Inorganic nanoparticle-based treatment approaches for colorectal cancer: recent advancements and challenges

Journal of Nanobiotechnology, Год журнала: 2024, Номер 22(1)

Опубликована: Июль 19, 2024

Abstract Colorectal cancer, the third most prevalent cancer globally, contributes significantly to mortality rates, with over 1.9 million reported cases and nearly 935,000 fatalities annually. Surgical resection is a primary approach for localized colorectal tumors, adjunct therapies like chemotherapy, radiotherapy, targeted/immunotherapy considered depending on tumor stage. However, despite preferences targeted immunotherapy post-surgery, chemotherapy remains commonly chosen due its lower cost high cancer-killing efficiency. Yet, faces issues such as resistance severe side effects. Nanotechnology has emerged in therapy by alleviating drawbacks of current treatment approaches. In past few decades, inorganic nanoparticles have shown promise combating offering advantages conventional chemotherapy. Compared organic nanoparticles, exhibit properties photosensitivity, conductivity, magnetic allure, thermal proficiency, allowing them function both drug carriers therapeutic agents. Derived primarily from carbon, silica, metals, metal oxides, they offer superior drug-loading capacity, heightened quantum yield, participation advanced photothermal photodynamic therapies. This review provides brief overview pathophysiology pivotal role therapy, delivery. Additionally, it discusses numerous based recent literature. Graphical abstract

Язык: Английский

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Construction of efficient SrMnO3@rGO nanohybrid as an electrode material for improved electrocapacitive performance

Journal of Energy Storage, Год журнала: 2024, Номер 97, С. 112901 - 112901

Опубликована: Июль 20, 2024

Язык: Английский

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Green synthesis of manganese ferrite magnetic nanoparticle and its modification with metallic-organic frameworks for the tetracycline adsorption from aqueous solutions: A mathematical study of kinetics, isotherms, and thermodynamics

Environmental Research, Год журнала: 2024, Номер 256, С. 118957 - 118957

Опубликована: Апрель 16, 2024

Язык: Английский

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Comparative analysis of vision transformers and convolutional neural networks in osteoporosis detection from X-ray images

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Авг. 3, 2024

Within the scope of this investigation, we carried out experiments to investigate potential Vision Transformer (ViT) in field medical image analysis. The diagnosis osteoporosis through inspection X-ray radio-images is a substantial classification problem that were able address with assistance models. In order provide basis for comparison, conducted parallel analysis which sought solve same by employing traditional convolutional neural networks (CNNs), are well-known and commonly used techniques solution categorization issues. findings our research led us conclude ViT capable achieving superior outcomes compared CNN. Furthermore, provided methods have access sufficient quantity training data, probability increases both arrive at more appropriate solutions critical

Язык: Английский

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Surface properties enhancements by optimizing synthesizing parameters of AA8026 + Zr2O3/TiO2 hybrid composite

Journal of King Saud University - Science, Год журнала: 2024, Номер 36(7), С. 103266 - 103266

Опубликована: Май 24, 2024

Aluminium alloy is one of the widely used lightweight materials and utilized in production a wide variety components. The AA8026 properties enhancements through optimizing synthesizing parameters Taguchi route aim this investigation. Thereby establishing control over stir casting process to alter wear microhardness aluminium by hybrid reinforcement. There were 16 samples + Zr2O3/TiO2 composite prepared as per L16 orthogonal array. varied four levels such stirring time from 15 min 30 min, quantity reinforcement 3 wt% 12 wt%, molten temperature 750 °C 900 °C, speed 450 rpm 600 rpm. fabricated are investigated for properties. From analysis, it inferred that highly influenced results exemplify 0.086 mm3/m was minimum 180.2 HV maximum achieved.

Язык: Английский

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Fabrication of NbTe2@rGO nanosheet by hydrothermal route for cost-effective supercapacitor electrode

Journal of Physics and Chemistry of Solids, Год журнала: 2024, Номер 196, С. 112354 - 112354

Опубликована: Сен. 23, 2024

Язык: Английский

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Adsorption of Rhodamine B dye from solution using 3-((1-(4-((1H-benzo[d]imidazol-2-yl)amino)phenyl)ethylidene)amino)phenol (BIAPEHB)/ P(AA-co-AM) composite

Desalination and Water Treatment, Год журнала: 2025, Номер unknown, С. 101019 - 101019

Опубликована: Янв. 1, 2025

Язык: Английский

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Research Progress of Nanomedicine-Based Mild Photothermal Therapy in Tumor

International Journal of Nanomedicine, Год журнала: 2023, Номер Volume 18, С. 1433 - 1468

Опубликована: Март 1, 2023

Abstract: With the booming development of nanomedicine, mild photothermal therapy (mPTT, 42– 45°C) has exhibited promising potential in tumor therapy. Compared with traditional PTT (> 50°C), mPTT less side effects and better biological conducive to treatment, such as loosening dense structure tissues, enhancing blood perfusion, improving immunosuppressive microenvironment. However, a relatively low temperature cannot allow completely eradicate tumors, therefore, substantial efforts have been conducted optimize application This review extensively summarizes latest advances mPTT, including two sections: (1) taking leading role maximize its effect by blocking cell defense mechanisms, (2) regarding supporting assist other therapies achieve synergistic antitumor curative effect. Meanwhile, special characteristics imaging capabilities nanoplatforms applied various are discussed. At last, this paper puts forward bottlenecks challenges current research path possible solutions directions future proposed correspondingly. Keywords: nanotechnology, therapy,

Язык: Английский

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Recent advances in sonodynamic therapy by MOFs-based platforms for biomedical applications

Dyes and Pigments, Год журнала: 2023, Номер 219, С. 111596 - 111596

Опубликована: Авг. 1, 2023

Язык: Английский

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Recent advances in nanoscale metal–organic frameworks for cancer chemodynamic therapy

Nanoscale, Год журнала: 2023, Номер 15(20), С. 8948 - 8971

Опубликована: Янв. 1, 2023

Recent advances in nanoscale metal organic frameworks for cancer chemodynamic therapy.

Язык: Английский

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