Current Biology, Год журнала: 2023, Номер 33(23), С. R1226 - R1228
Опубликована: Дек. 1, 2023
Язык: Английский
bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown
Опубликована: Апрель 18, 2024
Vision provides animals with detailed information about their surroundings, conveying diverse features such as color, form, and movement across the visual scene. Computing these parallel spatial requires a large network of neurons, that in distant flies humans, regions comprise half brain's volume. These brain often reveal remarkable structure-function relationships, neurons organized along maps shapes directly relate to roles processing. To unravel stunning diversity complex system, careful mapping neural architecture matched tools for targeted exploration circuitry is essential. Here, we report new connectome right optic lobe from male Drosophila central nervous system FIB-SEM volume comprehensive inventory fly's neurons. We developed computational framework quantify anatomy establishing basis interpreting how vision. By integrating this analysis connectivity information, neurotransmitter identity, expert curation, classified ~53,000 into 727 types, which are systematically described named first time. Finally, share an extensive collection split-GAL4 lines our neuron type catalog. Together, set data unlock possibilities systematic investigations vision Drosophila, foundation deeper understanding sensory
Язык: Английский
Процитировано
28
Nature, Год журнала: 2025, Номер unknown
Опубликована: Март 26, 2025
Abstract Vision provides animals with detailed information about their surroundings and conveys diverse features such as colour, form movement across the visual scene. Computing these parallel spatial requires a large network of neurons. Consequently, from flies to humans, regions in brain constitute half its volume. These often have marked structure–function relationships, neurons organized along maps shapes that directly relate roles processing. More than century anatomical studies catalogued detail cell types fly systems 1–3 , behavioural physiological experiments examined capabilities flies. To unravel diversity complex system, careful mapping neural architecture matched tools for targeted exploration this circuitry is essential. Here we present connectome right optic lobe male Drosophila melanogaster acquired using focused ion beam milling scanning electron microscopy. We established comprehensive inventory developed computational framework quantify anatomy. Together, data establish basis interpreting how vision. By integrating analysis connectivity information, neurotransmitter identity expert curation, classified approximately 53,000 into 732 types. are systematically described newly named. Finally, share an extensive collection split-GAL4 lines our neuron-type catalogue. Overall, set unlocks new possibilities systematic investigations vision foundation deeper understanding sensory
Язык: Английский
Процитировано
3
Опубликована: Янв. 3, 2025
The structure of compound eyes in arthropods has been the subject many studies, revealing important biological principles. Until recently, these studies were constrained by two-dimensional nature available ultrastructural data. By taking advantage novel three-dimensional dataset obtained using volume electron microscopy, we present first cellular-level reconstruction whole eye an insect, miniaturized parasitoid wasp Megaphragma viggianii. female M. viggianii consists 29 ommatidia and contains 478 cells. Despite almost anucleate brain, all cells contain nuclei. As larger insects, dorsal rim area that are believed to be specialized polarized light detection as reflected their corneal retinal morphology. We report presence three 'ectopic' photoreceptors. Our results offer new insights into miniaturization scaling sensory organs general.
Язык: Английский
Процитировано
1
BioEssays, Год журнала: 2024, Номер 46(5)
Опубликована: Апрель 9, 2024
Abstract The compound eyes of insects exhibit stunning variation in size, structure, and function, which has allowed these animals to use their vision adapt a huge range different environments lifestyles, evolve complex behaviors. Much our knowledge eye development been learned from Drosophila , while visual adaptations behaviors are often more striking better understood studies other insects. However, recent insects, including bees, beetles, butterflies, have begun address this gap by revealing the genetic developmental bases differences morphology key new aspects structure function. Furthermore, technical advances facilitated generation high‐resolution connectomic data insect species that enhances understanding information processing, impact changes processes on evolution behavior. Here, we review breakthroughs propose future integrated research function systems within among represents great opportunity understand remarkable diversification vision.
Язык: Английский
Процитировано
4
Опубликована: Янв. 3, 2025
The structure of compound eyes in arthropods has been the subject many studies revealing important biological principles. However, until recently, these were constrained by two-dimensional nature available ultrastructural data. Here, taking advantage novel three-dimensional dataset obtained using volume electron microscopy (vEM), we present first cellular-level reconstruction whole eye an insect, extremely miniaturized parasitoid wasp Megaphragma viggianii . female M. consists 29 ommatidia and contains 478 cells. Despite almost anucleate brain, all cells possess nuclei. Like larger insects, dorsal rim area (DRA) that putatively specialize polarized light detection as reflected their corneal retinal morphology. We report presence three ‘ectopic’ photoreceptors. Our results offer new insights into miniaturization scaling sensory organs general.
Язык: Английский
Процитировано
0
Current Biology, Год журнала: 2025, Номер 35(3), С. R110 - R124
Опубликована: Фев. 1, 2025
Unlike any other group of animals, all ant species are social: individual ants share the food they gather with their nestmates and as a consequence must repeatedly leave nest to find then return home it. These back-and-forth foraging trips have been studied for about century much our growing understanding strategies underlying animal navigation has come from these studies. One important strategy that use keep track where on trip is 'path integration', in which continuously update 'home vector' gives estimated distance direction nest. As path integration accumulates errors, it cannot be relied bring precisely home: such precision accomplished by using views acquired before start foraging. Further learning scaffolded vectors or remembered vectors, guide route help useful experienced way. Many rely olfaction well vision guidance full details paths revealed how mix innate learnt multisensory cues. Wood ants, we focus this review, take an oscillating along pheromone trail sample odours, but acquire visual information only at peaks troughs oscillations. To provide working model neural basis multimodal navigational outline anatomy functioning major central brain areas circuits - complex, mushroom bodies lateral accessory lobes involved coordination behaviour olfactory patterns. Because brains not yet well-studied, work done notably, Drosophila, silkworm moths bees derive plausible circuitry can deliver ants' strategies.
Язык: Английский
Процитировано
0
eLife, Год журнала: 2025, Номер 14
Опубликована: Фев. 5, 2025
The first complete 3D reconstruction of the compound eye a minute wasp species sheds light on nuts and bolts size reduction.
Язык: Английский
Процитировано
0
Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 439 - 456
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Опубликована: Март 28, 2025
The structure of compound eyes in arthropods has been the subject many studies, revealing important biological principles. Until recently, these studies were constrained by two-dimensional nature available ultrastructural data. By taking advantage novel three-dimensional dataset obtained using volume electron microscopy (vEM), we present first cellular-level reconstruction whole eye an insect, miniaturized parasitoid wasp Megaphragma viggianii . female M. consists 29 ommatidia and contains 478 cells. Despite almost anucleate brain, all cells contain nuclei. As larger insects, dorsal rim area (DRA) that are believed to be specialized polarized light detection as reflected their corneal retinal morphology. We report presence three ‘ectopic’ photoreceptors. Our results offer new insights into miniaturization scaling sensory organs general.
Язык: Английский
Процитировано
0
eLife, Год журнала: 2025, Номер 14
Опубликована: Май 1, 2025
The structure of compound eyes in arthropods has been the subject many studies, revealing important biological principles. Until recently, these studies were constrained by two-dimensional nature available ultrastructural data. By taking advantage novel three-dimensional dataset obtained using volume electron microscopy, we present first cellular-level reconstruction whole eye an insect, miniaturized parasitoid wasp Megaphragma viggianii . female M. consists 29 ommatidia and contains 478 cells. Despite almost anucleate brain, all cells contain nuclei. As larger insects, dorsal rim area that are believed to be specialized polarized light detection as reflected their corneal retinal morphology. We report presence three ‘ectopic’ photoreceptors. Our results offer new insights into miniaturization scaling sensory organs general.
Язык: Английский
Процитировано
0