The Medical and Ecological Problems, Год журнала: 2024, Номер 28(3), С. 42 - 60
Опубликована: Дек. 30, 2024
Airborne microplastic (NP) and nanoplastic (MP) pollution has emerged as a pressing environmental concern with significant implications for human health. While MPs are present both indoors outdoors, indoor concentrations generally higher due to the abrasion of household materials, furniture, other domestic sources. NPs, when inhaled, accumulate in various lung regions, exerting toxic effects potentially leading respiratory diseases. This systematic review, conducted according PRISMA guidelines, evaluates recent experimental studies on pathogenic impact nanomicroplastics (NMPs) tissues using vivo vitro models. The review included 10 analyzing MP accumulation 90 examining pathogenetic mechanisms exposure. Research data indicates predominance polymeric fibers such polypropylene, polyethylene terephthalate, polytetrafluoroethylene, accounting nearly half structures. NMPs exhibit size- composition-dependent accumulation, smaller positively charged particles showing translocation potential systemic circulation organs. highlights synergistic heavy metals pollutants, interaction pulmonary surfactant, role exacerbating Current analysis underscores growing interest NMP-related health risks identifies knowledge gaps, including need standardization NMP toxicity testing further exploration biological systems. findings emphasize importance mitigating exposure safeguard pave way future research long-term impacts airborne
Язык: Английский