Antioxidant and antimicrobial activities of Spirulina platensis extracts and biogenic selenium nanoparticles against selected pathogenic bacteria and fungi

Saudi Journal of Biological Sciences, Год журнала: 2021, Номер 29(2), С. 1197 - 1209

Опубликована: Сен. 17, 2021

This study investigated the antimicrobial and antioxidant activity of three Spirulina extracts (methanol, acetone, hexane) biological selenium nanoparticles (SeNPs) fabricated by Bacillus subtilis AL43. The results showed that exhibited against tested pathogens. Besides, significantly scavenged ABTS DPPH radicals in a dose-dependent manner. methanolic extract had higher total phenolic content, activity, than other extracts. were synthesized AL43 under aerobic conditions characterized as spherical, crystalline with size 65.23 nm net negative charge -22.7. We evidenced SeNPs possess considerable gram-positive, gram-negative bacteria, strains from both Candida sp. Aspergillus Moreover, able to scavenge An association was found between content their activities. Our indicate significant activities seem be successful candidates for safe reliable medical applications.

Язык: Английский

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Functional roles of taurine, L-theanine, L-citrulline, and betaine during heat stress in poultry

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology, Год журнала: 2022, Номер 13(1)

Опубликована: Март 10, 2022

Heat stress (HS) is an important environmental factor affecting poultry production on a global scale. With the rise in ambient temperature and increasing effects of warming, it becomes pertinent to understand HS strategies that can be adopted mitigate its detrimental impacts performance, health, welfare, immunity, survival birds. Amino acids (AAs) have been increasingly as nutritional modifiers animals ameliorate adverse HS. They are essential for protein synthesis, growth, maintenance, reproduction, response, whole-body homeostasis. However, tends adversely affect availability, transport, absorption, utilization these AAs. Studies investigated provision AAs during conditions, variable findings reported. Taurine, L-theanine, L-citrulline non-essential amino gaining attention supplements animals. Similarly, betaine acid derivative possesses favorable biological properties which contributes role functional additive Of particular note, taurine negligible plants, while betaine, found selected plants. These nutrients barely feed ingredients, but their supply has shown elicit physiological roles including anti-stress effects, anti-oxidative, anti-inflammatory, gut promoting, immunomodulatory functions. The present review provides information use nutritionally physiologically beneficial additives diets conditions. Presently, although several studies reported positive human murine studies, however, there limited regarding heat nutrition. Therefore, this aims expound nutrients, potentials alleviation, stimulate further researches

Язык: Английский

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Global trends and research frontiers on heat stress in poultry from 2000 to 2021: A bibliometric analysis

Frontiers in Physiology, Год журнала: 2023, Номер 14

Опубликована: Фев. 7, 2023

Background: Heat stress remains a major environmental factor affecting poultry production. With growing concerns surrounding climate change and its antecedent of global warming, research on heat in has gradually gained increased attention. Therefore, this study aimed to examine the current status, identify frontiers, highlight trends using bibliometric analysis. Methods: The literature search was performed Web Science Core Collection database for documents published from 2000 2021. retrieved were analyzed their publication counts, countries, institutions, keywords, sources, funding, citation records app R software. Network analysis co-authorship, co-occurrence, citation, co-citation, bibliographic coupling visualized VOSviewer Results: A total 468 publications retrieved, over past two decades, there gradual increase annual number (average growth rate: 4.56%). China had highest contribution with respect publications, top contributing authors, collaborations, funding agencies, institutions. Nanjing Agricultural University, most prolific institution. Kazim Sahin Firat Turkey contributed citations research, Poultry productive cited journal. 10 globally mainly focused effects stress, alleviation association between oxidative poultry. All keywords grouped into six clusters which included studies "growth performance", "intestinal morphology", "heat stress", "immune response", "meat quality", "oxidative stress" as hotspots. In addition, topics such as; "antioxidants", "microflora", barrier", "rna-seq", "animal welfare", "gene expression", "probiotics", "feed restriction", "inflammatory pathways" identified future Conclusion: This provides detailed comprehensive last it is expected serve useful reference potential that will help address impacts production globally.

Язык: Английский

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Pre-hatch thermal manipulation of embryos and post-hatch baicalein supplementation mitigated heat stress in broiler chickens

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology, Год журнала: 2024, Номер 15(1)

Опубликована: Янв. 22, 2024

Abstract Background High environmental temperatures induce heat stress in broiler chickens, affecting their health and production performance. Several dietary, managerial, genetics strategies have been tested with some success mitigating (HS) broilers. Developing novel HS mitigation for sustaining is critically needed. This study investigated the effects of pre-hatch thermal manipulation (TM) post-hatch baicalein supplementation on growth performance parameters heat-stressed Results Six hundred fertile Cobb 500 eggs were incubated 21 d. After candling embryonic day (ED) 10, 238 thermally manipulated at 38.5 °C 55% relative humidity (RH) from ED 12 to 18, then transferred hatcher (ED 19 21, standard temperature) 236 a controlled temperature (37.5 °C) till hatch. hatch, 180-day-old chicks both groups raised 36 pens ( n = 10 birds/pen, 6 replicates per treatment). The treatments were: 1) Control, 2) TM, 3) control (CHS), 4) (TMHS), 5) supplement (CHSS), 6) (TMHSS). All birds under environment d, followed by chronic d 22 35 (32–33 8 h) CHS, TMHS, CHSS, TMHSS groups. A thermoneutral (22–24 was maintained Control TM RH constant (50% ± 5%) throughout trial. data analyzed using one-way ANOVA R GraphPad software P < 0.05 are presented as mean SEM. Heat significantly decreased 0.05) final body weight ADG CHS TMHS compared other Embryonic increased expression shock protein-related genes HSP70, HSP90, HSPH1 ) antioxidant-related GPX1 TXN ). showed significant increment total cecal volatile fatty acid (VFA) concentration birds. microbial analysis enrichment alpha beta diversity Coprococcus group. Conclusions Pre-hatch mitigate detrimental chickens' performance, upregulate favorable gene expression, increase VFA production, promote gut increasing beneficial communities.

Язык: Английский

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The impact of dietary supplementation of polysaccharide derived from Polygonatum sibiricum on growth, antioxidant capacity, meat quality, digestive physiology, and gut microbiota in broiler chickens

Poultry Science, Год журнала: 2024, Номер 103(6), С. 103675 - 103675

Опубликована: Март 22, 2024

Polygonatum sibiricum polysaccharide (PSP) has demonstrated diverse medicinal properties, extensively researched for human applications. Nonetheless, there is a lack of studies investigating the potential advantages PSP in poultry farming. The present study investigated impact incorporating into broiler diets on their growth performance, meat quality, blood metabolites, antioxidative status, and ileal histomorphology. Two hundred forty-one-day-old male Ross-308 chicks (44.98 ± 0.79 g) were randomly assigned to 3 experimental groups, with 8 replicates 10 birds each. fed supplemented at 0, 400, 800 mg/kg (control, PSP400, PSP800, respectively). results revealed linear (P > 0.05) improvement body weight gain, European production efficiency index, feed conversion ratio during grower (22-35 d) overall periods (1-35 d). pH levels ingluvies, ileum, cecum exhibited reduction PSP800 group d 21 35, respectively. Villus height crypt depth increased PSP400 groups compared control group. decreased hydrogen peroxide (H

Язык: Английский

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Effects of supplemental vitamin A on reproduction and antioxidative status of aged laying hens, and growth, blood indices and immunity of their offspring

Poultry Science, Год журнала: 2024, Номер 103(3), С. 103453 - 103453

Опубликована: Янв. 11, 2024

The purpose of this investigation was to evaluate the impacts vitamin A (VA) supplementation in feed at levels 0 (control), 2,000, 4,000, 6,000, and 8,000 IU VA/kg diet on reproductive efficiency antioxidative properties aged Sinai laying hens 52 wk age (n = 300 females 30 males) 6 replicates (10 + 1 male/replicate). As well as blood biochemical indicators, carcass characteristics, growth performance, immunity, status their chicks. Results showed that diets supplemented with 2,000 or 6,000 IU/kg VA increased fertility rate decreased early embryonic mortality (P < 0.05). Increasing from 4,000 significantly boosted hatchability rates. All enhanced glutathione peroxidase (GPx) reduced malondialdehyde (MDA) late mortality. In shell gland, dietary actions GPx actions, catalase (CAT), superoxide dismutase (SOD). hatched chicks, all 0.05) hemoglobin, red cell count, serum concentration total proteins IgA while decreasing eosinophils percentage aspartate aminotransferase activity (AST) concentration. Dietary supplementations improved lymphocytes, antioxidant capacity (TAC), SOD, IgM, heterophils, heterophils/lymphocytes ratio, creatinine Serum triglyceride by adding VA, globulin high-density lipoprotein concentrations were heightened only VA. It could be concluded (6,000 IU/kg) liver gland hemato-biochemicals parameters, status, immunity offspring.

Язык: Английский

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Regulation of serum reproductive hormones, gap junction proteins, and cytokine profiles in laying hens fed varying levels of expanded black soldier fly meal

Poultry Science, Год журнала: 2025, Номер 104(5), С. 105045 - 105045

Опубликована: Март 16, 2025

This study examined the impact of expanded black soldier fly (EP-BSF) meal on laying hens' reproductive hormones, gap junction proteins, cytokines, and performance. Over 12 weeks trail period, 400 Hy-Line brown hens procured at 24 age underwent a completely randomized design with 5 treatments, 8 replicates, 10 birds per replicate. The received control diet (CON) or diets 3 %, 6 9 % EP-BSF. Results demonstrated that lower EP-BSF levels showed linearly higher (p < 0.05) hen day egg production (HDEP) from 30 to 33 mass (EM) in cumulative comparable CON. Tendencies towards average weight (AEW) was observed when incorporated CON during 34-37 = 0.079), as well 0.056). Yolk color quadratically 0.024) 30-33 weeks, tendency 0.050) level increases. Albumin supplementation 26-29 0.062) weeks. Eggshell thickness increased increased. Serum estradiol (E2) were groups, correlating expression connexins GJA1 GJA4 oviductal tissues tumor necrosis factor-alpha (TNF-α). In conclusion, incorporation had similar HDEP, AEW, EM, albumin We attributed this E2 resulting TNF-α, GJA chicken oviduct. Our findings also strongly indicate estrogen plays role modulating connexins. These suggest layer may serve an alternative protein source for poultry feed.

Язык: Английский

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Effects of Dietary Supplementation of Algae-Derived Polysaccharides on Morphology, Tight Junctions, Antioxidant Capacity and Immune Response of Duodenum in Broilers under Heat Stress

Animals, Год журнала: 2021, Номер 11(8), С. 2279 - 2279

Опубликована: Авг. 2, 2021

To evaluate the ameliorative effect of algae-derived polysaccharide (ADP) supplementation on duodenal injury caused by heat stress (HS) in broilers, a total 144 male yellow-feathered broilers (56-day-old) were randomly allocated into three groups: The TN group (thermoneutral zone, raised at 23.6 ± 1.8 °C); HS (heat stress, exposed to 33.2 1.5 °C 10 h/day, 8:00 a.m.–18:00 p.m., temperature remaining period was consistent with group); HSA (heat-stressed fed ADP supplemented diet 1000 mg/kg). There six replications each treatment, and eight replication. feeding trial lasted four weeks. results showed that dietary tended increase villus height (p = 0.077) width 0.062), decrease apoptosis rate 0.081) duodenum under HS. Furthermore, increased relative mRNA protein (based immunofluorescence) expression levels occludin zonula occludens-1 (ZO-1) < 0.05). In addition, enhanced antioxidation capacity (T-AOC) activity glutathione-S transferase (GST), while reducing malondialdehyde (MDA) concentration Moreover, upregulated nuclear factor erythroid 2-related 2 (Nrf2), heme oxygenase-1 (HO-1), glutathione peroxidase 1 (GPx1) S-transferase theta (GSTT1) heat-stressed compared group, an had higher inhibitor kappa B alpha (IκBα) 0.05) lower tumor necrosis factor-α (TNF-α) interleukin-1β (IL-1β) summary, HS-induced impairment tight junctions, antioxidant immune response broilers. These beneficial effects might be related modulation Nrf2 NF-κB signaling pathways.

Язык: Английский

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Managing Gut Microbiota through In Ovo Nutrition Influences Early-Life Programming in Broiler Chickens

Animals, Год журнала: 2021, Номер 11(12), С. 3491 - 3491

Опубликована: Дек. 7, 2021

The chicken gut is the habitat to trillions of microorganisms that affect physiological functions and immune status through metabolic activities host interaction. Gut microbiota research previously focused on inflammation; however, it now clear these microbial communities play an essential role in maintaining normal homeostatic conditions by regulating system. In addition, helps reduce prevent pathogen colonization via mechanism competitive exclusion synthesis bactericidal molecules. Under commercial conditions, newly hatched chicks have access feed after 36–72 h hatching due hatch window routine hatchery practices. This delay adversely affects potential inoculation healthy impairs development maturation muscle, system, gastrointestinal tract (GIT). Modulating has been proposed as a strategy for improving health productivity avoiding undesirable effects Using early-life programming ovo stimulation with probiotics prebiotics, may be possible avoid selected disorders, poor immunity, resistance, which broiler industry faces selection pressures imposed increasingly demanding market.

Язык: Английский

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A review of heat stress in chickens. Part II: Insights into protein and energy utilization and feeding

Frontiers in Physiology, Год журнала: 2022, Номер 13

Опубликована: Авг. 8, 2022

With the growing global demand for animal protein and rising temperatures caused by climate change, heat stress (HS) is one of main emerging environmental challenges poultry industry. Commercially-reared birds are particularly sensitive to hot temperatures, so adopting production systems that mitigate adverse effects HS on bird performance essential requires a holistic approach. Feeding nutrition can play important roles in limiting load birds; therefore, this review aims describe feed intake (FI) nutrient digestibility highlight feeding strategies nutritional solutions potentially some deleterious broiler chickens. The reduction FI behavioral changes induced as attempt limit associated with digestion, absorption, metabolism nutrients. Although intensity length period influences type magnitude responses, reduced explains most degradation observed broilers, while appears only explain small proportion impaired efficiency following HS. Targeted strategies, including restriction withdrawal, dual feeding, wet have showed promising results under but these be difficult implement intensive rearing systems. Concerning diet composition, increased energy diets compensate decreased during Indeed, high crude both been shown improve conditions. Specifically, positive may obtained added fat concentrations since lipids lower thermogenic effect compared proteins carbohydrates. Moreover, supplementation amino acids help support acid requirements maintenance functions Further research better characterize advance will establish economically viable enhance productivity, health, welfare, meat quality broilers facing

Язык: Английский

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