Aged Biodegradable Nanoplastics Enhance Body Accumulation Associated with Worse Neuronal Damage in Caenorhabditis elegans

Environmental Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

The environmental and health challenges posed by petroleum-based biodegradable plastics, such as polybutylene succinate (PBS) polybutyleneadipate-co-terephthalate (PBAT), are a significant concern because they increasingly present in the environment contribute substantial proportion of microplastics (MPs) or nanoplastics (NPs). In this study, ultraviolet (UV)-aged PBS-NPs PBAT-NPs found to have higher propensity accumulate within body Caenorhabditis elegans (C. elegans) prolonging defecation interval, which could induce severe neuronal damage compared pristine NPs. increased accumulation (BNPs) subsequent impairments neurobehavior highly attributed their reduced particle size altered surface properties, including changed chemical bonds functional groups after photoaging. Aged BNPs also cause more GABAergic neurons neurotransmitter receptors, resulting disrupted homeostasis behaviors. Overall, both PBS PBAT components show no differences biological mechanisms neural damage, highlighting commonalities characteristics adverse effects on nervous system. Our study opens up exploration impacts photoaging degradation state that environment.

Язык: Английский

---

Ecotoxicological impacts associated with the interplay between micro(nano)plastics and pesticides in aquatic and terrestrial environments

TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 165, С. 117133 - 117133

Опубликована: Июнь 17, 2023

Язык: Английский

---

Fosthiazate, a soil-applied nematicide, induces oxidative stress, neurotoxicity and transcriptome aberrations in earthworm (Eisenia fetida)

Journal of Hazardous Materials, Год журнала: 2023, Номер 463, С. 132865 - 132865

Опубликована: Окт. 27, 2023

Язык: Английский

---

Co-transport of degradable microplastics with Cd(Ⅱ) in saturated porous media: Synergistic effects of strong adsorption affinity and high mobility

Environmental Pollution, Год журнала: 2023, Номер 330, С. 121804 - 121804

Опубликована: Май 10, 2023

Язык: Английский

---

Are bioplastics safe? Hazardous effects of polylactic acid (PLA) nanoplastics in Drosophila

The Science of The Total Environment, Год журнала: 2024, Номер 919, С. 170592 - 170592

Опубликована: Фев. 12, 2024

The expanded uses of bioplastics require understanding the potential health risks associated with their exposure. To address this issue, Drosophila melanogaster as a versatile terrestrial in vivo model was employed, and polylactic acid nanoplastics (PLA-NPLs), proxy for bioplastics, were tested material model. Effects determined larvae exposed 4 days to different concentrations (25, 100, 400 μg/mL) 463.9 ± 129.4 nm PLA-NPLs. Transmission electron microscopy (TEM) scanning microscope (SEM) approaches permitted detection PLA-NPLs midgut lumen larvae, interacting symbiotic bacteria. Enzymatic vacuoles observed carriers, collecting enabling crossing peritrophic membrane, finally internalizing into enterocytes. Although no toxic effects egg-to-adult survival, cell uptake causes cytological disturbances formation large vacuoles. translocation across intestinal barrier demonstrated by presence hemolymph. PLA-NPL exposure triggered damage, oxidative stress, DNA inflammation responses, evaluated via wide set marker genes. Collectively, these structural molecular interferences caused generated high levels stress damage hemocytes larvae. point out need further studies aiming deepen before adopting safe plastic alternative.

Язык: Английский

---

Effects of micro-nano plastics on the environmental biogeochemical cycle of nitrogen: A comprehensive review

Chemosphere, Год журнала: 2024, Номер 357, С. 142079 - 142079

Опубликована: Апрель 18, 2024

Язык: Английский

---

Exploring the toxicity of biodegradable microplastics and imidacloprid to earthworms (Eisenia fetida) from morphological and gut microbial perspectives

Environmental Pollution, Год журнала: 2023, Номер 337, С. 122547 - 122547

Опубликована: Сен. 12, 2023

Язык: Английский

---

Unveiling the impact of short-term polyethylene microplastics exposure on metabolomics and gut microbiota in earthworms (Eudrilus euganiae)

Journal of Hazardous Materials, Год журнала: 2023, Номер 460, С. 132305 - 132305

Опубликована: Сен. 1, 2023

Язык: Английский

---

Combined effects of polyethylene microplastics and carbendazim on Eisenia fetida: A comprehensive ecotoxicological study

Environmental Pollution, Год журнала: 2024, Номер 348, С. 123854 - 123854

Опубликована: Март 23, 2024

Язык: Английский

---

Exploring the neurotoxicity of chiral dinotefuran towards nicotinic acetylcholine receptors: Enantioselective insights into species selectivity

Journal of Hazardous Materials, Год журнала: 2024, Номер 469, С. 134020 - 134020

Опубликована: Март 13, 2024

Язык: Английский

---