Methanol production and purification via membrane-based technology: Recent advancements, challenges and the way forward

Chemosphere, Год журнала: 2023, Номер 335, С. 139007 - 139007

Опубликована: Май 28, 2023

Язык: Английский

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Unleashing Selective Reduction and Reductive Methylation of N-Heterocycles Using Methanol via Strategic Reaction Condition Modulation

ACS Catalysis, Год журнала: 2025, Номер unknown, С. 3008 - 3022

Опубликована: Фев. 5, 2025

Язык: Английский

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Selective Transfer Hydrogenation of C=O and Conjugated C=C Bonds Using An NHC‐Based Pincer (CNC)Mn^I Complex in Methanol**

ChemSusChem, Год журнала: 2023, Номер 16(18)

Опубликована: Июнь 8, 2023

Base metal catalyzed transfer hydrogenation reactions using methanol is highly challenging. Employing a single N-heterocyclic carbene (NHC)-based pincer (CNC)MnI complex, chemoselective and double of α, β-unsaturated ketones to saturated or alcohols by utilizing as the hydrogen source disclosed. The protocol was tolerant towards selective C=C C=O bonds in presence several other reducible functional groups led synthesis biologically relevant molecules natural products. Notably, this first report Mn-catalyzed carbonyl with methanol. Several control experiments, kinetic studies, Hammett density theory (DFT) calculations were carried out understand mechanistic details catalytic process.

Язык: Английский

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Utilization of methanol for condensation interrupted chemoselective transfer hydrogenation of CC, CO, and CN bonds under low catalyst loading

Organic Chemistry Frontiers, Год журнала: 2023, Номер 10(9), С. 2274 - 2286

Опубликована: Янв. 1, 2023

Selective transfer hydrogenation (TH) of unsaturated molecules using methanol is challenging as the in situ generated formaldehyde prone to react with active methylene ( C -methylation) or amine N core desired product.

Язык: Английский

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B(C6f5)3-Catalyzed Metal-Free Selective Reduction of Α,Β-Unsaturated Ketones with Pinacolborane

Опубликована: Янв. 1, 2025

Язык: Английский

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A well-defined phosphine free metal-ligand cooperative route for N-alkylation of aromatic amines via activation of renewable alcohols catalyzed by a NNN pincer cobalt(II) complexes

Dalton Transactions, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Two cobalt( ii ) complexes C1 and C2, supported by an NNN pincer, were synthesized, characterized with various techniques. These utilized to study catalytic activity in the N -alkylation of amines via borrowing hydrogen strategy.

Язык: Английский

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Transition Metal‐Catalyzed Transformations of Chalcones

The Chemical Record, Год журнала: 2024, Номер 24(8)

Опубликована: Июль 15, 2024

Chalcones are a class of naturally occurring flavonoid compounds associated to variety biological and pharmacological properties. Several reviews have been published describing the synthesis properties vast array analogues. However, overviews on reactivity chalcones has only explored in few accounts. To fill this gap, systematic survey most recent developments transition metal-catalyzed transformation was performed. The chemistry copper, palladium, zinc, iron, manganese, nickel, ruthenium, cobalt, rhodium, iridium, silver, indium, gold, titanium, platinum, among others, as versatile catalysts will be highlighted, covering literature from year 2000 2023, more than 380 publications.

Язык: Английский

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(NNC)Ru(II) Complex Catalyzed Selective Functionalization of Ketones with Methanol: Understanding the Role of Ancillary Ligands

ACS Catalysis, Год журнала: 2023, Номер 13(11), С. 7637 - 7649

Опубликована: Май 23, 2023

Employing a single catalyst and substrate, the selective synthesis of all probable products upon varying reaction conditions is uniquely challenging exciting to explore. Utilizing methanol, cyclometalated (NNC)Ru(II) complex catalyzed transformation wide variety ketones corresponding alcohols, β-methylated α-methylated disclosed. Notably, by changing parameters, for reactions with methanol was achieved. For these transformations, role different ancillary ligands (DMSO, CH3CN PPh3) coordinated Ru(II) center investigated. This protocol successfully applied functionalization few pharmaceutically important molecules sterically hindered α, α′-disubstituted α′, α′′-trisubstituted ketones. Several control experiments, kinetic studies, Hammett DFT calculations were carried out understand this catalytic process.

Язык: Английский

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Methyl Formate, an Alternative Transfer Hydrogenating Agent for Chemoselective Reduction of N-Heteroarenes and Azoarenes

Organic Letters, Год журнала: 2024, Номер 26(21), С. 4486 - 4491

Опубликована: Май 21, 2024

The search for efficient molecular hydrogen precursors and their catalytic exploration is necessary the evolution of transfer hydrogenation. Methyl formate (MF) having high content still remains unexplored such transformations. Herein, we disclosed a bifunctional Ir(III)-complex catalyzed chemoselective TH protocol N-heteroarenes azoarenes using MF. A variety substrates including ten bioactive molecules have been synthesized under mild reaction conditions. probable mechanistic pathway was proposed based on control experiments studies.

Язык: Английский

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Methanol for Hydrogenation and Methylation of Carbonyls: Advances and Challenges in Homogeneous Catalysis

Synlett, Год журнала: 2024, Номер 35(20), С. 2346 - 2366

Опубликована: Окт. 18, 2024

Abstract The catalytic dehydrogenation of methanol to give formaldehyde or formic acid, followed transfer hydrogenation and/or tandem (de)hydrogenation for the and C-methylation carbonyls, offers advantages over traditional methods, including milder reaction conditions, improved safety, greater selectivity, enhanced sustainability. This account provides a comprehensive overview homogeneous catalysts reported various substrates, ketones, chalcones, esters, amides, using as both hydrogen donor methylation source. We provide specific examples mechanistic insights each strategy, offering thorough concise recent advancements from 2014 2024. 1 Introduction 2 Methanol Activation Strategies 3 Hydrogenation Carbonyls 4 Methylation 5 Outlook Summary

Язык: Английский

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