Deciphering the Puzzle: Literature Insights on Chlamydia trachomatis-Mediated Tumorigenesis, Paving the Way for Future Research DOI Creative Commons
Rafaela Rodrigues, Carlos Sousa, Nuno Vale

и другие.

Microorganisms, Год журнала: 2024, Номер 12(6), С. 1126 - 1126

Опубликована: Май 31, 2024

Some infectious agents have the potential to cause specific modifications in cellular microenvironment that could be propitious carcinogenesis process. Currently, there are viruses and bacteria, such as human papillomavirus (HPV) Helicobacter pylori, well established risk factors for neoplasia. Chlamydia trachomatis (CT) infections one of most common bacterial sexually transmitted worldwide, recent European data confirmed a continuous rise across Europe. The infection is often asymptomatic both sexes, requiring screening program early detection. Notwithstanding, not all countries Europe it. can chronic persistent infections, resulting inflammation, plausible biological mechanisms link genital with tumorigenesis. Herein, we aimed understand epidemiological plausibility CT causing endometrial, ovarian, cervical tumors. Also, covered some best suitable vitro techniques used study this association. In addition, defend point view personalized medicine strategy treat those patients through discovery biomarkers allow This review supports need development further fundamental studies area, order investigate establish role chlamydial oncogenesis.

Язык: Английский

Impact of Dietary Probiotics on the Immune and Reproductive Physiology of Pubertal Male Japanese Quail (Coturnix coturnix japonica) Administered at the Onset of Pre-Puberty DOI
Aamir Ghafoor Khan, Naveen Kango, Rashmi Srivastava

и другие.

Probiotics and Antimicrobial Proteins, Год журнала: 2024, Номер unknown

Опубликована: Янв. 3, 2024

Язык: Английский

Процитировано

9

Pharmacological Activity of Flavonoid Quercetin and Its Therapeutic Potential in Testicular Injury DOI Open Access
Xiaohui Zhang,

Yufeng Tang,

Guangping Lu

и другие.

Nutrients, Год журнала: 2023, Номер 15(9), С. 2231 - 2231

Опубликована: Май 8, 2023

Quercetin is a natural flavonoid widely found in fruits and vegetables. Recent studies have shown that quercetin mediates multiple beneficial effects variety of organ damage diseases, considered healthcare supplement with health-promoting potential. Male infertility major health concern, testicular from causes an important etiology. Previous has protective effect on reproductive function. This may be related to the antioxidant, anti-inflammatory, anti-apoptotic biological activities quercetin. Therefore, this paper reviews mechanisms by which exerts its pharmacological activity role induced various etiologies. In addition, compiles application clinical trials, demonstrating practical regulating blood pressure inhibiting cellular senescence human patients. However, more in-depth experimental trials are needed confirm true value for prevention protection against injury.

Язык: Английский

Процитировано

21

Role of Synbiotics in Reproductive Disorders DOI
Riya Thapa, Ritu Gilhotra, Asif Ahmad Bhat

и другие.

Опубликована: Янв. 1, 2024

It has been discovered that the reproductive tract contains microbial communities, and this stable microbiome contributes to preservation of health. Probiotics have suggested as a potential technique improve health lower risk illness. proposed significant element affecting couple's health, success their pregnancy, kids is male semen microbiome. reportedly linked improved maternal child fertility, mother-child Although microbiota women fertility system most complex found among upper organs, they all work together support As result hormonal effects on female system, probiotics help maintain system's homeostasis affect children. Additionally, parental sexual probiotic treatment newborn gut colonization immune development via bacterial transmission or other indirect processes, which may negative effects. The influencing advantages synbiotic management involvement studied in vivo vitro variety beneficial outcomes, including regulation composition, control digestion, advancement cellular defense, enhancement immunity had seen. Here, we discuss recent research function wellness also synbiotics for prevention disorders are related it.

Язык: Английский

Процитировано

6

Advances in Research on the Relationship between Vaginal Microbiota and Adverse Pregnancy Outcomes and Gynecological Diseases DOI Creative Commons

Fuju Zhao,

Xianyang Hu, Chunmei Ying

и другие.

Microorganisms, Год журнала: 2023, Номер 11(4), С. 991 - 991

Опубликована: Апрель 11, 2023

The human microbiota inhabiting different parts of the body has been shown to have a significant impact on health, with gut being most extensively studied in relation disease. However, vaginal is also an essential commensal female that plays crucial role health. Despite receiving less attention than microbiota, its importance regulating reproductive immunity and complex dynamic properties increasingly recognized recent years. Advances research relationship between pregnancy outcomes & gynecological diseases women shed light maintaining healthy microbiota. In this review, we aim compile developments study microbial ecosystem health outcomes. We provide comprehensive account normal association outcomes, women. By reviewing research, hope contribute advancement academic medicine’s understanding microbiota’s raise awareness among healthcare professionals general public significance for better prevention diseases.

Язык: Английский

Процитировано

16

Characterization of the semen, gut, and urine microbiota in patients with different semen abnormalities DOI Creative Commons

Tingshuai Cao,

Shangren Wang, Yang Pan

и другие.

Frontiers in Microbiology, Год журнала: 2023, Номер 14

Опубликована: Май 24, 2023

Introduction Semen quality is decreasing worldwide, leading to increased male infertility. This study analyzed the microbiota of gut, semen, and urine in individuals with semen abnormalities identify potential probiotics pathogenic bacteria that affect parameters help develop new methods for diagnosis treatment patients abnormalities. Methods We recruited 12 normal (control group), asthenospermia but no hyperviscosity (Group_1), 6 oligospermia (Group_2), 9 severe or azoospermia (Group_3), 14 only (Group_4). The were examined by analyzing 16S ribosomal RNA gene sequence using next-generation sequencing. Results gut microbes clustered into highest number operational taxonomic units, followed semen. Furthermore, α-diversity was significantly different from microbiota. urine, all each other terms β-diversity. abundance Collinsella reduced groups 1, 3, 4. Bifidobacterium Blautia decreased Group_1, while Bacteroides Group_3. Staphylococcus 1 Finally, Lactobacillus 2 Discussion comprehensively describes differences intestinal genitourinary tract between healthy those abnormal parameters. our identified , as probiotics. bacteria. Our lays foundation a approach

Язык: Английский

Процитировано

15

Vaginal microbiome in obesity and its impact on reproduction DOI Creative Commons
Akanksha Garg, Laura Burney Ellis, Ryan Laurence Love

и другие.

Best Practice & Research Clinical Obstetrics & Gynaecology, Год журнала: 2023, Номер 90, С. 102365 - 102365

Опубликована: Июнь 13, 2023

A number of reproductive outcomes have been increasingly found to be affected by the vaginal microbiota. Obesity has become a global epidemic, affecting increasing numbers reproductive-age women, and shown risk factor for adverse female health outcomes. healthy microbiome is characterized Lactobacillus-dominance, in particular Lactobacillus crispatus; obesity associated with higher diversity lower likelihood Lactobacillus-dominance. In this review, we summarize evidence on obese women impact such as conception rates, early pregnancy, preterm birth. We further explore mechanisms which may result an altered microbial composition highlight future avenues therapeutic targeting

Язык: Английский

Процитировано

13

Probiotic Lactobacillus rhamnosus species: considerations for female reproduction and offspring health DOI
Gizem Gamze Tas, Leyla Satı

Journal of Assisted Reproduction and Genetics, Год журнала: 2024, Номер 41(10), С. 2585 - 2605

Опубликована: Авг. 22, 2024

Язык: Английский

Процитировано

4

Microbiological contamination in IVF laboratories: A narrative review DOI Creative Commons

S.D. Singh,

Nancy Nair,

Akash More

и другие.

Asian Pacific Journal of Reproduction, Год журнала: 2025, Номер unknown

Опубликована: Янв. 10, 2025

In vitro fertilization (IVF) is one of the most used assisted reproductive technology (ART) techniques today. However, success IVF procedures heavily relies on maintaining a sterile environment in laboratories. This narrative review examines effects microbiological contamination laboratories, exploring its sources, impacts outcomes, and preventive measures. We conducted complete literature search using databases such as PubMed Google Scholar, focusing studies published within last fifteen years. Our findings highlight that can significantly impair embryo quality, reduce implantation pregnancy rates, increase risk miscarriage infection. The also discusses current best practices for prevention identifies areas future research. work emphasizes critical importance stringent sterility protocols laboratories calls continued vigilance innovation optimal conditions reproduction.

Язык: Английский

Процитировано

0

The Impact of the Lactation Period Gut Microbiota of Two Different Beef Cattle Breeds on Spring-Born Calves DOI Creative Commons
Changbo Chen, Yuzhu Sha, Xiaoqiang Zhang

и другие.

Animals, Год журнала: 2025, Номер 15(2), С. 197 - 197

Опубликована: Янв. 13, 2025

To investigate the impact of maternal microbiota during lactation in different beef cattle breeds on their own immune levels, milk quality, and growth development offspring, this study measured parameters, intestinal diversity, quality Pingliang red Simmental cattle, performed a correlation analysis with offspring. Our showed that lactation, had significantly higher IL-6 levels than while latter exhibited factors such as IgG, IgA, IgM, IL-1β, TNFα. The lactating cows found were rich Bacteroidetes Fibrobacteres, proportion Actinobacteria. This difference may be related to adaptation strategies energy metabolism regulation between two breeds. In addition, revealed significant differences protein, acidity, fat, total solids. Alistipes_communis, Firmicutes_bacterium_CAG_110, Paludibacter_propionicigenes, Alistipes_sp._58_9_plus, Bacteroidales_bacterium_55_9 associated both offspring calves, including body weight, length, chest girth, cannon circumference. conclusion, provides new insights into microbiota, characteristics, effects health breeds, has important implications for breed selection management livestock industry.

Язык: Английский

Процитировано

0

Microbiome of pregnancy (literature review) DOI Creative Commons
I. V. Dankova, E. G. Deryabina,

Maria A. Malikova

и другие.

Vestnik ohrany materinstva i mladenčestva., Год журнала: 2025, Номер 1(3), С. 25 - 41

Опубликована: Янв. 14, 2025

Background. Pregnancy represents a unique immunological and physiological period during which microbial communities can have significant impact on both maternal health birth outcomes. Hormonal, immunological, metabolic changes pregnancy influence the microbiome clinical outcomes, potentially impacting well-being of mother child. Objective: generalization modern scientific concepts about relationship between composition mother’s microbiota its complications, discussion possibility predicting complications using microbiome. Materials methods. An extensive literature review was conducted MEDLINE (PubMed) database as December 2024 with following keywords filter: randomized controlled trial, meta-analysis, systematic review. Research results: Extensive research links dominance certain Lactobacillus strains to different L. cripatus being most favorable strain. Only by existing in normal symbiotic organism is it possible maintain homeostasis. Any shift balance this system leads growth opportunistic flora, turn triggers cascade disorders. GDM, PCOS, premature — these conditions features vaginal microbiocenosis. Conclusion. The female reproductive tract intestine dynamic influenced number factors. More evidence suggests that dysbiosis associated various adverse Knowledge has potential improve accuracy diagnosis, develop targeted interventions, reduce risk perinatal complications.

Язык: Английский

Процитировано

0