Advances in smart mesoporous carbon nanoplatforms for photothermal–enhanced synergistic cancer therapy

Chemical Engineering Journal, Год журнала: 2022, Номер 435, С. 134886 - 134886

Опубликована: Янв. 29, 2022

Язык: Английский

---

Multifunctional mesoporous silica nanoparticles for biomedical applications

Signal Transduction and Targeted Therapy, Год журнала: 2023, Номер 8(1)

Опубликована: Ноя. 24, 2023

Abstract Mesoporous silica nanoparticles (MSNs) are recognized as a prime example of nanotechnology applied in the biomedical field, due to their easily tunable structure and composition, diverse surface functionalization properties, excellent biocompatibility. Over past two decades, researchers have developed wide variety MSNs-based nanoplatforms through careful design controlled preparation techniques, demonstrating adaptability various application scenarios. With continuous breakthroughs MSNs fields biosensing, disease diagnosis treatment, tissue engineering, etc., gradually moving from basic research clinical trials. In this review, we provide detailed summary beginning with comprehensive overview development history. We then discuss types nanostructured architectures, well classification nanocomposites according elements existed inorganic functional components. Subsequently, summarize primary purposes surface-functionalized modifications MSNs. following, applications MSNs, highlight targeted therapeutic modalities currently developed. Given importance translation, also progress Finally, take perspective on future direction remaining challenges field.

Язык: Английский

---

Recent advances in multi-configurable nanomaterials for improved chemodynamic therapy

Coordination Chemistry Reviews, Год журнала: 2022, Номер 474, С. 214861 - 214861

Опубликована: Окт. 1, 2022

Язык: Английский

---

Current advances in metal–organic frameworks for cancer nanodynamic therapies

Coordination Chemistry Reviews, Год журнала: 2023, Номер 497, С. 215434 - 215434

Опубликована: Сен. 17, 2023

Язык: Английский

---

Chitosan- and hyaluronic acid-based nanoarchitectures in phototherapy: Combination cancer chemotherapy, immunotherapy and gene therapy

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 273, С. 132579 - 132579

Опубликована: Май 23, 2024

Язык: Английский

---

Pore engineering of micro/mesoporous nanomaterials for encapsulation, controlled release and variegated applications of essential oils

Journal of Controlled Release, Год журнала: 2024, Номер 367, С. 107 - 134

Опубликована: Янв. 25, 2024

Язык: Английский

---

Nanoparticles-based phototherapy systems for cancer treatment: Current status and clinical potential

Bioactive Materials, Год журнала: 2022, Номер 23, С. 471 - 507

Опубликована: Дек. 5, 2022

Remarkable progress in phototherapy has been made recent decades, due to its non-invasiveness and instant therapeutic efficacy. In addition, with the rapid development of nanoscience nanotechnology, systems based on nanoparticles or nanocomposites also evolved as an emerging hotspot nanomedicine research, especially cancer. this review, first we briefly introduce history phototherapy, mechanisms cancer treatment. Then, summarize representative over past three five years nanoparticle-based highlight design innovative thereof. Finally, discuss feasibility potential clinical anticancer applications, aiming predict future research directions field. Our review is a tutorial work, at providing useful insights researchers field

Язык: Английский

---

Biomimetic smart mesoporous carbon nanozyme as a dual-GSH depletion agent and O2 generator for enhanced photodynamic therapy

Acta Biomaterialia, Год журнала: 2022, Номер 148, С. 310 - 322

Опубликована: Июнь 5, 2022

Язык: Английский

---

Optimized strategies of ROS-based nanodynamic therapies for tumor theranostics

Biomaterials, Год журнала: 2023, Номер 303, С. 122391 - 122391

Опубликована: Ноя. 15, 2023

Язык: Английский

---

Nanoparticle-mediated synergistic anticancer effect of ferroptosis and photodynamic therapy: novel insights and perspectives

Asian Journal of Pharmaceutical Sciences, Год журнала: 2023, Номер 18(4), С. 100829 - 100829

Опубликована: Июль 1, 2023

Current antitumor monotherapy has many limitations, highlighting the need for novel synergistic anticancer strategies. Ferroptosis is an iron-dependent form of nonapoptotic cell death that plays a pivotal regulatory role in tumorigenesis and treatment. Photodynamic therapy (PDT) causes irreversible chemical damage to target lesions widely used therapy. However, PDT's effectiveness usually hindered by several obstacles, such as hypoxia, excess glutathione (GSH), tumor resistance. improves efficacy PDT increasing oxygen reactive species (ROS) or reducing GSH levels, also enhances ferroptosis induction due ROS effect microenvironment (TME). Strategies based on nanoparticles (NPs) can subtly exploit potential synergy PDT. This review explores recent advances current challenges landscape underlying mechanisms regulating PDT, well nano delivery system-mediated activity. These include polymers, biomimetic materials, metal organic frameworks (MOFs), inorganics, carrier-free NPs. Finally, we highlight future perspectives this emerging paradigm targeted cancer therapies.

Язык: Английский

---