Journal of Pharmacy And Bioallied Sciences,
Год журнала:
2024,
Номер
16(Suppl 2), С. S1204 - S1206
Опубликована: Апрель 1, 2024
A
BSTRACT
Delayed
wound
healing
is
one
of
the
most
common
problems
associated
with
diabetic
patients.
There
are
several
factors
delayed
healing.
It
has
been
observed
that
if
not
cured
takes
a
long
time.
This
reason
researchers
engaged
in
developing
sustainable,
biodegradable,
biocompatible,
and
effective
wound-healing
dressings.
However,
it
traditional
bandages
have
drawbacks
such
as
allergies
less
efficiency
absorption
exudate.
To
fill
gap,
hydrogels
developed
recently
which
higher
capacity.
In
addition,
they
pose
slow
drug
release
properties.
Therefore,
present
study
was
conducted
to
prepare
an
promising
hydrogel
high
Journal of Biomaterials Applications,
Год журнала:
2024,
Номер
38(9), С. 943 - 956
Опубликована: Март 11, 2024
Bletilla
striata
polysaccharide
(BSP)
was
added
to
curdlan
form
a
blend
hydrogel
through
simple
heating-cooling
procedure
improve
the
hydrophilicity
and
healing
efficacy
of
curdlan-based
used
in
wound
healing.
We
explored
interplay
between
BSP
curdlan,
studied
how
concentration
affects
physical
properties
microstructures
hydrogels,
examined
biocompatibility
hydrogel.
It
proved
that
framework
primarily
formed
by
ordered
arranged
molecules,
with
uniformly
dispersed
intertwined
hydrogen
bonding.
This
effectively
improved
its
strengthened
microstructure.
Curdlan
found
be
compatible
BSP.
The
B3Cd3
(containing
1.5%
w/v)
identified
as
optimal
formulation
based
on
higher
water
adsorption,
retention,
thermal
stability
interconnected
microstructure,
thus
selected
for
further
research.
In
vitro
experiments
revealed
highest
cell
viability
L929
extracts
compared
those
single-component
(Cd).
vivo,
animal
studies
indicated
accelerated
control
group
improving
re-epithelialization
blood
vessel
regeneration.
On
Days
3
11,
therapeutic
benefits
exceeded
Cd
group,
no
significant
differences
were
observed
rates
B
groups
from
Day
7.
study
proves
enhances
properties,
well
proliferation,
B3Cd3,
exceptional
holds
potential
future
application
material
non-infected
Journal of Pharmacy And Bioallied Sciences,
Год журнала:
2024,
Номер
16(Suppl 2), С. S1201 - S1203
Опубликована: Апрель 1, 2024
Three-dimensional
polymeric
networks
called
hydrogels
have
drawn
a
lot
of
interest
in
variety
biomedical
applications
because
their
distinctive
qualities,
like
high
water
content
and
biocompatibility.
Hydrogels
can
be
strengthened
mechanically
become
more
stable
via
cross-linking.
In
this
study,
we
described
the
synthesis
characterization
cross-linked
hydrogel
made
polyethylene
glycol
(PEG)
capable
absorbing
drug.
The
was
created
by
using
polymerization
procedure
to
cross-link
PEG
chains.
order
allay
worry,
added
particular
functional
groups
matrix
that
had
strong
affinity
for
glutaraldehyde.
These
it
easier
excess
glutaraldehyde
absorbed
sequestered
inside
hydrogel,
lowering
its
cytotoxic
potential.
After
incubation
with
residual
concentration
solution
measured
assess
absorption
Journal of Pharmacy And Bioallied Sciences,
Год журнала:
2024,
Номер
16(Suppl 2), С. S1204 - S1206
Опубликована: Апрель 1, 2024
A
BSTRACT
Delayed
wound
healing
is
one
of
the
most
common
problems
associated
with
diabetic
patients.
There
are
several
factors
delayed
healing.
It
has
been
observed
that
if
not
cured
takes
a
long
time.
This
reason
researchers
engaged
in
developing
sustainable,
biodegradable,
biocompatible,
and
effective
wound-healing
dressings.
However,
it
traditional
bandages
have
drawbacks
such
as
allergies
less
efficiency
absorption
exudate.
To
fill
gap,
hydrogels
developed
recently
which
higher
capacity.
In
addition,
they
pose
slow
drug
release
properties.
Therefore,
present
study
was
conducted
to
prepare
an
promising
hydrogel
high
