Journal of Heterocyclic Chemistry,
Год журнала:
2022,
Номер
60(4), С. 596 - 605
Опубликована: Дек. 9, 2022
Abstract
A
transition‐metal
and
ligand
free
base‐mediated
a
radical
condensation
reaction
to
form
N
‐substituted
pyrrolyl
ketones
with
water
as
the
side
product
is
developed.
The
transformation
performed
t
‐BuOK,
broad
range
of
acetylpyrroles
alcohols
are
well
tolerated
under
optimized
conditions.
Preliminary
studies
indicate
that
anion
benzylic
alcohol
proposed
key
intermediate,
which
undergoes
coupling
enolate
acetylpyrrole
new
CC
bond.
Subsequently,
corresponding
chalcones
obtained
by
elimination,
enone
intermediate
reduced
afford
ketones.
odor
characteristics
were
evaluated
gas‐chromatography–mass
spectrometry–olfactometry
(GC–MS–O).
present
varied
characteristic
odors,
usually
distinct
from
those
alcohols.
Among
them,
compounds
3‐cyclopropyl‐1‐(1‐methyl‐1H‐pyrrol‐2‐yl)
propan‐1‐one
(3c
′
)
5,9‐dimethyl‐1‐(1‐methyl‐1H‐pyrrol‐2‐yl)
dec‐8‐en‐1‐one
(3g
not
decomposed
high
temperature,
according
results
pyrolysis–GC/MS.
Chemical Reviews,
Год журнала:
2024,
Номер
124(9), С. 6078 - 6144
Опубликована: Апрель 17, 2024
Alcohols
are
abundant
and
attractive
feedstock
molecules
for
organic
synthesis.
Many
methods
their
functionalization
require
them
to
first
be
converted
into
a
more
activated
derivative,
while
recent
years
have
seen
vast
increase
in
the
number
of
complexity-building
transformations
that
directly
harness
unprotected
alcohols.
This
Review
discusses
how
transition
metal
catalysis
can
used
toward
this
goal.
These
broadly
classified
three
categories.
Deoxygenative
functionalizations,
representing
derivatization
C–O
bond,
enable
alcohol
act
as
leaving
group
formation
new
C–C
bonds.
Etherifications,
characterized
by
O–H
represent
classical
reactivity
has
been
modernized
include
mild
reaction
conditions,
diverse
partners,
high
selectivities.
Lastly,
chain
reactions
described,
wherein
acts
mediator
formal
C–H
alkyl
backbone.
Each
these
classes
transformation
will
discussed
context
intermolecular
arylation,
alkylation,
related
reactions,
illustrating
alcohols
harnessed
Inorganic Chemistry,
Год журнала:
2024,
Номер
63(8), С. 3843 - 3849
Опубликована: Фев. 14, 2024
Upgrading
ethanol
to
n-butanol
as
biofuels
is
an
important
topic
for
sustainable
chemistry.
Herein,
a
Cp*Ir
complex
bearing
functional
2,2′-carbonylbibenzimidazole
ligand
[Cp*Ir(2,2′-COBiBzImH2)Cl][Cl]
was
designed
and
synthesized.
In
the
presence
of
catalyst
(0.1
mol
%)
Cs2CO3
(6
%),
highest
yield
updated
up
37%
with
80%
selectivity.
NH
units
in
are
crucially
catalytic
activity
iridium
complex.
Inorganic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 13, 2025
A
water-soluble
iridium
complex
[Cp*Ir(6,6′-(OH)2-2,2′-bpy)(H2O)][OTf]2
was
found
to
be
an
efficient
autotandem
catalyst
for
the
synthesis
of
secondary
alcohols
via
redox
isomerization/atmospheric
hydrogenation
in
water.
The
OH
groups
bpy
ligand
are
a
key
factor
activity
catalyst.
Then,
mechanistic
experiments
and
practical
utilization
catalytic
system
were
presented.
Advanced Synthesis & Catalysis,
Год журнала:
2022,
Номер
364(18), С. 3100 - 3121
Опубликована: Июль 4, 2022
Abstract
The
alkylation
of
ketones
or
secondary
alcohols
using
as
alkylating
agents
via
hydrogen
borrowing
strategy
presents
a
powerful
method
for
the
synthesis
ɑ‐alkylated
ketones.
In
this
review,
we
summarize
progress
catalyzed
by
Ir,
Pd,
Rh,
Ru,
Mn,
Fe,
Co,
Ni,
and
Cu
catalysts
α‐alkylation
with
cross‐coupling
from
2017
to
2021.
A
wide
range
(aromatic
aliphatic
ketones)
(benzylic
primary
alcohols,
aromatic
alkenyl
diols)
are
well
tolerated.
Furthermore,
also
discuss
current
challenges
propose
perspectives
on
coming
development
in
filed.
objective
present
review
is
give
an
overview
recent
advances
β‐alkylation
alcohols.
Finally,
hope
that
will
inspirations
magnified
image
Materials Chemistry Frontiers,
Год журнала:
2022,
Номер
6(9), С. 1228 - 1235
Опубликована: Янв. 1, 2022
A
complex
Ir(tpy)@CTF,
which
is
synthesized
by
the
coordinative
immobilization
of
[Ir(tpy)Cl
3
]
on
a
covalent
triazine
framework,
was
proven
to
be
recycle
catalyst
for
acceptorless
dehydrogenative
coupling
o
-aminobenzyl
alcohols
with
ketones.
