Molecularly imprinted polymers in solid-phase microextraction: Enhancing the analysis of pharmaceutical compounds across diverse sample matrices DOI Creative Commons
Rafael Oliveira Martins,

Almir Custodio Batista,

Camila Cíntia Sousa Melo Brito

и другие.

Journal of Pharmaceutical and Biomedical Analysis Open, Год журнала: 2024, Номер 4, С. 100037 - 100037

Опубликована: Авг. 8, 2024

The biomedicine scientific field has made continuous progress, introducing various pharmaceutical compounds to enhance human life. While these advancements bring benefits, the unregulated use of raises concerns, particularly regarding their presence in environment and potential adverse effects on health. Therefore, assessment by analytical strategies is imperative for comprehending appraising interactions across diverse matrices. In this sense, solid-based microextraction procedures have shed light challenging task evaluating complex samples. Moreover, miniaturized are firmly rooted principles green chemistry, thereby presenting more environmentally friendly approaches than traditional extraction methods. Consequently, significant endeavors been undertaken introduce novel sorbent materials that foster a selective interaction with target analytes. Having mind, molecularly imprinted polymers (MIPs) emerge as solution, providing binding sites capable interacting analyte within sample. integration MIPs phases led strides advancing evaluation different Hence, review offer comprehensive overview current applications combined

Язык: Английский

Application of arbuscular mycorrhizal fungi for pharmaceuticals and personal care productions removal in constructed wetlands with different substrate DOI
Bo Hu, Shanshan Hu, Jan Vymazal

и другие.

Journal of Cleaner Production, Год журнала: 2022, Номер 339, С. 130760 - 130760

Опубликована: Янв. 31, 2022

Язык: Английский

Процитировано

37

Physiological Roles of Serotonin in Bivalves: Possible Interference by Environmental Chemicals Resulting in Neuroendocrine Disruption DOI Creative Commons
Laura Canesi, Angelica Miglioli, Teresa Balbi

и другие.

Frontiers in Endocrinology, Год журнала: 2022, Номер 13

Опубликована: Фев. 25, 2022

Contaminants of Emerging Concerns (CECs) are defined as chemicals not commonly monitored in aquatic ecosystems, but with the potential to cause adverse effects on biota. CECs include Endocrine Disrupting Chemicals (EDCs) and Neuro-Endocrine disruptors (NEDs) vertebrates. However, most invertebrates only rely neuroendocrine systems maintain homeostatic processes. Although conserved components have been characterized ecologically relevant groups, limited knowledge invertebrate neuroendocrinology makes it difficult define EDCs NEDs species. The monoamine serotonin (5-hydroxytryptamine, 5-HT) acts both a neurotransmitter peripheral hormone mammals. In molluscs, 5-HT is involved multiple physiological roles molecular serotonergic system identified. This review focused bivalve molluscs. Bivalves widespread all environments, estuarine coastal areas particular, where they exposed variety chemicals. bivalves, gametogenesis spawning, oocyte maturation sperm motility, regulates heart function, gill ciliary beating, mantle/siphon ''catch'' state smooth muscle immune responses. Components transduction (receptors signaling pathways) being identified several Different shown affect system. particularly applies antidepressants, among detected human pharmaceuticals environment. selective reuptake inhibitors (SSRIs) frequently seawater tissues. Information available mechanisms action SSRIs adult bivalves summarized. Data also reported development pathways early larval stages, particular model marine mussel Mytilus galloprovincialis. Overall, data point at sensitive target for disruption bivalves. results contribute drawing Adverse Outcome Pathways (AOPs) larvae adults. basic research still needed evaluate impact key groups ecosystems.

Язык: Английский

Процитировано

30

The potential of fungi in the bioremediation of pharmaceutically active compounds: a comprehensive review DOI Creative Commons
Ayodeji Amobonye, Christiana Eleojo Aruwa, Sesan Abiodun Aransiola

и другие.

Frontiers in Microbiology, Год журнала: 2023, Номер 14

Опубликована: Июль 12, 2023

The ability of fungal species to produce a wide range enzymes and metabolites, which act synergistically, makes them valuable tools in bioremediation, especially the removal pharmaceutically active compounds (PhACs) from contaminated environments. PhACs are that have been specifically designed treat or alter animal physiological conditions they include antibiotics, analgesics, hormones, steroids. Their detrimental effects on all life forms become source public outcry due their persistent nature uncontrolled discharge into various wastewater effluents, hospital surface waters. Studies however shown fungi necessary metabolic machinery degrade complex environments, such as soil water, addition can be utilized bioreactor systems remove PhACs. In this regard, review highlights with immense potential biodegradation PhACs, enzymatic arsenal well probable mechanism biodegradation. challenges encumbering real-time application promising bioremediative approach also highlighted, areas improvement future perspective. all, paper points researchers fact bioremediation is strategy for addressing growing issue pharmaceutical contamination environment help mitigate negative impacts ecosystems human health.

Язык: Английский

Процитировано

19

In situ Production of Hydroxyl Radicals via Three‐Electron Oxygen Reduction: Opportunities for Water Treatment DOI
Zhiming Wang, Nan Hu, Lan Wang

и другие.

Angewandte Chemie, Год журнала: 2024, Номер 136(40)

Опубликована: Июль 15, 2024

Abstract The electro‐Fenton (EF) process is an advanced oxidation technology with significant potential; however, it limited by two steps: generation and activation of H 2 O . In contrast to the production via electrochemical two‐electron oxygen reduction reaction (ORR), three‐electron (3e − ) ORR can directly activate molecular yield hydroxyl radical (⋅OH), thus breaking through conceptual operational limitations traditional EF reaction. Therefore, 3e a vital for efficiently producing ⋅OH in situ, charting new path toward development green water‐treatment technologies. This review summarizes characteristics mechanisms ORR, focusing on basic principles latest progress situ efficient utilization modulation pathway, shedding light rational design catalysts, mechanistic exploration, practical applications water treatment. Finally, future developments challenges efficient, stable, large‐scale are discussed based achieving optimal regulation potential combine other

Язык: Английский

Процитировано

8

Current Challenges for Biological Treatment of Pharmaceutical-Based Contaminants with Oxidoreductase Enzymes: Immobilization Processes, Real Aqueous Matrices and Hybrid Techniques DOI Creative Commons
Helena Sá, Michele Michelin, Teresa Tavares

и другие.

Biomolecules, Год журнала: 2022, Номер 12(10), С. 1489 - 1489

Опубликована: Окт. 15, 2022

The worldwide access to pharmaceuticals and their continuous release into the environment have raised a serious global concern. Pharmaceuticals remain active even at low concentrations, therefore occurrence in waterbodies may lead successive deterioration of water quality with adverse impacts on ecosystem human health. To address this challenge, there is currently an evolving trend toward search for effective methods ensure efficient purification both drinking wastewater. Biocatalytic transformation using oxidoreductase enzymes, such as peroxidase laccase, promising environmentally friendly solution treatment, where fungal species been used preferred producers due ligninolytic enzymatic systems. Enzyme-catalyzed degradation can transform micropollutants more bioavailable or innocuous products. Enzyme immobilization carrier generally increases its stability catalytic performance, allowing reuse, being approach applicability industrial scale process. Moreover, coupling biocatalytic processes other treatment technologies revealed be achieve complete removal pharmaceuticals. This review updates state-of-the-art application oxidoreductases namely degrade from spiked real advances concerning techniques enzyme immobilization, operation bioreactors, use redox mediators, hybrid techniques, well discussion mechanisms ending toxicity, are addressed.

Язык: Английский

Процитировано

25

Determination and risk assessment of pharmaceutical residues in the urban water cycle in Selangor Darul Ehsan, Malaysia DOI Creative Commons
Zarimah Mohd Hanafiah, Wan Hanna Melini Wan Mohtar, Teh Sabariah Binti Abd Manan

и другие.

PeerJ, Год журнала: 2023, Номер 11, С. e14719 - e14719

Опубликована: Фев. 1, 2023

The environmental fate of non-steroidal anti-inflammatory drugs (NSAIDs) in the urban water cycle is still uncertain and their status mainly assessed based on specific components information human risk assessments. This study (a) explores NSAIDs (ibuprofen, IBU; naproxen, NAP; ketoprofen, KET; diazepam, DIA; diclofenac, DIC) cycle, including wastewater, river, treated via gas chromatography-mass spectrophotometry (GCMS), (b) assesses efficiency reducing targeted sewage treatment plant (STP) using analysis variance (ANOVA), (c) evaluates ecological assessment these teratogenic index (TI) quotient (RQ). primary receptor contaminants comes from areas, as a high concentration detected (ranging 5.87 × 10 3 to 7.18 4 ng/L). percentage removal STP ranged 25.6% 92.3%. NAP KET were at trace levels water, indicating persistent presence cycle. TI values for DIA (influent effluent) more than 1, showing effect. IBU, KET, DIC had less lethal embryo effects. can be classified Human Pregnancy Category C (2.1 > ≥ 0.76). work proved that exist current which could induce adverse effects humans environment (RQ low-risk categories). Therefore, they should minimized, if not eliminated, sources pollutant ( i.e ., STPs). These pollutants considered priority monitored, given focus to, listed guideline due

Язык: Английский

Процитировано

15

In situ Production of Hydroxyl Radicals via Three‐Electron Oxygen Reduction: Opportunities for Water Treatment DOI
Zhiming Wang, Nan Hu, Lan Wang

и другие.

Angewandte Chemie International Edition, Год журнала: 2024, Номер unknown

Опубликована: Авг. 23, 2024

The electro-Fenton (EF) process is an advanced oxidation technology with significant potential; however, it limited by two steps: generation and activation of H

Язык: Английский

Процитировано

6

Environmental risk assessment of pharmaceuticals in wastewaters and reclaimed water from catalan main river basins DOI

Pol Domínguez-García,

Ouwais Aljabasini,

Carlos Barata

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 949, С. 175020 - 175020

Опубликована: Июль 26, 2024

Язык: Английский

Процитировано

6

Occurrence of contaminants of emerging concern and their risks to the Pantanal Sul-Mato-Grossense aquatic biota, Brazil DOI
Lucilene Finoto Viana, Bruno do Amaral Crispim, Fábio Kummrow

и другие.

Chemosphere, Год журнала: 2023, Номер 337, С. 139429 - 139429

Опубликована: Июль 5, 2023

Язык: Английский

Процитировано

12

Improving biological removal of pharmaceutical active compounds and estrogenic activity in a mesophilic anaerobic osmotic membrane bioreactor treating municipal sewage DOI Creative Commons
Gemima Santos Arcanjo, Carolina Rodrigues dos Santos,

Bárbara F. Cavalcante

и другие.

Chemosphere, Год журнала: 2022, Номер 301, С. 134716 - 134716

Опубликована: Апрель 26, 2022

Язык: Английский

Процитировано

18