Progress in Materials Science, Год журнала: 2023, Номер 140, С. 101209 - 101209
Опубликована: Ноя. 3, 2023
Язык: Английский
Small, Год журнала: 2021, Номер 17(12)
Опубликована: Фев. 12, 2021
Abstract Nanotechnology has provided great opportunities for managing neoplastic conditions at various levels, from preventive and diagnostic to therapeutic fields. However, when it comes clinical application, nanoparticles (NPs) have some limitations in terms of biological stability, poor targeting, rapid clearance the body. Therefore, biomimetic approaches, utilizing immune cell membranes, are proposed solve these issues. For example, macrophage or neutrophil membrane coated NPs developed with ability interact tumor tissue suppress cancer progression metastasis. The functionality particles largely depends on surface proteins cells their preserved function during extraction coating process NPs. Proteins outer can render a wide range activities NPs, including prolonged blood circulation, remarkable competency recognizing antigens enhanced better cellular interactions, gradual drug release, reduced toxicity vivo. In this review, nano‐based systems cells‐derived membranous layers, detailed production process, applicability treatment discussed. addition, future perspectives challenges translation also presented.
Язык: Английский
Процитировано
370
Molecules, Год журнала: 2023, Номер 28(18), С. 6624 - 6624
Опубликована: Сен. 14, 2023
Knowing the beneficial aspects of nanomedicine, scientists are trying to harness applications nanotechnology in diagnosis, treatment, and prevention diseases. There also potential uses designing medical tools processes for new generation scientists. The main objective conducting this research review is gather widespread nanomedicine under one heading highlight standard practices field. Comprehensive has been conducted incorporate latest data related medicine therapeutics derived from acknowledged scientific platforms. Nanotechnology used conduct sensitive procedures. showing successful fields diagnostics, disease regenerative medicine, gene therapy, dentistry, oncology, aesthetics industry, drug delivery, therapeutics. A thorough association cooperation between physicians, clinicians, researchers, technologies will bring forward a future where there more calculated, outlined, technically programed field nanomedicine. Advances being made overcome challenges associated with application due pathophysiological basis This highlights multipronged how proving health industry. need minimize health, environmental, ethical concerns linked nanotechnology.
Язык: Английский
Процитировано
242
Bioactive Materials, Год журнала: 2024, Номер 37, С. 206 - 221
Опубликована: Март 21, 2024
With the development of nanomedicine, nanomaterials have been widely used, offering specific drug delivery to target sites, minimal side effects, and significant therapeutic effects. The kidneys filtration reabsorption functions, with various potential cell types a complex structural environment, making strategies for kidney function protection recovery after injury complex. This also lays foundation application nanomedicine in diseases. Currently, evidence preclinical clinical settings supports feasibility targeted therapy diseases using based on nanomaterials. prerequisite treating is use carriers good biocompatibility, including nanoparticles, hydrogels, liposomes, micelles, dendrimer polymers, adenoviruses, lysozymes, elastin-like polypeptides. These precise renal uptake, longer half-life, organ distribution, protecting improving efficacy drugs they carry. Additionally, attention should be paid toxicity solubility carriers. While mentioned above used studies both vivo vitro, extensive trials are still needed ensure short-term long-term effects nano human body. review will discuss advantages limitations nanoscale carrier materials diseases, provide more comprehensive catalog nanocarrier materials, offer prospects their drug-loading applications.
Язык: Английский
Процитировано
39
Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(27), С. 6532 - 6549
Опубликована: Янв. 1, 2024
Renal fibrosis is the result of all chronic kidney diseases and becoming a major global health hazard.
Язык: Английский
Процитировано
38
Journal of Agricultural and Food Chemistry, Год журнала: 2024, Номер 72(20), С. 11706 - 11715
Опубликована: Май 10, 2024
In this study, we devised a photothermally stable phytochemical dye by leveraging alizarin in conjunction with the metal-organic framework ZIF-8 (AL@ZIF-8). The approach involved grafting into microporous structure of through physical adsorption and hydrogen-bonding interactions. AL@ZIF-8 significantly enhanced photostability thermostability alizarin. nanoparticles demonstrate substantial color changes various pH environments, showcasing their potential for meat freshness monitoring. Furthermore, introduced an intelligent film utilizing poly(vinyl alcohol)-sodium alginate-AL@ZIF-8 (PA-SA-ZA) detecting beef freshness. sensor exhibited superior water contact angle (52.34°) compared to indicator. stability was under visible UV light (Δ
Язык: Английский
Процитировано
24
Angewandte Chemie International Edition, Год журнала: 2021, Номер 60(29), С. 15809 - 15815
Опубликована: Апрель 20, 2021
Kidney disease is usually "silent" at the early stage but can lead to severe kidney failure later on. The development of bioimaging probes with rapid distribution and long-term retention in significant for precise diagnosis renal diseases. Here, a strategy peptide-mediated delivery accumulation (>48 h) second near-infrared window (NIR-II) fluorophores into demonstrated. It shown that both hepatic-cleared organic molecules fast renal-cleared ultrasmall nanoparticles be retained after conjugation peptide high polarity. Moreover, ROS-responsive activatable bilateral NIR-II sensor was designed based on targeting peptide, which enables vivo monitoring vitro urine analysis. capability peptide-based detect injury report dysfunctional progression particularly crucial chemotherapy regimen optimization timely renoprotective intervention during medication.
Язык: Английский
Процитировано
96
Journal of Controlled Release, Год журнала: 2020, Номер 328, С. 514 - 531
Опубликована: Сен. 18, 2020
Язык: Английский
Процитировано
79
Journal of Controlled Release, Год журнала: 2021, Номер 334, С. 275 - 289
Опубликована: Апрель 27, 2021
Язык: Английский
Процитировано
79
Bioactive Materials, Год журнала: 2020, Номер 5(3), С. 732 - 743
Опубликована: Июнь 15, 2020
Chronic kidney disease (CKD) poses a great burden to global public health as current therapies are generally ineffective. Early detection and effective therapy crucial for the future prevention progression of CKD. Nanoparticles (NPs) vary by particle size, charge, shape density targeting ligands associated with enhancement pharmacokinetic properties, targetability, or bioavailability drugs. Thus, emergence NPs in medicine has provided novel solutions potential diagnosis treatment This review describes experimental research, clinical applications NPs, challenges, upcoming opportunities
Язык: Английский
Процитировано
75
Journal of Controlled Release, Год журнала: 2021, Номер 332, С. 460 - 492
Опубликована: Март 5, 2021
Язык: Английский
Процитировано
75