Biodiversity and human health: A scoping review and examples of underrepresented linkages

Environmental Research, Год журнала: 2024, Номер 246, С. 118115 - 118115

Опубликована: Янв. 9, 2024

Mounting evidence supports the connections between exposure to environmental typologies––such as green spaces––and human health. However, mechanistic links that connect biodiversity (the variety of life) and health, extent supporting remain less clear. Here, we undertook a scoping review map health summarise levels associated using an established weight framework. Distinct from other reviews, provide additional context regarding environment-microbiome-health axis, evaluate buffering pathway (e.g., impacts on air pollution), examples three under- or minimally-represented linkages. The are (1) Indigenous Peoples' (2) urban social equity, (3) COVID-19. We observed moderate level support microbiota-human moderate-high broader nature pathways greenspace) various outcomes, stress reduction enhanced wellbeing improved cohesion. studies did not typically include specific metrics, indicating clear research gaps. Further is required understand causative metrics such taxonomy, diversity/richness, structure, function) outcomes. There well-established frameworks assess effects broad classifications These can assist future in linking Our underrepresented linkages highlight roles its loss lived experiences, infectious diseases, sovereignty livelihoods. More awareness these socioecological interconnections needed.

Язык: Английский

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A Placebo-controlled double-blinded test of the biodiversity hypothesis of immune-mediated diseases: Environmental microbial diversity elicits changes in cytokines and increase in T regulatory cells in young children

Ecotoxicology and Environmental Safety, Год журнала: 2022, Номер 242, С. 113900 - 113900

Опубликована: Авг. 3, 2022

Язык: Английский

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Indoor green wall affects health-associated commensal skin microbiota and enhances immune regulation: a randomized trial among urban office workers

Scientific Reports, Год журнала: 2022, Номер 12(1)

Опубликована: Апрель 20, 2022

Abstract Urbanization reduces microbiological abundance and diversity, which has been associated with immune mediated diseases. Urban greening may be used as a prophylactic method to restore diversity in cities among urbanites. This study evaluated the impact of air-circulating green walls on bacterial human skin, responses determined by blood cytokine measurements. Human subjects working offices two Finnish (Lahti Tampere) participated two-week intervention, where were installed rooms experimental group. Control group worked without walls. Skin samples collected before (Day0), during (Day14) weeks after (Day28) intervention. The relative genus Lactobacillus Shannon phylum Proteobacteria class Gammaproteobacteria increased Proteobacterial was connected lower proinflammatory IL-17A level participants Lahti. In addition, change TGF-β1 levels opposite between control As skin are considered advantageous for health, induce beneficial changes microbiome. immunomodulatory potential deserves further research attention.

Язык: Английский

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The dynamic balance of the skin microbiome across the lifespan

Biochemical Society Transactions, Год журнала: 2023, Номер 51(1), С. 71 - 86

Опубликована: Янв. 6, 2023

For decades research has centered on identifying the ideal balanced skin microbiome that prevents disease and developing therapeutics to foster this balance. However, single idealized balance may not exist. The changes across lifespan. This is reflected in dynamic shifts of microbiome's diverse, inter-connected community microorganisms with age. While there are core microbial taxa, precise composition for any individual person determined by local physiology, genetics, microbe–host interactions, microbe–microbe interactions. As a key interface environment, surface its appendages also constantly exchanging microbes close personal contacts environment. Hormone fluctuations immune system maturation drive age-dependent physiology support different structures over time. Here, we review recent insights into factors shape throughout life. Collectively, works summarized within highlight how, depending where lifespan, our supports robust communities, while still maintaining features unique us. will how disruptions can influence risk dermatological diseases as well impact lifelong health.

Язык: Английский

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Harnessing soil biodiversity to promote human health in cities

npj Urban Sustainability, Год журнала: 2023, Номер 3(1)

Опубликована: Фев. 14, 2023

Abstract Biodiversity is widely linked to human health, however, connections between health and soil biodiversity in urban environments remain poorly understood. Here, we stress that reductions elevate risks but can improve through pathways including suppressing pathogens, remediating soil, shaping a beneficial microbiome promoting immune fitness. We argue targeted enhancement of could support both outdoor indoor settings. The potential enhanced benefit reflects an important yet understudied field fundamental applied research.

Язык: Английский

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The One Health approach for allergic diseases and asthma

Allergy, Год журнала: 2023, Номер 78(7), С. 1777 - 1793

Опубликована: Апрель 29, 2023

Abstract The One Health approach is a collaborative and interdisciplinary strategy with focal point on human, animal, environmental health interconnections. can support the advanced management of allergic diseases asthma, as complex, multifactorial driven by interactions between resilience response to exposome. According concept asthma arising from exposures wide range allergens, infectious agents irritants (such pollutants) occurring indoors outdoors be heavily influenced (air, water, soil quality) intermingled animal health. These are currently impacted climate change, land use, urbanization, migration, overpopulation, many more. Thus, coordinated address underlying factors that contribute development needs focus environment, altogether. Collaborative efforts across multiple sectors, including public health, veterinary medicine, science, community engagement thus needed. A activities, monitoring surveillance data, targeted interventions reduce allergens irritants, research mechanisms drive needed move field forward. In this consensus document elaborated European Academy Allergy Clinical Immunology (EAACI) American Allergy, Asthma, (AAAAI) under practical allergy (PRACTALL) series, we provide insights into Heath aiming framework for addressing complex nature asthma.

Язык: Английский

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Social and environmental transmission spread different sets of gut microbes in wild mice

Nature Ecology & Evolution, Год журнала: 2024, Номер 8(5), С. 972 - 985

Опубликована: Май 1, 2024

Abstract Gut microbes shape many aspects of organismal biology, yet how these key bacteria transmit among hosts in natural populations remains poorly understood. Recent work mammals has emphasized either transmission through social contacts or indirect environmental contact, but the relative importance different routes not been directly assessed. Here we used a novel radio-frequency identification-based tracking system to collect long-term high-resolution data on relationships, space use and microhabitat wild population mice ( Apodemus sylvaticus ), while regularly characterizing their gut microbiota with 16S ribosomal RNA profiling. Through probabilistic modelling resulting data, identify positive statistically distinct signals transmission, captured by networks overlap home ranges, respectively. Strikingly, microorganisms biological attributes drove signals. While network effect was driven anaerobic bacteria, shared most influenced aerotolerant spore-forming bacteria. These findings support prediction that contact is important for transfer low oxygen tolerance, those can tolerate form spores may be able indirectly environment. Overall, results suggest spread biologically members mammalian microbiota.

Язык: Английский

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Scoping review on soil microbiome and gut health—Are soil microorganisms missing from the planetary health plate?

People and Nature, Год журнала: 2024, Номер 6(3), С. 1078 - 1095

Опубликована: Апрель 24, 2024

Abstract Evidence suggests that soil microorganisms, to which humans have been exposed throughout our evolutionary history, were essential for the evolution of human gut microbiome and immunological resilience. In recent decades, microbial diversity has decreased along with urbanization global loss biodiversity. At same time, prevalence chronic, non‐communicable inflammatory diseases increasing in urbanized societies. Here, we investigate whether existing literature supports hypothesis ingesting microbiota provides We focus on identifying research gaps challenges must be overcome understand effects eating A scoping review peer‐reviewed empirical was carried out. The search focused studies mammals direct contact measured host response; 12 articles, including four human, six mouse two other mammal studies, identified inclusion review. addition, seven articles related health risks associated consumption included Studies indicate soil‐bound microorganisms There is a lack intervention include study subjects test orally effect Challenges, particularly heterogeneity biological chemical properties, prevented progress fully oral intake health. results encourage development technologies allow daily exposure microbiota. Future should aimed precisely importance homeostasis Read free Plain Language Summary this article Journal blog.

Язык: Английский

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Climate change effects on the human gut microbiome: complex mechanisms and global inequities

The Lancet Planetary Health, Год журнала: 2025, Номер 9(2), С. e134 - e144

Опубликована: Фев. 1, 2025

Ongoing global climate change is affecting all aspects of life on Earth, including human health. The gut microbiota an important determinant health in humans and other organisms, but how affects remains largely unexplored. In this Review, I discuss the changing might affect by altering quantity quality food, as well environmental microbiomes, such enteric pathogen pressure host physiology. Climate change-induced variability food supply, shifts elemental macromolecular composition plant animal proliferation pathogens, direct effects high temperatures physiology alter undesirable ways, increasing burden change. importance different pathways depend many geographical, economic, ecological factors. Microbiomes populations low-income countries be disproportionally affected through greater poor mitigation diet, burden,

Язык: Английский

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Indoor microbiome and allergic diseases: From theoretical advances to prevention strategies

Eco-Environment & Health, Год журнала: 2022, Номер 1(3), С. 133 - 146

Опубликована: Сен. 1, 2022

The prevalence of allergic diseases, such as asthma, rhinitis, eczema, and sick building syndrome (SBS), has increased drastically in the past few decades. Current medications can only relieve symptoms but not cure these diseases whose development is suggested to be greatly impacted by indoor microbiome. However, no study comprehensively summarizes progress general rules field, impeding subsequent translational application. To close knowledge gaps between theoretical research practical application, we conducted a comprehensive literature review summarize epidemiological, environmental, molecular evidence microbiome studies. Epidemiological shows that potential protective microorganisms for asthma are mainly from phyla Actinobacteria Proteobacteria, risk Bacilli, Clostridia, Bacteroidia. Due extremely high microbial diversity geographic variation, different health-associated species/genera detected regions. Compared with composition, metabolites show more consistent associations health, including volatile organic compounds (MVOCs), lipopolysaccharides (LPS), indole derivatives, flavonoids. Therefore, could better indicator than taxa environmental assessments health outcome prediction. interaction characteristics (surrounding greenness, relative humidity, confinement, CO2 concentration) immunology effects (inflammatory cytokines pattern recognition receptors) briefly reviewed provide new insights disease prevention treatment. Widely used tools studies introduced facilitate standard practice precise identification health-related targets.

Язык: Английский

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