Supramolecular Materials,
Год журнала:
2024,
Номер
3, С. 100064 - 100064
Опубликована: Янв. 18, 2024
Bacterial
infections
arising
from
antibiotic-resistant
strains
represent
a
formidable
global
health
threat.
In
the
realm
of
antibacterial
therapies,
supramolecular
hydrogels
stand
out
with
unique
advantages
owing
to
their
adaptable
and
flexible
non-covalent
interactions
diverse
biomolecules.
Their
ability
encapsulate
variety
biologically
active
agents
through
co-assembly
further
amplifies
efficacy,
endowing
these
hybrid
spectrum
functionalities
within
unified
system.
Various
encompass
self-healing,
injectability,
tissue
adhesion,
facile
drug
loading,
controlled
release
mechanisms,
biocompatibility,
properties,
antioxidative
attributes.
This
review
article
delves
into
two
categories
hydrogels:
i)
those
intrinsic
attributes
ii)
co-assembled
formed
integration
an
assortment
agents,
including
various
nanomaterials,
antibiotics,
compounds
derived
natural
sources,
polymers.
The
anticipated
role
hydrogels,
coupled
contemporary
medical
technologies
devices,
is
paramount
in
development
highly
effective
secure
platforms
for
therapy.
Furthermore,
addresses
current
challenges
while
elucidating
prospective
future
advancements
this
field.
Journal of Nanobiotechnology,
Год журнала:
2023,
Номер
21(1)
Опубликована: Июнь 13, 2023
Developing
an
antibiotic-free
wound
dressing
with
effective
hemostasis
and
antibacterial
antioxidant
capacity
is
highly
desirable.
In
this
work,
a
three-dimensional
(3D)
chitosan/polyvinyl
alcohol-tannic
acid
porous
nanofiber
sponge
(3D-TA)
was
prepared
via
electrospinning.
Compared
two-dimensional
(2D)
fiber
membrane,
the
unique
fluffy
3D-TA
had
high
porosity,
water
absorption
retention
ability,
hemostatic
capacity.
Furthermore,
3D
functionalized
by
tannic
(TA)
endow
without
loading
antibiotics.
addition,
composite
sponges
have
shown
biocompatibility
against
L929
cells.
The
in
vivo
experiment
shows
enable
to
accelerate
healing.
This
newly
hold
great
potential
as
dressings
for
future
clinical
application.
Frontiers in Bioengineering and Biotechnology,
Год журнала:
2023,
Номер
11
Опубликована: Июль 27, 2023
Skin
indicates
a
person’s
state
of
health
and
is
so
important
that
it
influences
emotional
psychological
behavior.
In
this
context,
the
effective
treatment
wounds
major
concern,
since
several
conventional
wound
healing
materials
have
not
been
able
to
provide
adequate
healing,
often
leading
scar
formation.
Hence,
development
innovative
biomaterials
for
essential.
Natural
synthetic
polymers
are
used
extensively
dressings
scaffold
production.
Both
natural
beneficial
properties
limitations,
they
in
combination
overcome
their
individual
limitations.
The
use
different
production
has
proven
be
promising
alternative
wounds,
as
capacity
accelerate
process
demonstrated
many
studies.
Thus,
work
focuses
on
describing
currently
commercially
available
solutions
management
skin
such
polymeric
substitutes.
New
directions,
strategies,
technologies
design
also
addressed,
providing
deep
burns,
personalized
care
faster
healing.
Polymers,
Год журнала:
2023,
Номер
15(9), С. 2000 - 2000
Опубликована: Апрель 23, 2023
One
of
the
most
advanced,
promising,
and
commercially
viable
research
issues
in
world
hydrogel
dressing
is
gaining
functionality
to
achieve
improved
therapeutic
impact
or
even
intelligent
wound
repair.
In
addition
merits
ordinary
dressings,
functional
dressings
can
adjust
their
chemical/physical
properties
satisfy
different
types,
carry
out
corresponding
reactions
actively
create
a
healing
environment
conducive
repair,
also
control
drug
release
provide
long-lasting
benefit.
Although
lot
in-depth
has
been
conducted
over
last
few
decades,
very
studies
have
properly
summarized.
order
give
researchers
basic
blueprint
for
designing
motivate
them
develop
ever-more
we
summarized
development
recent
years,
as
well
current
situation
future
trends,
light
preparation
mechanisms
effects.
