Polymers,
Год журнала:
2024,
Номер
16(11), С. 1492 - 1492
Опубликована: Май 24, 2024
Inulin,
a
natural
polysaccharide,
has
emerged
as
promising
precursor
for
the
preparation
of
hydrogels
due
to
its
biocompatibility,
biodegradability,
and
structural
versatility.
This
review
provides
comprehensive
overview
recent
progress
in
preparation,
characterization,
diverse
applications
inulin-based
hydrogels.
Different
synthesis
strategies,
including
physical
methods
(thermal
induction
non-thermal
induction),
chemical
(free-radical
polymerization
crosslinking),
enzymatic
approaches,
are
discussed
detail.
The
unique
properties
hydrogels,
such
stimuli-responsiveness,
antibacterial
activity,
their
potential
fat
replacers,
highlighted.
Special
emphasis
is
given
drug
delivery
systems,
especially
colon-targeted
delivery,
selective
degradation
inulin
via
colonic
microflora.
ability
incorporate
both
hydrophilic
hydrophobic
drugs
further
expands
therapeutic
potential.
In
addition,
responsive
materials,
food
industry,
wound
dressings,
tissue
engineering
discussed.
While
significant
been
achieved,
challenges
prospects
optimizing
synthesis,
improving
mechanical
properties,
exploring
new
functionalities
Overall,
this
highlights
remarkable
class
biomaterials
with
immense
biomedical,
pharmaceutical,
materials
science
fields.
International Journal of Molecular Sciences,
Год журнала:
2022,
Номер
23(18), С. 10975 - 10975
Опубликована: Сен. 19, 2022
Chitosan,
a
naturally
abundant
cationic
polymer,
is
chemically
composed
of
cellulose-based
biopolymers
derived
by
deacetylating
chitin.
It
offers
several
attractive
characteristics
such
as
renewability,
hydrophilicity,
biodegradability,
biocompatibility,
non-toxicity,
and
broad
spectrum
antimicrobial
activity
towards
gram-positive
gram-negative
bacteria
well
fungi,
etc.,
because
which
it
receiving
immense
attention
biopolymer
for
plethora
applications
including
drug
delivery,
protective
coating
materials,
food
packaging
films,
wastewater
treatment,
so
on.
Additionally,
its
structure
carries
reactive
functional
groups
that
enable
reactions
electrochemical
interactions
at
the
biomolecular
level
improves
chitosan's
physicochemical
properties
functionality.
This
review
article
highlights
extensive
research
about
properties,
extraction
techniques,
recent
developments
chitosan-based
composites
drug,
gene,
protein,
vaccine
delivery
applications.
Its
versatile
in
tissue
engineering
wound
healing
are
also
discussed.
Finally,
challenges
future
perspectives
chitosan
biomedical
elucidated.
Recently,
hydrogels
have
been
investigated
for
the
controlled
release
of
bioactive
molecules,
such
as
living
cell
encapsulation
and
matrices.
Due
to
their
remote
controllability
quick
response,
are
widely
used
various
applications,
including
drug
delivery.
The
rate
extent
which
drugs
reach
targets
highly
dependent
on
carriers
in
delivery
systems;
therefore
demand
biodegradable
intelligent
is
progressively
increasing.
nature
hydrogel
has
created
much
interest
its
use
systems.
first
part
this
review
focuses
emerging
fabrication
strategies
hydrogel,
physical
chemical
cross-linking,
well
radiation
cross-linking.
second
describes
applications
fields,
In
end,
an
overview
application
prepared
from
several
natural
polymers
presented.
