Advanced Healthcare Materials,
Год журнала:
2024,
Номер
13(13)
Опубликована: Фев. 10, 2024
Cultured
Meat
(CM)
is
a
growing
field
in
cellular
agriculture,
driven
by
the
environmental
impact
of
conventional
meat
production,
which
contributes
to
climate
change
and
occupies
≈70%
arable
land.
As
demand
for
alternatives
rises,
research
this
area
expands.
CM
production
relies
on
tissue
engineering
techniques,
where
limited
number
animal
cells
are
cultured
vitro
processed
create
meat-like
comprising
muscle
adipose
components.
Currently,
primarily
produced
small
scale
pilot
facilities.
Producing
large
cell
mass
based
suitable
sources
bioreactors
remains
challenging.
Advanced
manufacturing
methods
innovative
materials
required
subsequently
process
into
products
scale.
Consequently,
closely
linked
with
biofabrication,
suite
technologies
precisely
arranging
aggregates
cell-material
composites
construct
specific
structures,
often
using
robotics.
This
review
provides
insights
contemporary
biomedical
biofabrication
technologies,
focusing
significant
advancements
production.
Novel
biofabricating
also
discussed,
emphasizing
their
edibility
incorporation
healthful
Finally,
initial
studies
biofabricated
examined,
addressing
current
limitations
future
challenges
large-scale
Pharmaceutics,
Год журнала:
2023,
Номер
15(3), С. 807 - 807
Опубликована: Март 1, 2023
Chitosan
is
a
chitin-derived
biopolymer
that
has
shown
great
potential
for
tissue
regeneration
and
controlled
drug
delivery.
It
numerous
qualities
make
it
attractive
biomedical
applications
such
as
biocompatibility,
low
toxicity,
broad-spectrum
antimicrobial
activity,
many
others.
Importantly,
chitosan
can
be
fabricated
into
variety
of
structures
including
nanoparticles,
scaffolds,
hydrogels,
membranes,
which
tailored
to
deliver
desirable
outcome.
Composite
chitosan-based
biomaterials
have
been
demonstrated
stimulate
in
vivo
the
repair
various
tissues
organs,
but
not
limited
to,
bone,
cartilage,
dental,
skin,
nerve,
cardiac,
other
tissues.
Specifically,
de
novo
formation,
resident
stem
cell
differentiation,
extracellular
matrix
reconstruction
were
observed
multiple
preclinical
models
different
injuries
upon
treatment
with
formulations.
Moreover,
proven
efficient
carriers
medications,
genes,
bioactive
compounds
since
they
maintain
sustained
release
these
therapeutics.
In
this
review,
we
discuss
most
recently
published
organ
well
delivery
Frontiers in Bioengineering and Biotechnology,
Год журнала:
2023,
Номер
10
Опубликована: Янв. 11, 2023
Polymer
grafting
is
a
technique
to
improve
the
morphology,
chemical,
and
physical
properties
of
polymer.
This
has
potential
existing
conduction
polymers
other
than
charge
transport;
as
result,
it
enhances
solubility,
nano-dimensional
biocompatibility,
bio-communication,
property
parent
A
polymer’s
physicochemical
can
be
modified
even
further
by
creating
copolymer
with
another
polymer
or
grafting.
Here
in
various
chemical
approaches
for
grafting,
like
free
radical,
click
reaction,
amide
formation,
alkylation
have
been
discussed
their
importance,
moreover
process
its
importance
are
covered
comprehensively
scientific
explanation.
The
present
review
also
covers
effectiveness
graft-to
application
fields,
which
will
give
reader
glimpse
about
uses.
Advanced Materials,
Год журнала:
2024,
Номер
36(34)
Опубликована: Июнь 11, 2024
The
repair
and
functional
reconstruction
of
bone
defects
resulting
from
severe
trauma,
surgical
resection,
degenerative
disease,
congenital
malformation
pose
significant
clinical
challenges.
Bone
tissue
engineering
(BTE)
holds
immense
potential
in
treating
these
defects,
without
incurring
prevalent
complications
associated
with
conventional
autologous
or
allogeneic
grafts.
3D
printing
technology
enables
control
over
architectural
structures
at
multiple
length
scales
has
been
extensively
employed
to
process
biomimetic
scaffolds
for
BTE.
In
contrast
inert
grafts,
next-generation
smart
possess
a
remarkable
ability
mimic
the
dynamic
nature
native
extracellular
matrix
(ECM),
thereby
facilitating
regeneration.
Additionally,
they
can
generate
tailored
controllable
therapeutic
effects,
such
as
antibacterial
antitumor
properties,
response
exogenous
and/or
endogenous
stimuli.
This
review
provides
comprehensive
assessment
progress
3D-printed
BTE
applications.
It
begins
an
introduction
physiology,
followed
by
overview
technologies
utilized
scaffolds.
Notable
advances
various
stimuli-responsive
strategies,
efficacy,
applications
are
discussed.
Finally,
highlights
existing
challenges
development
implementation
scaffolds,
well
emerging
this
field.
Separations,
Год журнала:
2023,
Номер
10(11), С. 565 - 565
Опубликована: Ноя. 10, 2023
The
long-term
sustainability
of
the
global
water
supply,
with
a
paramount
emphasis
on
cleanliness
and
safety,
stands
as
formidable
challenge
in
our
modern
era.
In
response
to
this
pressing
issue,
adsorption
techniques
have
emerged
pivotal
widely
recognized
solutions
for
removal
hazardous
pollutants,
particular
lead
from
wastewater.
This
comprehensive
review
explores
relentless
advancements
made
domain,
highlighting
innovations
using
separation
purification
that
surpass
traditional
metal
oxide-based
adsorbents.
Of
note
is
growing
exploration
alternative
materials,
such
starch,
chitosan,
nanoscale
structures
like
zeolites
metal-organic
frameworks,
magnetic
carbon-based
substances
development
inorganic
These
their
remarkable
capacity
structural
adjustment,
possess
extraordinary
capabilities
effective
contaminant
removal,
facilitating
swift
purification.
literature
survey
was
conducted
Google
Scholar
engine,
“adsorbents
remediation”
starting
keywords,
resulting
approximately
6000
papers.
search
refined
focus
last
three
years
specifically
targeted
papers
which
are
most
relevant
remediation.
More
than
100
were
analysed
investigate
various
techniques,
surface
modifications,
adsorbent
materials
managing
pollutants
water.
also
illuminates
research
limitations,
specific
starch-based
adsorbents
As
we
progress
towards
practical
commercial
applications,
identifies
challenges
associated
provides
invaluable
insights
into
future
prospects.
Surface
modification
emerges
promising
path,
potential
substantially
enhance
capacity,
potentially
doubling
or
even
quadrupling
it.
Moreover,
demonstrate
impressive
regenerative
capabilities,
maintaining
up
90%
regeneration
efficiency
after
multiple
cycles.
conclusion,
show
considerable
agents
aquatic
environments.
Nevertheless,
need
further
persists,
emphasizing
optimization
process
exploring
stability
real-world
scenarios.
Wound
healing
is
an
evolving
and
intricate
technique
that
vital
to
the
restoration
of
tissue
integrity
function.
Over
past
few
decades,
chitosan
a
biopolymer
derived
from
chitin,
became
known
as
emerging
biomaterial
in
field
wounds
due
its
distinctive
characteristics
including
biocompatibility,
biodegradability,
affinity
biomolecules,
wound-healing
activity.
This
natural
polymer
exhibits
excellent
capabilities
by
accelerating
development
new
skin
cells,
reducing
inflammation,
preventing
infections.
Due
distinct
biochemical
innate
antibacterial
activity,
has
been
extensively
researched
wound
dressing.
Chronic
wounds,
such
diabetic
ulcers
liver
disease,
are
growing
medical
problem.
Chitosan-based
biomaterials
promising
solution
domain
care.
The
article
analyzes
depth
chitosan-based
their
impact
on
also
methods
enhance
advantages
incorporating
bioactive
compounds.
literature
review
aimed
improve
understanding
knowledge
about
use
healing.
