Nano-encapsulation of drugs to target hepatic stellate cells: Toward precision treatments of liver fibrosis DOI
Yue Yuan, Jiaxuan Li, Min Chen

и другие.

Journal of Controlled Release, Год журнала: 2024, Номер 376, С. 318 - 336

Опубликована: Окт. 18, 2024

Язык: Английский

Engineered liposomes targeting hepatic stellate cells overcome pathological barriers and reverse liver fibrosis DOI
Kaili Wang, Hao Chen,

Jiani Zheng

и другие.

Journal of Controlled Release, Год журнала: 2024, Номер 368, С. 219 - 232

Опубликована: Фев. 28, 2024

Язык: Английский

Процитировано

16
The evidence-based multifaceted roles of hepatic stellate cells in liver diseases: A concise review DOI
Jong‐Won Kim,

Yu Ji Kim

Life Sciences, Год журнала: 2024, Номер 344, С. 122547 - 122547

Опубликована: Март 7, 2024

Язык: Английский

Процитировано

10
Abnormal metabolism in hepatic stellate cells: Pandora's box of MAFLD related hepatocellular carcinoma DOI

Yuan-dong Sun,

Hao Zhang, Yuanmin Li

и другие.

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, Год журнала: 2024, Номер 1879(2), С. 189086 - 189086

Опубликована: Фев. 9, 2024

Язык: Английский

Процитировано

7
The impact of, and expectations for, lipid nanoparticle technology: From cellular targeting to organelle targeting DOI
Yusuke Sato, Takashi Nakamura, Yuma Yamada

и другие.

Journal of Controlled Release, Год журнала: 2024, Номер 370, С. 516 - 527

Опубликована: Май 9, 2024

Язык: Английский

Процитировано

6
Nanoparticle: Pathogenesis, Innovative Diagnosis, and Therapy of Liver Fibrosis DOI
Wen Lin, X Liu,

Dejun Yang

и другие.

ChemistrySelect, Год журнала: 2025, Номер 10(7)

Опубликована: Фев. 1, 2025

Abstract Liver fibrosis, a progressive condition resulting from chronic liver injury, can lead to cirrhosis and hepatocellular carcinoma. Nanoparticles have emerged as promising tools for their diagnosis treatment due unique properties. This review highlights advances in lipid‐based (e.g., liposomes, solid lipid nanoparticles), polymer‐based nanocapsules, dendrimers), inorganic iron oxide, gold biological nanoparticles extracellular vesicles, exosomes). These enhance imaging contrast MRI CT, enabling non‐invasive fibrosis detection, deliver drugs or gene‐editing hepatic stellate cells (HSCs) targeted therapy. Extracellular vesicles (EVs) exosomes also show potential biomarkers therapeutic carriers. However, challenges such limited targeting efficiency, toxicity, difficulties clinical translation remain. Future research should focus on optimizing nanoparticle design, improving biocompatibility, addressing regulatory issues facilitate application. Nanoparticle‐based strategies hold great promise revolutionizing management.

Язык: Английский

Процитировано

0
Molecular mechanisms of lncRNA NEAT1 in the pathogenesis of liver-related diseases, with special focus on therapeutic approaches DOI

Ya‐Hui Wang,

Gaurav Sanghvi, Suhas Ballal

и другие.

Pathology - Research and Practice, Год журнала: 2025, Номер 269, С. 155867 - 155867

Опубликована: Фев. 26, 2025

Язык: Английский

Процитировано

0
Harnessing the composition of lipid nanoparticles to selectively deliver mRNA to splenic immune cells for anticancer vaccination DOI
Mahmoud A. Younis, Yusuke Sato, Yaser Hosny Ali Elewa

и другие.

Drug Delivery and Translational Research, Год журнала: 2025, Номер unknown

Опубликована: Март 7, 2025

Язык: Английский

Процитировано

0
MCT4 Knockdown by Tumor Microenvironment-Responsive Nanoparticles Remodels the Cytokine Profile and Eradicates Aggressive Breast Cancer Cells DOI
Ahmed A. H. Abdellatif, Abdellatif Bouazzaoui, Hesham M. Tawfeek

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 238, С. 113930 - 113930

Опубликована: Апрель 25, 2024

Язык: Английский

Процитировано

3
Hepatic stellate cell-targeted chemo-gene therapy for liver fibrosis using fluorinated peptide-lipid hybrid nanoparticles DOI

Qiuyue Lai,

Wenlong Li,

Dandan Hu

и другие.

Journal of Controlled Release, Год журнала: 2024, Номер 376, С. 601 - 617

Опубликована: Окт. 25, 2024

Язык: Английский

Процитировано

3
Targeted Nanoparticles: the Smart Way for the Treatment of Colorectal Cancer DOI
Ahmed A. H. Abdellatif,

Abdulmajeed S. Alshubrumi,

Mahmoud A. Younis

и другие.

AAPS PharmSciTech, Год журнала: 2024, Номер 25(1)

Опубликована: Янв. 24, 2024

Язык: Английский

Процитировано

2