Silymarin: A Natural Compound for Obesity Management

Obesities, Год журнала: 2024, Номер 4(3), С. 292 - 313

Опубликована: Авг. 9, 2024

Silybum marianum (L.) Gaertn, commonly known as milk thistle, is an herbal medicine rich in silymarin, a bioflavonoid complex. Historically, silymarin was used for treating liver diseases, but recent studies highlight silymarin’s potential obesity management. This narrative review aims to provide in-depth examination of the existing knowledge and its secondary compounds concerning associated comorbidities, summarizing data from vitro, preclinical, clinical studies. Obesity significant public health issue, exacerbated during COVID-19 pandemic, major risk factor mortality. It contributes metabolic dysfunction, including oxidative stress, metainflammation, cardiovascular type 2 diabetes development. Silymarin has demonstrated benefits on insulin signaling lipid metabolism, well antioxidant anti-inflammatory properties at molecular level. Innovative also suggest prebiotic, positively influencing gut microbiota composition, key affected by obesity. These promising findings support anti-obesity action practice. Looking forward, using innovative complementary therapy could offer substantial natural promotion Nevertheless, further research into optimal doses cellular mechanisms still needed.

Язык: Английский

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Theabrownin, gut microbiota, and obesity: Effects and mechanisms

Food Bioscience, Год журнала: 2024, Номер unknown, С. 105381 - 105381

Опубликована: Окт. 1, 2024

Язык: Английский

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Cu-Based Metal-Organic Framework Synthesized via Green Method Exhibits Unique Catecholase-Like Activity for Epigallocatechin Gallate Detection in Teas

Analytical Methods, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Tea contains various antioxidant compounds, including polyphenols, catechins, theaflavins, theasinensins, and flavonoids. Among these, epigallocatechin gallate (EGCG) is a crucial recognized for its potent bioactivity. This study presents the synthesis of highly selective Cu-PyC NH

Язык: Английский

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Preliminary exploration of the C-3 galloyl group and the B-5′ hydroxyl group enhance the biological activity of catechins in alleviating obesity induced by high-fat diet in mice

Food Chemistry, Год журнала: 2024, Номер unknown, С. 141785 - 141785

Опубликована: Окт. 1, 2024

Язык: Английский

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Cu-ZrO2@GO Scaffold: Visible Spectrum Triggered caffeine degradation and microbial inactivation

Ceramics International, Год журнала: 2024, Номер 50(19), С. 34623 - 34638

Опубликована: Окт. 1, 2024

Язык: Английский

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