British Journal Of Nutrition,
Год журнала:
2024,
Номер
unknown, С. 1 - 10
Опубликована: Ноя. 11, 2024
The
influence
of
the
SNP
rs174575
(C/G)
within
fatty
acid
desaturase
2
gene
on
levels
long-chain
PUFA
was
determined
through
statistical
meta-analysis.
Six
databases
were
searched
to
retrieve
relevant
literature.
Original
data
analysed
using
Stata
17·0,
encompassing
summary
statistics,
tests
for
heterogeneity,
assessment
publication
bias,
subgroup
analysis
and
sensitivity
analysis.
A
total
ten
studies
identified
grouped
into
twelve
trials.
Our
results
showed
that
individuals
who
carried
minor
G
allele
had
significantly
higher
dihomo-
Prostaglandins Leukotrienes and Essential Fatty Acids,
Год журнала:
2024,
Номер
202, С. 102627 - 102627
Опубликована: Март 1, 2024
The
growing
interest
in
Omega-3
fatty
acids
as
diagnostic
markers
or
new
therapeutic
approaches
also
for
COVID-19
disease,
led
us
to
investigate
the
presence
of
potential
correlations
between
acids'
levels
whole
blood
and
days
hospitalization
admission
paediatric
intensive
care
unit
(PICU)
51
children
with
MIS-C
diagnosis
following
SARS-CoV-2
infection.
A
statistically
significant
negative
correlation
was
observed
docosapentaenoic
acid
(22:5n-3,DPA),
docosahexaenoic
(DHA)
total
FA
levels.
Dividing
study
group
into
quartiles
according
Omega-3-Index
(O3I),
no
difference
respect
PICU
rate.
In
contrast,
number
Q4
(O3I
≥
2.51
%)
different
from
groups
Q1-3
<
%),
subjects
showing
higher
O3I
needing
shorter
hospitalizations
than
lower
O3I.
According
previous
investigating
adults
affected
by
Sars-cov-2
we
explored
this
nutrients
MIS-C.
Our
exploratory
shows
that
high
DPA,
DHA
could
be
effective
reducing
length
hospitalization.
Ageing Research Reviews,
Год журнала:
2024,
Номер
100, С. 102432 - 102432
Опубликована: Июль 17, 2024
It
is
imperative
to
optimise
health
and
healthspan
across
the
lifespan.
The
accumulation
of
reactive
oxygen
species
(ROS)
has
been
implicated
in
hallmarks
ageing
inhibiting
ROS
production
can
potentially
delay
whilst
increasing
healthy
longevity.
Lipids
lipid
mediators
(derivatives
lipids)
are
becoming
increasingly
recognized
as
central
molecule
tissue
cellular
function
susceptible
peroxidation;
hence
linked
with
ageing.
Lipid
classes
process
include
sterols,
glycerophospholipids,
sphingolipids
oxidation
products
polyunsaturated
fatty
acids
but
these
not
yet
translated
into
clinic.
Further
mechanistic
studies
required
for
understanding
process.
Lipidomics,
system
level
characterisation
respect
metabolism
function,
might
provide
a
significant
useful
biological
age
profiling
tool
through
longitudinal
studies.
profiles
different
ages
among
individuals
could
be
harnessed
biomarkers
potential
integration
development
lipid-based
clock
(lipid
clock).
includes
prediction
future
morbidity
or
mortality,
which
will
promote
precision
longevity
medicine.
Current Opinion in Clinical Nutrition & Metabolic Care,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 3, 2024
Purpose
of
review
Several
types
injectable
lipid
emulsions
(ILEs)
have
become
available
for
parenteral
nutrition.
The
purpose
this
is
to
highlight
the
most
recent
and
interesting
articles
in
field
ILEs.
Recent
findings
literature
has
compared
ILEs
various
clinical
scenarios
(e.g.
abdominal
surgery,
chronic
intestinal
failure,
critical
illness,
preterm
birth).
Favorable
effects
containing
fish
oil
been
observed
studies
on
surgical
patients
with
Crohn's
disease,
critically
ill
patients,
failure-associated
liver
dysfunction,
whereas
other
trials
shown
no
clear
benefit.
Ongoing
research
focused
finding
novel
strategies
reduce
toxicity
ILEs,
including
use
‘artificial
intelligence’
tools
organoids.
Promising
new
applications
are
emerging,
prevention
neonatal
hypoxic
brain
injury.
Summary
Although
goal
reducing
levels
pro-inflammatory
omega-6
fatty
acids
appear
confer
some
advantage
settings
surgery),
conclusive
data
superiority
one
ILE
over
another
lacking.
In
particular,
needed
compare
different
mixed-oil
each
pure
Frontiers in Psychology,
Год журнала:
2024,
Номер
15
Опубликована: Май 2, 2024
Background
With
increased
life
expectancy,
cognitive
decline
has
emerged
as
a
prevalent
neurodegenerative
disorder.
Objective
This
study
aimed
to
examine
the
correlation
between
concentrations
of
Plasma
long-chain
n-3
polyunsaturated
fatty
acids
(LCPUFAs)
and
performance
in
elderly
Americans.
Methods
Data
were
analyzed
from
older
adults
enrolled
two
NHANES
cycles.
Participants
completed
four
assessments,
including
Immediate
Recall
Test
(IRT),
Delayed
(DRT),
Animal
Fluency
(AFT),
Digit
Symbol
Substitution
(DSST).
Linear
regression
restricted
cubic
spline
modeling
examined
associations
plasma
LCPUFAs
levels
test
outcomes.
Results
The
cohort
included
610
aged
69
years
on
average,
300
(49.2%)
males
310
(50.8%)
females.
median
concentration
was
309.4
μmol/L,
with
an
interquartile
range
244.7–418.9
μmol/L.
In
unadjusted
adjusted
generalized
linear
model
analyses,
circulating
exhibited
significant
positive
correlations
DRT
performance.
No
relationships
detected
among
those
chronic
conditions
(chronic
heart
failure,
stroke,
diabetes).
A
association
scores
evident
but
not
Conclusion
significantly
associated
free
illnesses,
diabetes.
British Journal Of Nutrition,
Год журнала:
2024,
Номер
unknown, С. 1 - 10
Опубликована: Ноя. 11, 2024
The
influence
of
the
SNP
rs174575
(C/G)
within
fatty
acid
desaturase
2
gene
on
levels
long-chain
PUFA
was
determined
through
statistical
meta-analysis.
Six
databases
were
searched
to
retrieve
relevant
literature.
Original
data
analysed
using
Stata
17·0,
encompassing
summary
statistics,
tests
for
heterogeneity,
assessment
publication
bias,
subgroup
analysis
and
sensitivity
analysis.
A
total
ten
studies
identified
grouped
into
twelve
trials.
Our
results
showed
that
individuals
who
carried
minor
G
allele
had
significantly
higher
dihomo-
