in
sector,
offering
unparalleled
sensitivity
specificity
detecting
analyzing
biological
molecules
targeted
diagnosis.
This
review
explores
advancements
biosensor
technology,
emphasizing
integration
various
metal
nanoparticles,
carbon
quantum
dots,
enhance
device
performance
terms
sensitivity,
selectivity,
stability.
We
discuss
operational
principles
different
types-
such
electrochemical,
optical,
solid-state,
DNA-based
sensors
their
applications
healthcare,
from
early
detection
personalized
treatment
Moreover,
delves
into
challenges,
alternate
solutions,
future
prospects
development,
highlighting
role
artificial
intelligence,
bioinformatics,
5
G
communication
creating
next-generation
smart
applications.
