The invisible Threat: Assessing the reproductive and transgenerational impacts of micro- and nanoplastics on fish

Environment International, Год журнала: 2024, Номер 183, С. 108432 - 108432

Опубликована: Янв. 1, 2024

Micro- and nanoplastics (MNPs), emerging as pervasive environmental pollutants, present multifaceted threats to diverse ecosystems. This review critically examines the ability of MNPs traverse biological barriers in fish, leading their accumulation gonadal tissues subsequent reproductive toxicity. A focal concern is potential transgenerational harm, where offspring not directly exposed exhibit toxic effects. Characterized by extensive specific surface areas marked hydrophobicity, readily adsorb concentrate other contaminants, potentially intensifying comprehensive analysis aims provide profound insights into repercussions on fish health progeny, highlighting intricate interplay between pollutants. We delve mechanisms MNPs-induced toxicity, including histopathologic alterations, oxidative stress, disruptions hypothalamic-pituitary-gonadal axis. The also underscores urgency for future research explore size-specific dynamics long-term implications chronic exposure. Understanding these aspects crucial assessing ecological risks posed formulating strategies safeguard aquatic life.

Язык: Английский

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Microplastics contamination in food products: Occurrence, analytical techniques and potential impacts on human health

Current Research in Biotechnology, Год журнала: 2024, Номер 7, С. 100190 - 100190

Опубликована: Янв. 1, 2024

Chemically, microplastics (MPs) are synthetic materials composed of plastic monomers and additives vary in size from 0.1 to 5000 μm. Due their chemical stability the widespread use plastics for various purposes, MP contamination environment has increased dramatically, leading daily consumer products as well. Although previous studies have reported environmental impacts MPs, only a few highlighted occurrence MPs food possible effects on human health. Recent investigations identified particles drinking water other beverages, seafood, plant products, salt, sugar, honey, raising an alarm over safety quality these items. Ingestion, inhalation, dermal contact such goods common routes through which may enter body can several deleterious health including oxidative stress, inflammation, immunotoxicity, risk neoplasia, cellular metabolism impairment, neurotoxicity, gut microbiome dysbiosis, disruption reproductive system among others. A collective approach employing source control, recycling, biodegradable plastics, strengthening legislation, bioremediation could be promising sustainable solution control pollution. The key challenge appears standarize detection methods along with reducing well environment. Therefore, this review focuses current analysis, potential impacts, strategies mitigate It also adds novel findings, knowledge gaps, recommendations that guide future research field.

Язык: Английский

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The hidden threat: Unraveling the impact of microplastics on reproductive health

The Science of The Total Environment, Год журнала: 2024, Номер 935, С. 173177 - 173177

Опубликована: Май 13, 2024

Язык: Английский

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A review of the neurobehavioural, physiological, and reproductive toxicity of microplastics in fishes

Ecotoxicology and Environmental Safety, Год журнала: 2024, Номер 282, С. 116712 - 116712

Опубликована: Июль 15, 2024

Microplastics (MPs) have emerged as widespread environmental pollutants, causing significant threats to aquatic ecosystems and organisms.This review examines the toxic effects of MPs on fishes, with a focus neurobehavioural, physiological, reproductive impacts, well underlying mechanisms toxicity.Evidence indicates that induce range neurobehavioural abnormalities in affecting social interactions cognitive functions.Altered neurotransmitter levels are identified key mechanism driving behavioural alterations following MP exposure.Physiological fishes exposed also reported, including neurotoxicity, immunotoxicity, oxidative stress.These physiological disruptions can compromise individual health organisms.Furthermore, linked exposure discussed, particular emphasis endocrine signaling pathways.These impair success fish species, impacting population numbers.Here we explore critical role mediating after MPs, focusing primarily hypothalamic-pituitary-gonadal axis.Our highlights urgent need for interdisciplinary research efforts aimed at elucidating full extent toxicity its implications ecosystems.Lastly, identify knowledge gaps future research, investigations into transgenerational if any, quantifying synergetic/antagonistic other pollutants.This expanded regarding potential risks wildlife is expected aid policymakers developing mitigation strategies protect species.

Язык: Английский

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The micro(nano)plastics perspective: exploring cancer development and therapy

Molecular Cancer, Год журнала: 2025, Номер 24(1)

Опубликована: Янв. 24, 2025

Microplastics, as an emerging environmental pollutant, have received widespread attention for their potential impact on ecosystems and human health. Microplastics are defined plastic particles less than 5 millimeters in diameter can be categorized primary secondary microplastics. Primary microplastics usually originate directly from industrial production, while formed by the degradation of larger items. capable triggering cytotoxicity chronic inflammation, may promote cancer through mechanisms such pro-inflammatory responses, oxidative stress endocrine disruption. In addition, improved bring new perspectives to therapy, studies drug carriers underway, showing high targeting bioavailability. Although current suggest association between certain cancers (e.g., lung, liver, breast cancers), long-term effects specific still need studied. This review aimed at exploring carcinogenicity promising applications therapy provides important directions future research emphasizes multidisciplinary collaboration address this global health challenge.

Язык: Английский

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Microplastics in Food Products: Prevalence, Artificial Intelligence Based Detection, and Potential Health Impacts on Humans

Emerging contaminants, Год журнала: 2025, Номер unknown, С. 100477 - 100477

Опубликована: Янв. 1, 2025

Язык: Английский

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Behavioral Studies of Zebrafish Reveal a New Perspective on the Reproductive Toxicity of Micro- and Nanoplastics

Toxics, Год журнала: 2024, Номер 12(3), С. 178 - 178

Опубликована: Фев. 26, 2024

The escalating prevalence of microplastics and nanoplastics in aquatic environments is a major challenge affecting the behavior reproductive health organisms while posing potential risks to human ecosystems. This review focuses on neurobehavioral changes toxicity MNPs zebrafish their relationships. At same time, caused by were studied, synergistic effects interaction these pollutants with other environmental contaminants explored. In addition, zebrafish, as model organism, provide valuable insights into subtle but important behavior, which critical for understanding success, suggesting that behavioral can serve an early biomarker toxicity. based classical endocrine disruptor models research methods, current status was reviewed, further indicated parameters be used effective rapid tool evaluate MNPs. However, methods rapidly assessing are still area exploration. To address limitations challenges scope research, this outlines future directions aim improving our impacts work aims inform targeted policies advance public strategies growing pollution.

Язык: Английский

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Meta-analysis of the Effects of Microplastic on Fish: Insights into Growth, Survival, Reproduction, Oxidative Stress, and Gut Microbiota Diversity

Water Research, Год журнала: 2024, Номер 267, С. 122493 - 122493

Опубликована: Сен. 21, 2024

Язык: Английский

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Polystyrene microplastics induced disturbances in neuronal arborization and dendritic spine density in mice prefrontal cortex

Chemosphere, Год журнала: 2024, Номер 351, С. 141165 - 141165

Опубликована: Янв. 13, 2024

Язык: Английский

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Microplastics influencing aquatic environment and human health: A review of source, determination, distribution, removal, degradation, management strategy and future perspective

Journal of Environmental Management, Год журнала: 2025, Номер 375, С. 124249 - 124249

Опубликована: Янв. 26, 2025

Язык: Английский

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