Microbial Biotechnology,
Год журнала:
2024,
Номер
17(10)
Опубликована: Окт. 1, 2024
Classical
epidemiology
relies
on
incidence,
mortality
rates,
and
clinical
data
from
individual
testing,
which
can
be
challenging
for
many
countries.
Therefore,
innovative,
flexible,
cost-effective,
scalable
surveillance
techniques
are
needed.
Wastewater-based
(WBE)
has
emerged
as
a
highly
powerful
tool
in
this
regard.
WBE
analyses
substances
excreted
human
fluids
faeces
that
enter
the
sewer
system.
This
approach
provides
insights
into
community
health
status
lifestyle
habits.
serves
an
early
warning
system
viral
surveillance,
detecting
emergence
of
new
pathogens,
changes
incidence
identifying
future
trends,
studying
outbreaks,
informing
performance
action
plans.
While
long
been
used
to
study
different
viruses
such
poliovirus
norovirus,
its
implementation
surged
due
pandemic
caused
by
Severe
Acute
Respiratory
Syndrome
Coronavirus
2.
led
establishment
wastewater
programmes
at
international,
national,
levels,
remain
operational.
Furthermore,
is
increasingly
applied
other
including
antibiotic
resistance
bacteria,
parasites,
fungi,
emerging
viruses,
with
methodologies
being
developed.
Consequently,
primary
focus
now
creating
international
frameworks
enhance
states'
preparedness
against
risks.
However,
there
remains
considerable
work
done,
particularly
integrating
principles
One
Health
epidemiological
acknowledge
interconnectedness
humans,
animals,
environment
pathogen
transmission.
Thus,
broader
analysing
three
pillars
must
developed,
transitioning
environmental
establishing
routine
practice
public
health.
ISME Communications,
Год журнала:
2022,
Номер
2(1)
Опубликована: Окт. 30, 2022
The
human
population
has
doubled
in
the
last
50
years
from
about
3.7
billion
to
approximately
7.8
billion.
With
this
rapid
expansion,
more
people
live
close
contact
with
wildlife,
livestock,
and
pets,
which
turn
creates
increasing
opportunities
for
zoonotic
diseases
pass
between
animals
people.
At
present
an
estimated
75%
of
all
emerging
virus-associated
infectious
possess
a
origin,
outbreaks
Zika,
Ebola
COVID-19
past
decade
showed
their
huge
disruptive
potential
on
global
economy.
Here,
we
describe
how
One
Health
inspired
environmental
surveillance
campaigns
have
emerged
as
preferred
tools
monitor
human-adjacent
environments
known
yet
be
discovered
diseases,
they
can
complement
classical
clinical
diagnostics.
We
highlight
importance
factors
concerning
interactions
animals,
pathogens
and/or
humans
that
drive
emergence
zoonoses,
methodologies
currently
proposed
them-the
wastewater,
example,
was
identified
one
main
assess
spread
SARS-CoV-2
by
public
health
professionals
policy
makers
during
pandemic.
One-Health
driven
approaches
facilitate
surveillance,
thus
harbour
preparing
humanity
future
pandemics
caused
aetiological
agents
reservoirs.
Via
example
other
viral
propose
wastewater
is
useful
diagnosis
it
centralized,
robust,
cost-effective,
relatively
easy
implement.
Environmental Science & Technology Letters,
Год журнала:
2023,
Номер
11(1), С. 9 - 15
Опубликована: Дек. 11, 2023
Climate
change
and
urbanization
are
increasing
the
distribution
of
insect
vectors
infectious
diseases.
Dengue
virus
is
an
arbovirus
that
causes
nearly
100
million
symptomatic
infections
per
year
endemic
in
124
countries,
range
its
mosquito
continues
to
increase.
Surveillance
dengue
complicated
by
fact
can
be
asymptomatic,
symptoms
may
not
readily
recognizable
clinicians.
Here
we
show
wastewater
monitoring
used
detect
RNA
yield
information
about
circulation
a
community.
We
collected
three
samples
solids
week
from
different
treatment
plants
Miami-Dade
County,
Florida,
where
were
locally
acquired.
Using
molecular
methods,
tested
for
4
serotypes
consistently
detected
3
at
all
did
other
serotypes.
According
publicly
available
data
on
infections,
vast
majority
caused
serotype
3.
Wastewater
detection
possible
with
as
few
4.23
laboratory
confirmed
cases
1
people
based
infection
data.
The Lancet Microbe,
Год журнала:
2024,
Номер
unknown, С. 100939 - 100939
Опубликована: Авг. 1, 2024
SummaryWastewater
surveillance
holds
great
promise
as
a
sensitive
method
to
detect
spillover
of
zoonotic
infections
and
early
pandemic
emergence,
thereby
informing
risk
mitigation
public
health
response.
Known
viruses
with
potential
are
shed
in
human
stool
or
urine,
both,
the
experiences
SARS-CoV-2,
monkeypox
virus,
Zika
virus
highlight
feasibility
community-based
wastewater
for
that
have
different
transmission
routes.
We
reviewed
shedding
data
prototype
representing
viral
families
concern
estimate
likely
sensitivity
compared
clinical
surveillance.
examined
how
on
detection,
together
genetic
sequences
animal
faecal
biomarkers,
could
be
used
identify
adaptation.
The
opportunities
challenges
associated
global
prevention
pandemics
described
this
Personal
View,
focusing
low-income
middle-income
countries,
where
emergence
is
highest.
propose
research
agenda
ensure
an
equitable
sustainable
solution
these
challenges.
EBioMedicine,
Год журнала:
2024,
Номер
101, С. 105020 - 105020
Опубликована: Фев. 21, 2024
In
June
2023,
a
local
cluster
of
15
Zika
cases
was
reported
in
neighbourhood
Northeastern
Singapore.
The
last
significant
transmission
virus
(ZIKV)
with
more
than
450
2016-2017.
To
monitor
the
situation
and
mitigate
further
transmission,
case,
entomological
wastewater-based
surveillance
were
carried
out.
Journal of Virology,
Год журнала:
2024,
Номер
98(2)
Опубликована: Янв. 16, 2024
Fast
detection
and
rapid
intervention
are
crucial
to
mitigate
risks
of
pathogen
emergence,
spillover
spread—every
second
counts.
However,
comprehensive,
active,
longitudinal
surveillance
systems
at
high-risk
interfaces
that
provide
real-time
data
for
action
remain
lacking.
This
paper
proposes
"smart
market"
harnessing
cutting-edge
tools
a
range
sampling
techniques,
including
wastewater
air
collection,
multiplex
assays,
metagenomic
sequencing.
Coupled
with
robust
response
pathways,
these
could
better
enable
Early
Warning
bolster
prevention
efforts.
Environmental Pollution,
Год журнала:
2024,
Номер
351, С. 124045 - 124045
Опубликована: Апрель 25, 2024
In
the
face
of
emerging
and
re-emerging
diseases,
novel
innovative
approaches
to
population
scale
surveillance
are
necessary
for
early
detection
quantification
pathogens.
The
last
decade
has
seen
rapid
development
wastewater
environmental
(WES)
address
public
health
challenges,
which
led
establishment
wastewater-based
epidemiology
(WBE)
being
deployed
monitor
a
range
hazards.
WBE
exploits
fact
that
excretions
secretions
from
urine,
gut
discharged
in
wastewater,
particularly
sewage,
such
sampling
sewage
systems
provides
an
warning
system
disease
outbreaks
by
providing
indication
pathogen
circulation.
While
been
mainly
used
locations
with
networked
systems,
here
we
consider
its
value
less
connected
populations
typical
lower-income
settings,
assess
opportunity
afforded
pit
latrines
sample
communities
localities.
We
propose
where
struggle
access
diagnostic
facilities,
despite
several
additional
unconnected
remains
important
means
large
relatively
cost-effective
manner.
Heliyon,
Год журнала:
2024,
Номер
10(13), С. e33873 - e33873
Опубликована: Июнь 29, 2024
A
focus
on
water
quality
has
intensified
globally,
considering
its
critical
role
in
sustaining
life
and
ecosystems.
Wastewater,
reflecting
societal
development,
profoundly
impacts
public
health.
Wastewater-based
epidemiology
(WBE)
emerged
as
a
surveillance
tool
for
detecting
outbreaks
early,
monitoring
infectious
disease
trends,
providing
real-time
insights,
particularly
vulnerable
communities.
WBE
aids
tracking
pathogens,
including
viruses,
sewage,
offering
comprehensive
understanding
of
community
health
lifestyle
habits.
With
the
rise
global
COVID-19
cases,
gained
prominence,
aiding
SARS-CoV-2
levels
worldwide.
Despite
advancements
treatment,
poorly
treated
wastewater
discharge
remains
threat,
amplifying
spread
water-,
sanitation-,
hygiene
(WaSH)-related
diseases.
WBE,
serving
complementary
surveillance,
is
pivotal
community-level
viral
infections.
However,
there
untapped
potential
to
expand
surveillance.
This
review
emphasizes
importance
link
between
health,
highlighting
need
further
integration
into
management.
