Bioinspired polydopamine hydrogels: Strategies and applications

Progress in Polymer Science, Год журнала: 2023, Номер 146, С. 101740 - 101740

Опубликована: Сен. 17, 2023

Язык: Английский

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Developing natural polymers for skin wound healing

Bioactive Materials, Год журнала: 2023, Номер 33, С. 355 - 376

Опубликована: Ноя. 26, 2023

Natural polymers are complex organic molecules that occur in the natural environment and have not been subjected to artificial synthesis. They frequently encountered various creatures, including mammals, plants, microbes. The aforementioned commonly derived from renewable sources, possess a notable level of compatibility with living organisms, limited adverse effect on environment. As result, they hold considerable significance development sustainable environmentally friendly goods. In recent times, there has advancement investigation potential uses field biomedicine, specifically relation biomaterials exhibit antibacterial antioxidant characteristics. This review provides comprehensive overview prevalent utilized biomedical domain throughout preceding two decades. this paper, we present examination components typical methods for preparation based polymers. Furthermore, summarize application polymer materials each stage skin wound repair. Finally, key findings insights into limitations current elucidate prospects their future field.

Язык: Английский

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Multifunctional hydrogels based on chitosan, hyaluronic acid and other biological macromolecules for the treatment of inflammatory bowel disease: A review

International Journal of Biological Macromolecules, Год журнала: 2022, Номер 227, С. 505 - 523

Опубликована: Дек. 8, 2022

Язык: Английский

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Chitosan-Based Hemostatic Hydrogels: The Concept, Mechanism, Application, and Prospects

Molecules, Год журнала: 2023, Номер 28(3), С. 1473 - 1473

Опубликована: Фев. 3, 2023

The design of new hemostatic materials to mitigate uncontrolled bleeding in emergencies is challenging. Chitosan-based hydrogels have frequently been used for hemostasis due their unique biocompatibility, tunable mechanical properties, injectability, and ease handling. Moreover, chitosan (CS) absorbs red blood cells activates platelets promote hemostasis. Benefiting from these desired the application CS attracting ever-increasing research attention. This paper reviews recent progress CS-based advantageous characteristics compared traditional materials. effects mechanism, deacetylation degree, relative molecular mass, chemical modification on performance are summarized. Meanwhile, some typical applications introduced provide references preparation efficient hydrogels. Finally, future perspectives presented.

Язык: Английский

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Chitosan-based multifunctional hydrogel for sequential wound inflammation elimination, infection inhibition, and wound healing

International Journal of Biological Macromolecules, Год журнала: 2023, Номер 235, С. 123847 - 123847

Опубликована: Фев. 28, 2023

Язык: Английский

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Polysaccharide-Based Multifunctional Hydrogel Bio-Adhesives for Wound Healing: A Review

Gels, Год журнала: 2023, Номер 9(2), С. 138 - 138

Опубликована: Фев. 6, 2023

Wound healing is a long-term and complex biological process that involves multiple hemostasis, inflammation, proliferation, remodeling stages. In order to realize comprehensive systematic wound management, appropriate treatment bio-adhesives are urgently needed. Hydrogel have excellent properties show unique remarkable advantages in the field of management. This review begins with detailed description design criteria functionalities ideal hydrogel for healing. Then, recent advances polysaccharide-based multifunctional bio-adhesives, which involve chitosan, hyaluronic acid, alginate, cellulose, dextran, konjac glucomannan, chondroitin sulfate, other polysaccharides, comprehensively discussed. Finally, current challenges future research directions proposed stimulate further exploration by researchers.

Язык: Английский

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Hydrogels and Wound Healing: Current and Future Prospects

Gels, Год журнала: 2024, Номер 10(1), С. 43 - 43

Опубликована: Янв. 5, 2024

The care and rehabilitation of acute chronic wounds have a significant social economic impact on patients global health. This burden is primarily due to the adverse effects infections, prolonged recovery, associated treatment costs. Chronic can be treated with variety approaches, which include surgery, negative pressure wound therapy, dressings, hyperbaric oxygen therapy. However, each these strategies has an array limitations. existing dry dressings lack functionality in promoting healing exacerbating pain by adhering wound. Hydrogels, are commonly polymer-based swell water, been proposed as potential remedies their ability provide moist environment that facilitates healing. Their unique composition enables them absorb exudates, exhibit shape adaptability, modified incorporate active compounds such growth factors antibacterial compounds. review provides updated discussion leading natural synthetic hydrogels utilized healing, details latest advancements hydrogel technology, explores alternate approaches this field. Search engines Scopus, PubMed, Science Direct, Web were advances applications over last fifteen years.

Язык: Английский

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Rapidly degrading and mussel-inspired multifunctional carboxymethyl chitosan/montmorillonite hydrogel for wound hemostasis

International Journal of Biological Macromolecules, Год журнала: 2023, Номер 242, С. 124960 - 124960

Опубликована: Май 23, 2023

Язык: Английский

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Advances in Functional Hydrogel Wound Dressings: A Review

Polymers, Год журнала: 2023, Номер 15(9), С. 2000 - 2000

Опубликована: Апрель 23, 2023

One of the most advanced, promising, and commercially viable research issues in world hydrogel dressing is gaining functionality to achieve improved therapeutic impact or even intelligent wound repair. In addition merits ordinary dressings, functional dressings can adjust their chemical/physical properties satisfy different types, carry out corresponding reactions actively create a healing environment conducive repair, also control drug release provide long-lasting benefit. Although lot in-depth has been conducted over last few decades, very studies have properly summarized. order give researchers basic blueprint for designing motivate them develop ever-more we summarized development recent years, as well current situation future trends, light preparation mechanisms effects.

Язык: Английский

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Hydrogel-Based Skin Regeneration

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(4), С. 1982 - 1982

Опубликована: Фев. 6, 2024

The skin is subject to damage from the surrounding environment. repair of wounds can be very challenging due several factors such as severe injuries, concomitant infections, or comorbidities diabetes. Different drugs and wound dressings have been used treat wounds. Tissue engineering, a novel therapeutic approach, revolutionized treatment regeneration tissue damage. This field includes use synthetic natural biomaterials that support growth tissues organs outside body. Accordingly, demand for polymer-based strategies defects significantly increasing. Among various 3D scaffolds in hydrogel gained special significance their unique properties mimicry extracellular matrix (ECM), moisture retention, porosity, biocompatibility, biodegradability, biocompatibility properties. First, this article delineates process healing conventional methods treating It then presents an examination structure manufacturing hydrogels, followed by analysis crucial characteristics most recent advancements using purpose. Finally, it discusses potential future materials within realm healing.

Язык: Английский

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