Jurnal Kimia Sains dan Aplikasi,
Journal Year:
2024,
Volume and Issue:
27(10), P. 464 - 469
Published: Sept. 23, 2024
The
issue
of
antibiotic
resistance
by
bacteria
has
been
studied
to
develop
a
new
agent
inhibit
bacterial
activity.
Recent
studies
have
reported
on
nanoparticles
promising
antibacterial
properties.
Zirconium
dioxide
(ZrO2
NPs)
emerged
as
potential
agents
for
gram-negative
bacteria.
Nevertheless,
there
remains
gap
in
research
done
producing
stable
nanoparticles.
Additionally,
it
the
impact
liquid
environment
synthesis
keep
small
size.
In
this
present
work,
ZrO2
NPs
successfully
synthesized
various
liquids
pulse
laser
ablation
using
Nd:YAG
laser.
was
ablated
surface
zirconium
metal
plate
different
media,
such
deionized
water,
ethylene
diamine,
and
chitosan
solution.
Furthermore,
media
used
an
effect
characteristics
their
An
investigation
scanning
electron
microscope
images
reveals
that
solutions
spherical
morphology
with
diameters
measuring
around
24.33
nm,
19.76
15.05
respectively.
solution
against
E.
coli
is
assessed
diameter
inhibition
zone
(DIZ),
which
greater
colloidal
stability
than
other
media.
findings
indicate
size
enhance
ability
growth
Applied Organometallic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 8, 2024
ABSTRACT
Selenium
nanoparticles
(Se‐NPs)
were
produced
adopting
an
environmentally
benign
green
synthetic
approach
from
the
waste
biomaterial
obtained
apple
peel
extract
(APE).
The
NPs
characterized
through
UV–Visible
spectroscopy
(UV–Vis),
atomic
force
microscopy
(AFM),
Fourier‐transform
infrared
(FT‐IR),
X‐ray
diffraction
(XRD),
field
emission‐scanning
electron
(FE‐SEM),
and
transmission
(TEM).
spectra
exhibited
absorption
peak
λ
max
at
295
nm,
confirming
formation
of
Se‐NPs.
AFM
examination
revealed
roughness
distribution
nanoparticles,
FT‐IR
ascertained
surface‐contained
functional
groups
presence.
XRD
confirmed
crystalline
nature
sample,
FE‐SEM
validated
surface
morphology
size
range
52
to
84
nm.
TEM
demonstrated
spherical
shapes
Se‐NPs
with
a
face‐centered
cubic
crystal
nature,
whereas
analysis
showed
mean
70
minimum
inhibitory
concentration
(MIC)
500
μg
mL
−1
against
Candida
spp
.,
namely,
C.
albicans
,
guilliermondii
ciferrii
their
anti‐fungal
activity
in
control
minor
statistical
difference
(
p
<
0.05)
dissemination
zones
inhibition
for
treatment
these
fungi.
effects
on
MexA
gene
expression
efflux
pump
role
gene's
down
regulation
treated
fungal
strains.
multi‐drug
resistant
microbes.
Nanomaterials,
Journal Year:
2024,
Volume and Issue:
14(22), P. 1854 - 1854
Published: Nov. 20, 2024
Gold
nanoparticles
(NPs)
have
demonstrated
significance
in
several
important
fields,
including
drug
delivery
and
anticancer
research,
due
to
their
unique
properties.
NPs
possess
significant
optical
characteristics
that
enhance
application
biosensor
development
for
diagnosis,
photothermal
photodynamic
therapies
treatment,
targeted
bioimaging.
The
broad
surface
modification
possibilities
of
gold
been
utilized
the
various
molecules,
nucleic
acids,
drugs,
proteins.
Moreover,
strong
localized
plasmon
resonance
(LSPR)
properties,
facilitating
use
surface-enhanced
Raman
scattering
precise
efficient
biomolecule
detection.
These
properties
are
extensively
research.
Both
show
results
treatments
using
NPs.
Additionally,
demonstrate
potential
other
biological
areas,
particularly
antimicrobial
activity.
In
addition
delivering
antigens,
peptides,
antibiotics
activity,
can
penetrate
cell
membranes
induce
apoptosis
through
intracellular
mechanisms.
Among
types
metal
NPs,
more
tolerable
toxicity
capacity,
supporting
wide-ranging
areas.
hold
a
special
position
nanomaterial
offering
limited
This
review
aims
address
recently
highlighted
applications
current
status
NP
research
discuss
future
nanomedicine.
Green Processing and Synthesis,
Journal Year:
2024,
Volume and Issue:
13(1)
Published: Jan. 1, 2024
Abstract
The
utilization
of
plant
bioactive
composites
has
concerned
substantial
attention
due
to
their
possible
use
in
the
development
novel
antibiotics,
containing
environmentally
sustainable
synthesis
nanoparticles.
In
current
study,
a
green
and
eco-friendly
process
was
employed
synthesize
silver
nanoparticles
(Ag-NPs)
evaluate
anti-bacterial,
anti-oxidant,
anti-cancer
potentials.
characterization
Ag-NPs
involved
UV-vis
spectroscopy,
Fourier-transform
infrared
spectroscopy
(FTIR),
energy-dispersive
X-ray
(EDX),
diffraction
(XRD),
field
emission
scanning
electron
microscopy
(FESEM),
transmission
(TEM).
spectrum
437
nm.
FTIR
absorption
peaks
detected
at
685.48
cm
−1
confirmed
characteristics.
FESEM
displayed
that
have
an
average
size
30
TEM
revealed
irregular
spherical
shape
with
16
nm
distribution.
XRD
results
provided
strong
indication
synthesized
high
purity
crystalline
nature.
anti-bacterial
properties
were
investigated
different
concentrations
for
both
ethanolic
tangerine
peel
extract
Ag-NPs.
activity
showed
100
µg·mL
potent
concentration,
but
more
effective
than
extract.
For
extract,
inhibition
zone
17.50
±
0.20
mm
K.
pneumoniae
14.40
B.
cereus
.
Ag-NPs,
25.50
20.50
cereus.
Furthermore,
antioxidant
examination
free
radical
scavenging
alone.
ranged
46–77%
while
57–88%.
Additionally,
anti-proliferative
against
lung
cancer
cell
line
(A549)
cytotoxic
90.03%
78.50%,
respectively.
effect
is
attributed
death,
induced
apoptosis,
enhanced
generation
reactive
oxygen
species.
Our
findings
highlight
potential
further
medicinal
applications
particularly
therapeutics.
PLoS ONE,
Journal Year:
2024,
Volume and Issue:
19(9), P. e0310997 - e0310997
Published: Sept. 24, 2024
The
increasing
prevalence
of
multi-drug
resistance
in
pathogenic
bacteria
has
rendered
antibiotics
ineffective,
necessitating
the
exploration
alternative
antibacterial
approaches.
Consequently,
research
efforts
have
shifted
towards
developing
new
and
improving
efficacy
existing
ones.
In
present
study,
novel
core
shell
graphene
oxide@platinum
nanoparticles
(GRO@Pt-NPs)
their
unchanging
form
been
synthesized
using
two-step
pulsed
laser
ablation
liquid
(PLAL)
technique.
first
step
involved
target
to
create
(GRO-NPs),
followed
by
GRO-NPs
inside
platinum
(Pt-NPs).
To
characterize
nanoparticles,
various
methods
were
employed,
including
UV-VIS,
transmission
electron
microscopy
(TEM),
energy
dispersive
X-ray
(EDX),
mapping
tests,
diffraction
(XRD).
anti-bacterial
anti-biofilm
properties
investigated.
TEM
data
confirm
creation
GRO@Pt-NPs.
average
particle
size
was
11
nm
for
GRO-NPs,
14
Pt-NPs,
26
results
demonstrate
that
created
GRO@Pt-NPs
strong
properties.
This
pattern
is
mostly
produced
through
accumulation
on
bacterial
surface
Klebsiella
pneumoniae
(
K
.
)
Enterococcus
faecium
E
).
inhibition
zones
against
when
used
alone
found
be
11.80
mm
11.50
mm,
respectively.
For
20.50
16.50
utilization
resulted
a
significant
increase
these
values,
with
inhibitory
rates
25.50
20.45
more
potent
core–shell
structure
than
or
Pt-NPs
alone.
current
work
uses,
time,
fast
effective
technique
synthesize
PLAL
method,
preparation
high
clinical
potential
prospective
use
as
an
agent.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Nov. 13, 2024
Abstract
Doxycycline
(Doxy)
is
a
tetracycline
antibiotic
with
potent
antibacterial
activity
against
broad
range
of
bacteria.
Using
nanotechnology
one
feasible
way
to
increase
the
antibiotics’
ability
penetrate
body
and
their
effectiveness.
In
this
work,
we
report
formation
stable
green
synthesized
silver
nanoparticles
(AgNPs)
by
chitosan
Doxy
nanocomposite
for
first
time.
The
obtained
were
characterized
transmission
electron
microscopy
(TEM),
zeta-potential,
UV-Visible
spectroscopy
four
transform
infrared
(FTIRs).
effect
doxy,
AgNPs
doxy/AgNPs
determined
on
Gram-positive
Staphylococcus
aureus
,
Streptococcus
mutans
Gram-negative
Escherichia
coli
Klebsiella
pneumonia
.
This
combined
therapeutic
agent
restored
susceptibility
doxy
showed
an
tested
has
absorption
peak
at
445
nm,
mixing
causes
all
absorptions
red
shift
broadening
in
surface
plasmon
resonance
(SPR)
show
slight
particle
size
from
12
±
2
nm
14
high
stability
as
zeta
potential
was
29
mv
48.5mv
Doxy/AgNPs
respectively.
found
be
twice
free
suggesting
synergistic
interaction
between
two
components.
conclusion,
synergy
quite
promising
resistant
strains.
These
results
highlight
boost
efficacy
doxycycline.
International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 12257 - 12286
Published: Nov. 1, 2024
Bio-based
synthesis
of
metallic
nanoparticles
has
garnered
much
attention
in
recent
times
owing
to
their
non-toxic,
environmentally
friendly,
and
cost-effective
nature.
