Green Chemistry, Год журнала: 2022, Номер 24(3), С. 1342 - 1349
Опубликована: Янв. 1, 2022
Electrocatalysis for the controllable coupling of thiols with DCE was achieved to generate value-added β-chloro-tethered sulfur compounds in batch and flow.
Язык: Английский
European Journal of Medicinal Chemistry, Год журнала: 2022, Номер 236, С. 114317 - 114317
Опубликована: Апрель 1, 2022
Язык: Английский
Процитировано
40
Journal of Cleaner Production, Год журнала: 2023, Номер 398, С. 136616 - 136616
Опубликована: Фев. 25, 2023
Язык: Английский
Процитировано
39
ACS Catalysis, Год журнала: 2023, Номер 13(12), С. 7756 - 7794
Опубликована: Май 25, 2023
A selection of perfluoroalkylation reactions aliphatic substrates that display methodological and synthetic amplitude will be studied, giving examples their applications mechanistic details. An array approaches for fluoroalkylation are documented; in particular, radical protocols prominent among methods. To effect, addition perfluoroalkyl radicals RF (RF=CnF2n+1, n > 1) to unsaturated organic serve as one the most direct efficacious ways access fluoroalkylated scaffolds. The syntheses perfluoroalkyl-substituted vinyl, alkynyl, allylic compounds; hydro-, iodo-, oxy-perfluoroalkylated alkanes olefins; carbonyl enamides, amides, thioamides, hydrazones; multicomponent studied. While there a number accomplished reports on organofluorination, we aim provide an overview radical-involved substrates, covering from 2018 early 2023, summarized Tables 1–4.
Язык: Английский
Процитировано
39
Chemistry - An Asian Journal, Год журнала: 2023, Номер 18(9)
Опубликована: Март 15, 2023
Electrochemical dearomative spirocyclization serves as a green and sustainable approach to convert the flat, two-dimension aromatic feedstock into value-added three-dimension spirocyclic architectures. This review highlights recent advances, emphasizes mechanistic discussions, showcases synthetic applications of this emerging versatile powerful transformation.
Язык: Английский
Процитировано
36
World Journal of Microbiology and Biotechnology, Год журнала: 2023, Номер 39(11)
Опубликована: Сен. 2, 2023
Abstract Fungi have been extensively studied for their capacity to biotransform a wide range of natural and xenobiotic compounds. This versatility is reflection the broad substrate specificity fungal enzymes such as laccases, peroxidases cytochromes P450, which are involved in these reactions. review gives an account recent advances understanding metabolism drugs pollutants dyes, agrochemicals per- poly-fluorinated alkyl substances (PFAS), describes key biotransformation. The potential fungi bioremediation polluted environments biocatalytic production important compounds also discussed.
Язык: Английский
Процитировано
29
ChemCatChem, Год журнала: 2021, Номер 13(7), С. 1722 - 1729
Опубликована: Янв. 21, 2021
Abstract Methanol is a potential hydrogen source and C 1 synthon, which finds interesting applications in both chemical synthesis energy technologies. The effective utilization of this simple alcohol organic central importance attracts scientific interest. Herein, we report clean cost‐competitive method with the use methanol as synthon H 2 for selective N ‐methylation amines by employing relatively cheap RuCl 3 .xH O ligand‐free catalyst. This readily available catalyst tolerates various comprising electron‐deficient electron‐donating groups allows them to transform into corresponding ‐methylated products moderate excellent yields. In addition, few marketed pharmaceutical agents (e. g., venlafaxine imipramine) were also successfully synthesized via late‐stage functionalization from feedstock chemicals, highlighting synthetic value advanced reaction. Using platform, attempted tandem reactions selected nitroarenes convert using MeOH under ‐free conditions including transfer hydrogenation nitroarenes‐to‐anilines prepared drug molecules benzocaine butamben) well key intermediates. We further enable one‐shot green syntheses 1‐methylbenzimidazole ortho ‐phenylenediamine (OPDA) coupling partners.
Язык: Английский
Процитировано
52
Green Synthesis and Catalysis, Год журнала: 2021, Номер 2(3), С. 303 - 306
Опубликована: Апрель 20, 2021
A simple and efficient cross-coupling of aryl halides with different alkyl disulfides under mild conditions was developed. This C–S bond formation method carried out in the absence transition-metal external photosensitizer air. Excellent yields were obtained a broad substrate scope conditions, tolerating various functional groups.
Язык: Английский
Процитировано
48
The Journal of Organic Chemistry, Год журнала: 2021, Номер 86(22), С. 16162 - 16170
Опубликована: Авг. 6, 2021
Electrocarboxylation of organic halides is one the most investigated electrochemical approaches for converting thermodynamically inert carbon dioxide (CO2) into value-added carboxylic acids. By their sulfone derivatives, we have developed a highly efficient desulfonylative carboxylation protocol. Such strategy takes advantage CO2 as abundant C1 building block facile preparation multifunctionalized acids, including nonsteroidal anti-inflammatory drug ibuprofen, under mild reaction conditions.
Язык: Английский
Процитировано
47
Green Synthesis and Catalysis, Год журнала: 2021, Номер 2(3), С. 267 - 274
Опубликована: Июнь 18, 2021
Light may participate in biocatalytic processes either by direct light-induced biocatalysis or cascading chemical reactions with ones, which are acknowledged as photocatalysis. As it combines the strength of chemocatalysis and biocatalysis, photobiocatalysis provides attractive advantages towards green synthesis terms atom efficiency, selectivity promiscuity. Particularly, has demonstrated its unique power C–H bond functionalization. Versatile approaches, mostly via combining photocatalytic one pot, have been developed to synthesize a broad range valuable compounds. The include hydroxylation, halogenation, amination ring-expansion bonds. In this mini-review, we critically summarize recent advances functionalization photocatalysts enzymes cascade reactions, hope that potentials offered will trigger further enthusiasm research field reactions.
Язык: Английский
Процитировано
45
Frontiers in Bioengineering and Biotechnology, Год журнала: 2021, Номер 9
Опубликована: Июнь 16, 2021
Catalysis is a process carried out in the presence of heterogenous catalyst for accelerating rate chemical reaction. It plays pivotal role transition from take, make, and dispose technology to sustainable via chemo- biocatalytic processes. However, chemocatalyzed reactions are usually associated with copious amounts perilous/hazardous environmental footprints. Therefore, whole-cell biotransformations or enzyme cocktails serve as cleaner alternatives replacing classical procedures. These benchmark bioconversion important key achieving goals green chemistry by eliminating waste generation at source. For this, nature has always been driving force fuelling natural product discovery related applications. The fungal endophytic community, particular, undergone co-evolution their host plant emerged powerful tool genetic diversity. They can treasure trove biocatalysts, catalyzing organic transformations wide range substances into enantiopure compounds biotechnological relevance. Additionally, potential fungi whole-intact organisms/isolated systems greatly expanded beyond existing boundaries advancement high-throughput screening, molecular biology techniques, metabolic engineering, protein engineering. present review illustrates promising applications biocatalysts synthesis new structural analogs pharmaceutical intermediates refinement proteins novel chemistries.
Язык: Английский
Процитировано
42