Water Research, Год журнала: 2022, Номер 212, С. 118069 - 118069
Опубликована: Янв. 14, 2022
Язык: Английский
The Science of The Total Environment, Год журнала: 2021, Номер 804, С. 150060 - 150060
Опубликована: Сен. 8, 2021
Successful detection of SARS-COV-2 in wastewater suggests the potential utility wastewater-based epidemiology (WBE) for COVID-19 community surveillance. This systematic review aims to assess performance surveillance as early warning system transmission. A search was conducted PubMed, Medline, Embase and WBE Consortium Registry according PRISMA guidelines relevant articles published until 31st July 2021. Relevant data were extracted summarized. Quality each paper assessed using an assessment tool adapted from Bilotta et al.'s environmental science. Of 763 studies identified, 92 distributed across 34 countries shortlisted qualitative synthesis. total 26,197 samples collected between January 2020 May 2021 various locations serving population ranging 321 11,400,000 inhabitants. Overall sample positivity moderate at 29.2% all examined settings with spike (S) gene having maximum rate positive detections nucleocapsid (N) being most targeted. Wastewater signals preceded confirmed cases by up 63 days, 13 reporting before first detected community. At least 50 reported association viral load cases. While cannot replace large-scale diagnostic testing, it can complement clinical providing signs transmission more active public health responses. However, standardized validated methods are required along risk analysis modelling understand dynamics outbreaks.
Язык: Английский
Процитировано
179
FEMS Microbes, Год журнала: 2023, Номер 4
Опубликована: Янв. 1, 2023
Abstract A year since the declaration of global coronavirus disease 2019 (COVID-19) pandemic, there were over 110 million cases and 2.5 deaths. Learning from methods to track community spread other viruses such as poliovirus, environmental virologists those in wastewater-based epidemiology (WBE) field quickly adapted their existing detect SARS-CoV-2 RNA wastewater. Unlike COVID-19 case mortality data, was not a dashboard wastewater monitoring worldwide. This study provides 1-year review “COVIDPoops19” universities, sites, countries Methods assemble combined standard literature review, Google Form submissions, daily, social media keyword searches. Over 200 1400 55 with 59 dashboards monitored for RNA. However, primarily high-income (65%) less access this valuable tool low- middle-income (35%). Data widely shared publicly or accessible researchers further inform public health actions, perform meta-analysis, better coordinate, determine equitable distribution sites. For WBE be used its full potential during beyond, show us data.
Язык: Английский
Процитировано
166
medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2021, Номер unknown
Опубликована: Март 17, 2021
Abstract A year since the declaration of global coronavirus disease 2019 (COVID-19) pandemic there were over 110 million cases and 2.5 deaths. Learning from methods to track community spread other viruses such as poliovirus, environmental virologists those in wastewater based epidemiology (WBE) field quickly adapted their existing detect SARS-CoV-2 RNA wastewater. Unlike COVID-19 case mortality data, was not a dashboard monitoring worldwide. This study provides one review “COVIDPoops19” universities, sites, countries Methods assemble combined standard literature review, direct submissions, daily, social media keyword searches. Over 200 1,000 55 with 59 dashboards monitor for RNA. However, is primarily high-income (65%) less access this valuable tool low middle income (35%). Data are widely shared publicly or accessible researchers further inform public health actions, perform meta-analysis, better coordinate, determine equitable distribution sites. For WBE be used its full potential during beyond, show us data.
Язык: Английский
Процитировано
109
Clinical Microbiology Reviews, Год журнала: 2023, Номер 37(1)
Опубликована: Дек. 14, 2023
SUMMARY Wastewater-based surveillance (WBS) has undergone dramatic advancement in the context of coronavirus disease 2019 (COVID-19) pandemic. The power and potential this platform technology were rapidly realized when it became evident that not only did WBS-measured SARS-CoV-2 RNA correlate strongly with COVID-19 clinical within monitored populations but also, fact, functioned as a leading indicator. Teams from across globe innovated novel approaches by which wastewater could be collected diverse sewersheds ranging treatment plants (enabling community-level surveillance) to more granular locations including individual neighborhoods high-risk buildings such long-term care facilities (LTCF). Efficient processes enabled extraction concentration highly dilute matrix. Molecular genomic tools identify, quantify, characterize its various variants adapted programs applied these mixed environmental systems. Novel data-sharing allowed information mobilized made immediately available public health government decision-makers even public, enabling evidence-informed decision-making based on local dynamics. WBS since been recognized tool transformative potential, providing near-real-time cost-effective, objective, comprehensive, inclusive data changing prevalence measured analytes space time populations. However, consequence rapid innovation hundreds teams simultaneously, tremendous heterogeneity currently exists literature. This manuscript provides state-of-the-art review established details current work underway expanding scope other infectious targets.
Язык: Английский
Процитировано
51
Environmental Science and Pollution Research, Год журнала: 2023, Номер 30(21), С. 60473 - 60499
Опубликована: Апрель 10, 2023
Язык: Английский
Процитировано
48
International Journal of Environmental Research and Public Health, Год журнала: 2020, Номер 17(24), С. 9251 - 9251
Опубликована: Дек. 10, 2020
SARS-CoV-2 is the causative agent of current COVID-19 pandemic. Disease clinical manifestations range from asymptomatic to severe multiple organ damage. uses ACE2 as a cellular receptor, which abundantly expressed in small intestine, allowing viral replication gastrointestinal tract. Viral RNA has been detected stool patients and viable viruses had isolated some these samples. Thus, putative role fecal-oral transmission argued. shed human excreta further disposed sewerage or environment, poor basic sanitation settings. Wastewater-based epidemiology (WBE) valuable population level approach for monitoring pathogens successfully used different contexts. This review summarizes global experience on WBE distinct continents detection polluted surface water. The advantages concerns this strategy surveillance are discussed. Outcomes suggest that early warning alert helpful complementary tool subside public health response, tailor containment mitigation measures determine target populations testing. In settings, contaminated rivers could be alternatively source environmental surveillance.
Язык: Английский
Процитировано
102
Water, Год журнала: 2021, Номер 13(20), С. 2897 - 2897
Опубликована: Окт. 15, 2021
Wastewater-based epidemiology (WBE) is an approach that can be used to estimate COVID-19 prevalence in the population by detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA wastewater. As WBE uses pooled samples from study population, it inexpensive and non-invasive mass surveillance method compared individual testing. Thus, offers a good complement low- middle-income countries (LMICs) facing high costs of testing or social stigmatization, has huge potential monitor SARS-CoV-2 its variants curb global pandemic. The aim this review systematize current evidence about application infection LMICs, as well future potential. Among other parameters, size contributing fecal input wastewater important parameter for estimation. It easier back-calculate community with centralized systems, because there more accurate estimates catchment. However, management systems are often low quality (or even non-existent) which raises major concern ability implement approach. possible mobilize approach, if large areas divided into sub-areas, corresponding existing systems. In addition, strong coordination between stakeholders required estimating respective Nevertheless, further international efforts should leveraged strengthen sanitation infrastructures using lessons gathered pandemic prepared pandemics.
Язык: Английский
Процитировано
59
Environmental Science and Pollution Research, Год журнала: 2021, Номер 28(18), С. 22221 - 22240
Опубликована: Март 17, 2021
Transmission of novel coronavirus (SARS-CoV-2) in humans happens either through airway exposure to respiratory droplets from an infected patient or by touching the virus contaminated surface objects (fomites). Presence SARS-CoV-2 human feces and its passage sewage system is emerging concern for public health. Pieces evidence occurrence viral RNA municipal wastewater (sewage) systems have not only warned reinforcing treatment facilities but also suggest that these can be monitored get epidemiological data checking trend COVID-19 infection community. This review summarizes persistence with emphasis on possible water environment contamination. Monitoring via sewage-based epidemiology could deliver promising information regarding rate providing a valid complementary tool tracking diagnosing across communities. Tracking act as early warning alerting health authorities necessary actions. Given impracticality testing every citizen limited diagnostic resources, it imperative tested system. The need development robust sampling strategies subsequent detection methodologies challenges developing countries are discussed.
Язык: Английский
Процитировано
58
The Science of The Total Environment, Год журнала: 2022, Номер 817, С. 152958 - 152958
Опубликована: Янв. 10, 2022
Язык: Английский
Процитировано
58
Water Research, Год журнала: 2022, Номер 223, С. 118904 - 118904
Опубликована: Июль 25, 2022
Язык: Английский
Процитировано
48