Efficiency of PGK1 proteins delivered to the brain via a liposomal system through intranasal route administration for the treatment of spinocerebellar ataxia type 3 DOI
Yu-Shuan Chen,

Zhen-Xiang Hong,

Yi-Tung Lin

и другие.

Drug Delivery and Translational Research, Год журнала: 2023, Номер 14(7), С. 1940 - 1953

Опубликована: Дек. 31, 2023

Язык: Английский

Ultrasound-Assisted Extraction and the Encapsulation of Bioactive Components for Food Applications DOI Creative Commons
Nitin Mehta,

S Jeyapriya.,

Pavan Kumar

и другие.

Foods, Год журнала: 2022, Номер 11(19), С. 2973 - 2973

Опубликована: Сен. 23, 2022

Various potential sources of bioactive components exist in nature which are fairly underutilized due to the lack a scientific approach that can be sustainable as well practically feasible. The recovery compounds is big challenge and its use food industry develop functional foods promising area research. techniques available for extraction these bioactives but their thermolabile nature, there demand nonthermal or green technologies lower cost operation decrease operational time energy consumption compared conventional methods. Ultrasound-assisted (UAE) gaining popularity relative advantages over solvent extraction. Thereafter, ultrasonication an encapsulating tool helps protecting core against adverse environmental conditions during processing storage. review mainly aims discuss ultrasound technology, applications, fundamental principles ultrasonic-assisted encapsulation, parameters affecting them, applications ultrasound-assisted encapsulation systems. Additionally, future research areas highlighted with emphasis on sustainability whole process.

Язык: Английский

Процитировано

71

Review of fish protein hydrolysates: production methods, antioxidant and antimicrobial activity and nanoencapsulation DOI
Mahrokh Nemati, Seyed Rasoul Shahosseini, Peiman Ariaii

и другие.

Food Science and Biotechnology, Год журнала: 2024, Номер 33(8), С. 1789 - 1803

Опубликована: Апрель 24, 2024

Язык: Английский

Процитировано

21

Ultrasonic assisted extraction of mulberry leaf protein: Kinetic model, structural and functional properties, in vitro digestion DOI
Li Zhao,

Xinya Cheng,

Xinyu Song

и другие.

Process Biochemistry, Год журнала: 2023, Номер 128, С. 12 - 21

Опубликована: Фев. 14, 2023

Язык: Английский

Процитировано

22

Ultrasonic-assisted extraction of grape seed procyanidins, preparation of liposomes, and evaluation of their antioxidant capacity DOI Creative Commons

Libin Sun,

Hong Wang, Jing Du

и другие.

Ultrasonics Sonochemistry, Год журнала: 2024, Номер 105, С. 106856 - 106856

Опубликована: Март 26, 2024

The residue remaining after oil extraction from grape seed contain abundant procyanidins. An ultrasonic-assisted enzyme method was performed to achieve a high efficiency of procyanidins when the optimal conditions were 8 U/g cellulase, ultrasound power 200 W, ultrasonic temperature 50 ℃, and reaction time 40 min. effects free on both radical scavenging activity thermal stability at 40, 60, 80 ℃ procyanidins-loaded liposomal systems prepared by discussed. presence concentrations ranging 0.02 0.10 mg/mL observed be effective inhibiting lipid oxidation 15.15 % 69.70 in linoleic acid model system during for 168 h, as measured using ferric thiocyanate method. characterized measuring mean particle size encapsulation efficiency. Moreover, holographic plots showed that effect-response points combined with α-tocopherol liposomes lower than addition line 95 confidence interval limits. At same time, there significant differences between theoretical IC

Язык: Английский

Процитировано

11

Effects of combined binding of chlorogenic acid/caffeic acid and gallic acid to trypsin on their synergistic antioxidant activity, enzyme activity and stability DOI Creative Commons
Xin Qi, He Liu,

Yongfang Ren

и другие.

Food Chemistry X, Год журнала: 2023, Номер 18, С. 100664 - 100664

Опубликована: Март 25, 2023

The combined application of multiple natural polyphenols in functional foods may provide better health benefits. binding with different structures to proteins will affect their respective functions. Spectroscopy and molecular docking were used investigate the competitive chlorogenic acid (CGA)/caffeic (CA) gallic (GA) trypsin. effects order adding three phenolic acids on assessed. stability trypsin its docked complexes CGA/CA/GA was evaluated by dynamics simulation. process activity thermal trypsin, as well antioxidant explored. CGA/CA GA affected synergistic effects. results a reference for food pharmaceutical fields.

Язык: Английский

Процитировано

20

Effect of Liposomal Encapsulation and Ultrasonication on Debittering of Protein Hydrolysate and Plastein from Salmon Frame DOI Creative Commons
Kartik Sharma, Krisana Nilsuwan, Lukai Ma

и другие.

Foods, Год журнала: 2023, Номер 12(4), С. 761 - 761

Опубликована: Фев. 9, 2023

The impacts of liposomal encapsulation on the bitterness salmon frame protein hydrolysate (SFPH) and plastein (SFPP) with aid ultrasound (20% amplitude, 750 W) for different time intervals (30, 60 120 s) were investigated. Liposomes loaded 1% (L-PH1) (L-PT1) showed highest efficiency least (p < 0.05). Ultrasonication longer times reduced (EE) increased both L-PH1 L-PT1 along a reduction in particle size. When comparing between L-PT1, latter less due to lower nature higher entrapment liposomes. In vitro release studies also delayed peptides from comparison control hydrolysate. Therefore, liposomes could be an efficient delivery system improving sensory characteristics by lowering hydrolysates.

Язык: Английский

Процитировано

14

Sustainable emerging high-intensity sonication processing to enhance the protein bioactivity and bioavailability: An updated review DOI Creative Commons
Muhammad Hussain, Munkh‐Amgalan Gantumur, Muhammad Faisal Manzoor

и другие.

Ultrasonics Sonochemistry, Год журнала: 2023, Номер 97, С. 106464 - 106464

Опубликована: Июнь 1, 2023

High-intensity ultrasound (HIU) is considered one of the promising non-chemical eco-friendly techniques used in food processing. Recently known to enhance quality, extraction bioactive compounds and formulation emulsions. Various foods are treated with ultrasound, including fats, compounds, proteins. Regarding proteins, HIU induces acoustic cavitation bubble formation, causing unfolding exposure hydrophobic regions, resulting functional, bioactive, structural enhancement. This review briefly portrays impact on bioavailability properties proteins; effect protein allergenicity anti-nutritional factors has also been discussed. can attributes plants animal-based such as antioxidant activity, antimicrobial peptide release. Moreover, numerous studies revealed that treatment could functional properties, increase release short-chain peptides, decrease allergenicity. replace chemical heat treatments bioactivity digestibility; however, its applications still research small scale, usage industries yet be implemented.

Язык: Английский

Процитировано

13

Physical Properties of Cellulose Derivative-Based Edible Films Elaborated with Liposomes Encapsulating Grape Seed Tannins DOI Creative Commons
Constanza Vidal, Johana López-Polo, Fernando Osorio

и другие.

Antioxidants, Год журнала: 2024, Номер 13(8), С. 989 - 989

Опубликована: Авг. 14, 2024

Combined use of edible films (EF) with nanoencapsulation systems could be an effective alternative for improving the films' physical properties and maintaining bioactive compounds' stability. This research work focuses on combined EF cellulose-derived biopolymers enriched liposomes that encapsulate grape seed tannins subsequent evaluation wettability. Tannin-containing liposomal suspensions (TLS) showed 570.8 ± 6.0 nm particle size 99% encapsulation efficiency. In vitro studies release from was slower than free tannins, reaching a maximum catechin 0.13 0.01%, epicatechin 0.57 gallic acid 3.90 0.001% over 144 h period. Adding to biopolymer matrices resulted in significant decrease (

Язык: Английский

Процитировано

4

Liposomes and Niosomes: New trends and applications in the delivery of bioactive agents for cancer therapy DOI
Helena de Almeida Cerqueira Kodel,

Paria Alizadeh,

Samad Nejad Ebrahimi

и другие.

International Journal of Pharmaceutics, Год журнала: 2024, Номер unknown, С. 124994 - 124994

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

4

Storage Stability and Antioxidant Properties of Vegetable and Marine Lecithin Liposomes Loaded with Sea Cucumber (Holothuria forskali) and Musky Octopus (Eledone moschata) Protein Hydrolysates DOI Creative Commons
Carolina Pascual-Silva, Ailén Alemán, P. Montero

и другие.

Food and Bioprocess Technology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 18, 2025

Abstract This study is aimed at comparing how the lipid composition of lecithins from vegetable and marine sources affects properties storage stability liposomes evaluating their capacity to encapsulate two protein hydrolysates derived undervalued invertebrates. The particle (size, polydispersity index or PDI, ζ potential), thermal properties, in vitro antioxidant angiotensin-converting enzyme (ACE) inhibitory produced soybean, sunflower, herring roe lecithin were compared. All exhibited a high polyunsaturated fatty acid (PUFA) content (52.7 − 59.18%); however, for marine-derived lecithin, rich long chain ω-3 acids, partial purification process phospholipids was required obtain stable liposomal dispersion. Mean sizes 212 nm, 130 96 nm obtained sunflower (LSun), soy (LSoy), partially purified (LMarP) liposomes, respectively, all with electronegative zeta potential. Two sea cucumber musky octopus concentrates successfully encapsulated prepared respective then characterised. provided ACE-inhibitory capacity; highly dependent on source. Unloaded loaded presented colloidal during 4 weeks chilled storage. Finally, principal component analysis (PCA) conducted summarise interpret results. Liposomes offer nutritious alternative, due long-chain omega-3 content, biological activity, favourable structural attributes.

Язык: Английский

Процитировано

0