International Journal of Behavioral Nutrition and Physical Activity, Год журнала: 2024, Номер 21(1)
Опубликована: Сен. 26, 2024
Язык: Английский
American Journal of Clinical Nutrition, Год журнала: 2023, Номер 119(1), С. 206 - 220
Опубликована: Окт. 20, 2023
Язык: Английский
Процитировано
16
Cell Reports, Год журнала: 2024, Номер 43(8), С. 114523 - 114523
Опубликована: Июль 23, 2024
Язык: Английский
Процитировано
5
Reviews in Endocrine and Metabolic Disorders, Год журнала: 2023, Номер 25(2), С. 325 - 337
Опубликована: Ноя. 22, 2023
Abstract Daily rhythms of metabolic function are supported by molecular circadian clock systems that strongly regulated feeding and fasting. Intermittent fasting diets have been associated with weight loss improved metabolism. However, the effects time-restricted eating (TRE) on glycemic parameters still under debate. In this review, we aim to systematically analyze TRE parameters. We searched PubMed, EMBASE, Cochrane Library for controlled studies in which subjects followed at least 4 weeks. 20 were included qualitative systematic 18 (n = 1169 subjects) meta-analysis. Overall, had no significant effect glucose (Hedges’s g -0.08; 95% CI:-0.31,0.16; p 0.52), but it did reduce HbA1c levels -0.27; CI: -0.47, -0.06; 0.01). significantly reduced insulin -0.40; -0.73,-0.08; 0.01) showed a tendency decrease HOMA-IR -0.32; CI:-0.66,0.02; 0.06). Interestingly, cumulative analysis beneficial regarding less apparent as later windows (lTRE) being included. Indeed, subgroup early (eTRE) revealed was eTRE -0.38; CI:-0.62, -0.14; < Our meta-analysis suggests can levels, timing food intake is crucial factor benefit TRE, only capable reducing overweight or obesity. PROSPERO registration number CRD42023405946.
Язык: Английский
Процитировано
11
Nutrients, Год журнала: 2024, Номер 16(11), С. 1721 - 1721
Опубликована: Май 31, 2024
Chrono-nutrition (meal timing) aligns food consumption with one’s circadian rhythm. The first meal (e.g., breakfast) likely promotes synchronization of peripheral clocks, thereby supporting metabolic health. Time-restricted feeding (TRF) has been shown to reduce body weight (BW) and/or improve cardiovascular biomarkers. In this explorative literature assessment, 13 TRF randomized controlled trials (RCTs) were selected from PubMed and Scopus evaluate the effects early (eTRF: before 10:30 a.m.) late (lTRF: after 11:30 on parameters Although distinct variations in study design evident between reports, consistently decreased energy intake (EI) BW, improved insulin resistance as well systolic blood pressure. eTRF seemed have a greater beneficial effect than lTRF (HOMA-IR). Importantly, most studies did not appear consider chronotype their evaluation, which may underestimated effects. intervention be promising approach for risk reduction human diseases. To conclusively determine benefits identify clear differences lTRF, future should longer-term (≥8 weeks) well-defined (differences in) windows, include participants chronotypically matching intervention, compare outcomes those control groups without any dietary limitations.
Язык: Английский
Процитировано
4
Nutrients, Год журнала: 2024, Номер 16(19), С. 3390 - 3390
Опубликована: Окт. 5, 2024
Time-restricted eating (TRE) is a circadian rhythm-based intermittent fasting intervention that has been used to treat obesity. However, the efficacy and safety of TRE for fat loss have not comprehensively examined influences characteristics on such effects are unknown. This systematic review meta-analysis characterized in adults with overweight obese, it explored influence this effect. A search strategy based PICOS principle was find relevant publications seven databases. The outcomes were body composition, anthropometric indicators, blood lipid metrics. Twenty (20 studies) 1288 participants, covering period from 2020 2024, included. Compared control group, safely significantly reduced percentage, mass, lean BMI, waist circumference (MDpooled = -2.14 cm, 95% CI -2.88~-1.40, p < 0.001), increased low-density lipoprotein (LDL) 2.70, 0.17~5.22, 0.037), but did alter total cholesterol, high-density lipoprotein, triglycerides -1.09~1.20 mg/dL, -4.31~5.47, > 0.05). Subgroup analyses showed only or TRE-caloric restriction an window 6 8 h may be appropriate losing overall weight. work provides moderate high evidence promising dietary loss. Although potentially reduce mass increase LDL, these do pose significant concerns. trial registered PROSPERO as CRD42023406329.
Язык: Английский
Процитировано
4
Nutrition & Metabolism, Год журнала: 2025, Номер 22(1)
Опубликована: Янв. 6, 2025
Intermittent fasting (IF) can be an effective dietary therapy for weight loss and improving cardiometabolic health. However, there is scant evidence regarding the role of IF on indicators liver function, particularly in adults with metabolic disorders. Therefore, we performed a systematic review meta-analysis to investigate effects function Three primary electronic databases including PubMed, Web Science, Scopus, were searched from inception September 2024 identify original studies that used interventions or without control groups Inclusion criteria (1) human participants diseases, (2) evaluated IF, (3) group, (4) measured fat, steatosis, fibrosis, enzymes, alanine aminotransferase (ALT) aspartate (AST) as outcomes. Standardized mean differences (SMD) 95% confidence intervals calculated using random models. Heterogeneity was assessed Cochran's Q statistic I-squared (I2). Publication bias visual inspection funnel plots Egger's tests. The risk PEDro scale NIH quality assessment tool. A total 21 involving 1,226 disorders included meta-analysis. Overall, effectively decreased fat large effect size [SMD: -1.22 (95% CI: -1.63 -0.80), p = 0.001], steatosis medium -0.73 -1.12 -0.35), ALT small -0.44 -0.58 -0.30), AST -0.30 -0.49 -0.11), but not fibrosis -0.28 -0.59 0.02), 0.07]. Subgroup analyses showed significantly, independent mode, participant age, health status, intervention duration. significantly those obesity; following 5:2 diets, middle-aged adults, obesity, regardless status seems disorders, many function-related benefits occur duration, status. Significant heterogeneity, numbers inclusion non-randomized trials single-group pre-post main limitation our Further randomized clinical are needed elucidate
Язык: Английский
Процитировано
0
Nature Medicine, Год журнала: 2025, Номер unknown
Опубликована: Янв. 28, 2025
Язык: Английский
Процитировано
0
Experimental and Clinical Gastroenterology, Год журнала: 2025, Номер 9, С. 26 - 35
Опубликована: Март 6, 2025
The purpose of this study is to present the results a comparative assessment effect intermittent restricted diet (ICR) with constant (CCR) on weight loss, fat mass, cardiometabolic risk markers, glucose and insulin levels in obese adults. Materials methods: works cited were selected using keywords “obesity”, “comorbidity”, “weight loss”, “intermittent calorie restriction”, “constant search engines PubMed, Scopus. Publications had meet following criteria: randomized clinical trials, published last decade (2014-2024), access full text publication, primary endpoint or continuous restriction as main intervention, adult population, subjects obesity comorbid pathology. Results: Obesity has acquired pandemic proportions worldwide. In some countries, prevalence rates range from 20 40%. Prevalence incidence continue increase. It estimated that by 2030, almost 50% world’s population will be overweight obese. increases number chronic noncommunicable diseases (T2DM, CVD, CKD, CLD, types cancer). Weight loss intervention for people obesity. Conservative non-drug therapy form nutritional modification mainstay treatment recommended first, mandatory permanent component treatment. Daily caloric feeding are two forms dietary can help reduce body weight. Conclusion: Based analysis, we concluded ICR CCR alternative energy regimens comparable improvements obesity-related markers. Both well tolerated most studies may equivalent approaches loss. Further needed examine efficacy, feasibility safety patients such type 2 diabetes, cardiovascular disease cancer.
Язык: Английский
Процитировано
0
Nutrition Research, Год журнала: 2025, Номер unknown
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Journal of Health Population and Nutrition, Год журнала: 2025, Номер 44(1)
Опубликована: Апрель 2, 2025
Язык: Английский
Процитировано
0