Biomaterials Advances, Год журнала: 2022, Номер 136, С. 212799 - 212799
Опубликована: Апрель 11, 2022
Язык: Английский
Gels, Год журнала: 2024, Номер 10(5), С. 295 - 295
Опубликована: Апрель 25, 2024
Biomedicine is constantly evolving to ensure a significant and positive impact on healthcare, which has resulted in innovative distinct requisites such as hydrogels. Chitosan-based formulations stand out for their versatile utilization drug encapsulation, transport, controlled release, complemented by biocompatibility, biodegradability, non-immunogenic nature. Stimuli-responsive hydrogels, also known smart have strictly regulated release patterns since they respond adapt based various external stimuli. Moreover, can imitate the intrinsic tissues’ mechanical, biological, physicochemical properties. These characteristics allow stimuli-responsive hydrogels provide cutting-edge, effective, safe treatment. Constant progress field necessitates an up-to-date summary of current trends breakthroughs biomedical application chitosan-based was aim this review. General data about sensitive ions, pH, redox potential, light, electric field, temperature, magnetic are recapitulated. Additionally, responsive multiple stimuli mentioned. Focusing multifaceted thoroughly described. The vast spectrum encompasses neurological disorders, tumors, wound healing, dermal infections. Available chitosan strongly support idea that approaches developing novel solutions worth improving. present paper constitutes valuable resource researchers practitioners currently field.
Язык: Английский
Процитировано
10
Journal of Biomaterials Science Polymer Edition, Год журнала: 2024, Номер 35(15), С. 2402 - 2445
Опубликована: Июль 17, 2024
Protein-based wound dressings have garnered increasing interest in recent years owing to their distinct physical, chemical, and biological characteristics. The intricate molecular composition of proteins gives rise unique characteristics, such as exceptional biocompatibility, biodegradability, responsiveness, which contribute the promotion healing. Wound healing is an ongoing process influenced by multiple causes, it consists four phases. Various treatments been developed repair different types skin wounds, thanks advancements medical technology recognition diverse nature wounds. This review has literature reviewed within last 3-5 years-the progress development protein fundamental properties ideal dressing. Herein, strides protein-based state-of-the-art dressing emphasize significant challenges summarize future perspectives for applications.
Язык: Английский
Процитировано
10
Small, Год журнала: 2024, Номер 21(1)
Опубликована: Окт. 23, 2024
Abstract Over the past decade, precision medicine has garnered increasing attention, making significant strides in discovering new therapeutic drugs and mechanisms, resulting notable achievements symptom alleviation, pain reduction, extended survival rates. However, limited target specificity of primary inter‐individual differences have often necessitated high‐dosage strategies, leading to challenges such as restricted deep tissue penetration rates systemic side effects. Material science advancements present a promising avenue for these issues. By leveraging distinct internal features diseased regions application specific external stimuli, responsive materials can be tailored achieve targeted delivery, controllable release, biochemical reactions. This review aims highlight latest stimuli‐responsive their potential medicine. Initially, we introduce disease‐related stimuli capable elucidating reaction principles functional groups. Subsequently, provide detailed analysis representative pre‐clinical across various clinical applications, including enhancements treatment cancers, injury diseases, inflammatory infection high‐throughput microfluidic biosensors. Finally, discuss some challenges, off‐target effects, long‐term impacts nano‐materials, ethical concerns, offer insights into future perspectives materials.
Язык: Английский
Процитировано
10
Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 160620 - 160620
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
1
Biomaterials Advances, Год журнала: 2022, Номер 136, С. 212799 - 212799
Опубликована: Апрель 11, 2022
Язык: Английский
Процитировано
33