Synthesis and Characterization of Zirconium Dioxide Nanoparticles in Various Liquid Media by Nd:YAG Pulse Laser Ablation and Its Antibacterial Application DOI Creative Commons

Dwi Endah Ni’matul Amalia,

Iis Nurhasanah, Ali Khumaeni

и другие.

Jurnal Kimia Sains dan Aplikasi, Год журнала: 2024, Номер 27(10), С. 464 - 469

Опубликована: Сен. 23, 2024

The issue of antibiotic resistance by bacteria has been studied to develop a new agent inhibit bacterial activity. Recent studies have reported on nanoparticles promising antibacterial properties. Zirconium dioxide (ZrO2 NPs) emerged as potential agents for gram-negative bacteria. Nevertheless, there remains gap in research done producing stable nanoparticles. Additionally, it the impact liquid environment synthesis keep small size. In this present work, ZrO2 NPs successfully synthesized various liquids pulse laser ablation using Nd:YAG laser. was ablated surface zirconium metal plate different media, such deionized water, ethylene diamine, and chitosan solution. Furthermore, media used an effect characteristics their An investigation scanning electron microscope images reveals that solutions spherical morphology with diameters measuring around 24.33 nm, 19.76 15.05 respectively. solution against E. coli is assessed diameter inhibition zone (DIZ), which greater colloidal stability than other media. findings indicate size enhance ability growth

Язык: Английский

Enrofloxacin‑silver composite nano-emulsion as a scalable synergetic antibacterial platform for accelerating infected wound healing DOI Creative Commons

Jiahao Gong,

Moxin Liu,

Runan Zuo

и другие.

International Journal of Pharmaceutics X, Год журнала: 2025, Номер unknown, С. 100330 - 100330

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Synthesis, characterization and evaluation of in vitro potential antimicrobial efficiency of new chitosan hydrogels and their CuO nanocomposites DOI
Nadia A. Mohamed

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 276, С. 133810 - 133810

Опубликована: Июль 14, 2024

Язык: Английский

Процитировано

3

Green Synthesis and Characterization of Apple Peel‐Derived Selenium Nanoparticles for Anti‐Fungal Activity and Effects of MexA Gene Expression on Efflux Pumps in Acinetobacter baumannii DOI
Mais E. Ahmed, Ghassan M. Sulaiman,

Buthenia A. Hasoon

и другие.

Applied Organometallic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Окт. 8, 2024

ABSTRACT Selenium nanoparticles (Se‐NPs) were produced adopting an environmentally benign green synthetic approach from the waste biomaterial obtained apple peel extract (APE). The NPs characterized through UV–Visible spectroscopy (UV–Vis), atomic force microscopy (AFM), Fourier‐transform infrared (FT‐IR), X‐ray diffraction (XRD), field emission‐scanning electron (FE‐SEM), and transmission (TEM). spectra exhibited absorption peak λ max at 295 nm, confirming formation of Se‐NPs. AFM examination revealed roughness distribution nanoparticles, FT‐IR ascertained surface‐contained functional groups presence. XRD confirmed crystalline nature sample, FE‐SEM validated surface morphology size range 52 to 84 nm. TEM demonstrated spherical shapes Se‐NPs with a face‐centered cubic crystal nature, whereas analysis showed mean 70 minimum inhibitory concentration (MIC) 500 μg mL −1 against Candida spp ., namely, C. albicans , guilliermondii ciferrii their anti‐fungal activity in control minor statistical difference ( p < 0.05) dissemination zones inhibition for treatment these fungi. effects on MexA gene expression efflux pump role gene's down regulation treated fungal strains. multi‐drug resistant microbes.

Язык: Английский

Процитировано

3

Enhanced anti-microbial activity of ofloxacin-loaded mesoporous silica nanoparticles against clinical isolates of drug-resistant microbes DOI

M. Shariq Ahmed,

Nehia N. Hussein, Ghassan M. Sulaiman

и другие.

Journal of Industrial and Engineering Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Chitosan‐Coated Gold Nanoparticles' Folic Acid Conjugates for Targeted Delivery of Papain Enzyme: An Extended Nanoplatform Approach for Cancer Therapy DOI Open Access

Fatima R. Dayekh,

Ghassan M. Sulaiman, Hamdoon A. Mohammed

и другие.

Applied Organometallic Chemistry, Год журнала: 2025, Номер 39(4)

Опубликована: Март 3, 2025

ABSTRACT Cancer is a significant global public health concern, being the second leading cause of mortality, accounting for one in six cases worldwide. Researchers have employed various approaches cancer treatment, with nanobiotechnology emerging as standout technique developing anticancer agents. This study assessed activity chitosan (CS)‐coated gold nanoparticles (AuNPs) and combination AuNPs–papain (Pap)–folic acid (FA) nanomaterial platforms against Michigan Foundation‐7 (MCF‐7) cell lines. A range methods, including ultraviolet–visible (UV–Vis), Fourier transform infrared (FTIR), scanning electron microscopy (SEM), transmission (TEM), X‐ray diffraction (XRD), energy‐dispersive spectroscopy (EDS), zeta potential, were used to characterize prepared nanomaterials. AuNPs AuNPs–Pap–FA exhibited UV–Vis absorption at 525 558 nm, respectively. In XRD test, peaks found 32°, 39°, 45°, 65°, 78.5°, AuNPs–CS–Pap–FA identified 29, 37°, 78.5°. SEM revealed irregularly dispensed oval shapes AuNPs. TEM images confirmed shape before after coating Pap FA. The mean diameter was 15 AuNPs–CS–Pap–FA, it 22.5 nm. Acridine orange–ethidium bromide (AO/EB) staining, flow cytometry assay, 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH), vitro hemolysis assays conducted. maximum scavenging observed reaching up 90%. hemolytic rate low concentrations (3.12, 6.25, 12.5 μg mL −1 ) within permissible levels. concentration 100 reduced viability MCF‐7 cells 10% when compared nontreated cells. highest expression caspase‐8 achieved treating line AuNPs–CS–Pap–FA. nanopreparation remarkable holds promise potential candidate further development towards clinical applications an agent.

Язык: Английский

Процитировано

0

Resveratrol-Functionalized Gold Nanoparticles: A Promising Approach to Inhibit Biofilm Formation and Suppress Type III Secretion System Gene Expression in Pseudomonas aeruginosa Clinical Isolates DOI

Alireza Habibi,

Seyed Ataollah Sadat Shandiz, Reza Kazemi Darsanaki

и другие.

BioNanoScience, Год журнала: 2025, Номер 15(3)

Опубликована: Май 21, 2025

Язык: Английский

Процитировано

0

Reducing the effective dose of doxycycline using chitosan silver nanocomposite as a carriers on gram positive and gram-negative bacteria DOI Creative Commons

Elham M. Mostafa,

Y. Badr,

M. M. Hashem

и другие.

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Ноя. 13, 2024

Abstract Doxycycline (Doxy) is a tetracycline antibiotic with potent antibacterial activity against broad range of bacteria. Using nanotechnology one feasible way to increase the antibiotics’ ability penetrate body and their effectiveness. In this work, we report formation stable green synthesized silver nanoparticles (AgNPs) by chitosan Doxy nanocomposite for first time. The obtained were characterized transmission electron microscopy (TEM), zeta-potential, UV-Visible spectroscopy four transform infrared (FTIRs). effect doxy, AgNPs doxy/AgNPs determined on Gram-positive Staphylococcus aureus , Streptococcus mutans Gram-negative Escherichia coli Klebsiella pneumonia . This combined therapeutic agent restored susceptibility doxy showed an tested has absorption peak at 445 nm, mixing causes all absorptions red shift broadening in surface plasmon resonance (SPR) show slight particle size from 12 ± 2 nm 14 high stability as zeta potential was 29 mv 48.5mv Doxy/AgNPs respectively. found be twice free suggesting synergistic interaction between two components. conclusion, synergy quite promising resistant strains. These results highlight boost efficacy doxycycline.

Язык: Английский

Процитировано

2

Bio-Inspired Synthesis of Gold Nanoparticles Using Leaf Extract of Jamun and Research on Its Biomedical Potential DOI Creative Commons
Gitishree Das, Han‐Seung Shin,

K.Y. Lim

и другие.

International Journal of Nanomedicine, Год журнала: 2024, Номер Volume 19, С. 12257 - 12286

Опубликована: Ноя. 1, 2024

Bio-based synthesis of metallic nanoparticles has garnered much attention in recent times owing to their non-toxic, environmentally friendly, and cost-effective nature.

Язык: Английский

Процитировано

2

Promising antibiofilm formation: Liquid phase pulsed laser ablation synthesis of Graphene Oxide@Platinum core-shell nanoparticles DOI Creative Commons

Buthenia A. Hasoon,

Dahlia Mohammed Ali Hasan, Kareem H Jawad

и другие.

PLoS ONE, Год журнала: 2024, Номер 19(9), С. e0310997 - e0310997

Опубликована: Сен. 24, 2024

The increasing prevalence of multi-drug resistance in pathogenic bacteria has rendered antibiotics ineffective, necessitating the exploration alternative antibacterial approaches. Consequently, research efforts have shifted towards developing new and improving efficacy existing ones. In present study, novel core shell graphene oxide@platinum nanoparticles (GRO@Pt-NPs) their unchanging form been synthesized using two-step pulsed laser ablation liquid (PLAL) technique. first step involved target to create (GRO-NPs), followed by GRO-NPs inside platinum (Pt-NPs). To characterize nanoparticles, various methods were employed, including UV-VIS, transmission electron microscopy (TEM), energy dispersive X-ray (EDX), mapping tests, diffraction (XRD). anti-bacterial anti-biofilm properties investigated. TEM data confirm creation GRO@Pt-NPs. average particle size was 11 nm for GRO-NPs, 14 Pt-NPs, 26 results demonstrate that created GRO@Pt-NPs strong properties. This pattern is mostly produced through accumulation on bacterial surface Klebsiella pneumoniae ( K . ) Enterococcus faecium E ). inhibition zones against when used alone found be 11.80 mm 11.50 mm, respectively. For 20.50 16.50 utilization resulted a significant increase these values, with inhibitory rates 25.50 20.45 more potent core–shell structure than or Pt-NPs alone. current work uses, time, fast effective technique synthesize PLAL method, preparation high clinical potential prospective use as an agent.

Язык: Английский

Процитировано

1

Biosynthesis of Platinum Nanoparticles: Evaluation of Their Activity Against Streptococcus mutans and In Silico Study DOI

Rusul Hamd Sami,

Sabrean Farhan Jawad,

Faeza H. Zankanah

и другие.

Plasmonics, Год журнала: 2024, Номер unknown

Опубликована: Сен. 28, 2024

Язык: Английский

Процитировано

1