Saudi Journal of Biological Sciences,
Год журнала:
2021,
Номер
29(3), С. 1428 - 1433
Опубликована: Ноя. 24, 2021
Diabetes
is
a
worldwide
public
health
disease.
Currently,
the
most
effective
way
to
treat
diabetes
mitigate
postprandial
hyperglycemia
by
inhibiting
carbohydrate
hydrolysis
enzymes
in
digestive
system.
Plant
extracts
are
rich
bioactive
compounds,
which
can
be
used
treatment.
This
study
aims
evaluate
polyphenols
content
ethanolic
of
avocado
fruit
and
leaves
(Persea
americana
Mill.).
Additionally,
their
antioxidant
activity
using
DPPH,
while
inhibition
ability
α-amylase
was
examined
reacting
different
amounts
with
compared
acarbose
as
standard
inhibitor.
The
active
compounds
were
detected
LC/MS.
obtained
results
showed
that
leaf
extract
recorded
significant
total
phenolic
(178.95
145.7
mg
GAE
/g
dry
weight,
respectively).
flavonoid
values
ranged
from
32.5
70.08
QE/g
weight
extracts,
respectively.
Twenty-six
phytogenic
These
belong
fatty
acids,
sterols,
triterpenes,
flavonoids.
due
exist
i.e.,
increased
concentration
dependant
manner.
Avocado
(1000
µg/mL)
scavenged
95%
DPPḢ
rummaged
91.03%
free
radicals
Vit
C
BHT.
higher
inhibitory
observed
than
extract,
where
μg/ml)
inhibited
enzyme
92.13%
88.95%,
could
have
impact
on
human
high
polyphenols.
Poultry Science,
Год журнала:
2021,
Номер
101(2), С. 101584 - 101584
Опубликована: Ноя. 8, 2021
Increasing
market
pressure
to
reduce
the
use
of
antibiotics
and
Veterinary
Feed
Directive
2019
have
led
expanded
research
on
alternate
antibiotic
solutions.
This
review
aimed
assess
benefits
using
essential
oils
(EOs)
their
nanoemulsions
(NEs)
as
feed
supplements
for
poultry
potential
alternatives
in
organic
production.
Antibiotics
are
commonly
used
enhance
growth
prevent
diseases
animals
due
antimicrobial
activities.
EOs
a
complex
mixture
volatile
compounds
derived
from
plants
manufactured
via
various
fermentation,
extraction,
steam
distillation
methods.
categorized
into
2
groups
compounds:
terpenes
phenylpropenes.
Differences
among
depend
source
plant
type,
physical
chemical
soil
conditions,
harvest
time,
maturity,
drying
technology
used,
storage
extraction
time.
can
be
therapeutic
purposes
situations
broiler
production
they
possess
antibacterial,
antifungal,
antiparasitic,
antiviral
Several
studies
been
conducted
combinations
or
crude
extracts
bioactive
investigate
complexity
applications
NEs
carrier
systems
that
overcome
nature
EOs,
which
is
major
factor
limiting
application.
being
progressively
improve
bioavailability
lipophilic
components
EOs.
discusses
these
nonantibiotic
Molecules,
Год журнала:
2022,
Номер
27(17), С. 5584 - 5584
Опубликована: Авг. 30, 2022
Spirulina
is
a
kind
of
blue-green
algae
(BGA)
that
multicellular,
filamentous,
and
prokaryotic.
It
also
known
as
cyanobacterium.
classified
within
the
phylum
algae.
Despite
fact
it
includes
high
concentration
nutrients,
such
proteins,
vitamins,
minerals,
fatty
acids—in
particular,
necessary
omega-3
acids
omega-6
acids—the
percentage
total
fat
cholesterol
can
be
found
in
these
substantially
lower
when
compared
to
other
food
sources.
This
case
even
if
significantly
lower.
In
addition
this,
spirulina
has
bioactive
compounds,
phenols,
phycocyanin
pigment,
polysaccharides,
which
all
take
part
number
biological
activities,
antioxidant
anti-inflammatory
activity.
As
result
its
way
into
formulation
great
medicinal
foods,
functional
nutritional
supplements.
Therefore,
this
article
makes
an
effort
shed
light
on
spirulina,
value
chemical
composition,
applications
some
product
formulations,
dairy
products,
snacks,
cookies,
pasta,
are
at
industrial
level
industry
over
world.
addition,
supports
idea
incorporating
sector,
both
from
health
perspective,
offers
numerous
advantages.
Poultry Science,
Год журнала:
2021,
Номер
101(2), С. 101590 - 101590
Опубликована: Ноя. 9, 2021
In
line
with
the
substantial
increase
in
broiler
industry
worldwide,
Clostridium
perfringens-induced
necrotic
enteritis
(NE)
became
a
continuous
challenge
leading
to
high
economic
losses,
especially
after
banning
antimicrobial
growth
promoters
feeds
by
many
countries.
The
disease
is
distributed
worldwide
either
clinical
or
subclinical
form,
causing
reduction
body
weight
gain
and
feed
conversion
ratio,
impairing
European
Broiler
Index
Production
Efficiency
Factor.
There
are
several
predisposing
factors
development
of
NE.
Clinical
signs
varied
from
inapparent
case
infection
(clostridiosis)
obvious
enteric
(morbidity),
followed
an
mortality
level
(clostridiosis
infection).
laboratory
diagnoses
based
on
history,
signs,
gross
histopathological
lesions,
pathogenic
agent
identification,
serological
testing,
molecular
identification.
Drinking
water
treatment
most
common
route
for
administration
antibiotics,
such
as
penicillin,
bacitracin,
lincomycin.
Strict
hygienic
management
practices
farm,
careful
selection
ingredients
ration
formulation,
use
alternative
antibiotic
additives
all
important
maintaining
efficiency
help
profitability
production.
current
review
highlights
NE
caused
C.
perfringens
explains
advances
understanding
virulence
involved
pathogenesis
special
emphasis
available
alternatives
herbal
extracts
essential
oils
well
vaccines
control
prevention
chickens.
Frontiers in Veterinary Science,
Год журнала:
2022,
Номер
9
Опубликована: Июнь 17, 2022
This
article
aimed
to
describe
the
current
use
scenario,
alternative
feed
additives,
modes
of
action
and
ameliorative
effects
in
broiler
production.
Alternative
additives
have
promising
importance
production
due
ban
on
certain
antibiotics.
The
most
used
antibiotic
alternatives
are
phytogenics,
organic
acids,
prebiotics,
probiotics,
enzymes,
their
derivatives.
Antibiotic
been
reported
increase
intake,
stimulate
digestion,
improve
efficiency,
growth
performance,
reduce
incidence
diseases
by
modulating
intestinal
microbiota
immune
system,
inhibiting
pathogens,
improving
integrity.
Simply,
gut
is
target
raise
health
benefits
growth-promoting
broilers.
Therefore,
naturally
available
for
Then,
summarizing
category,
mode
action,
potential
may
provide
more
informed
decisions
nutritionists,
researchers,
manufacturers,
producers.
Poultry Science,
Год журнала:
2022,
Номер
101(4), С. 101716 - 101716
Опубликована: Янв. 13, 2022
Salmonellosis
is
a
severe
problem
that
threatens
the
poultry
sector
worldwide
right
now.
Salmonella
gallinarium
and
pullorum
(Fowl
typhoid)
are
most
pathogenic
serovars
in
avian
species
leading
to
systemic
infection
resulting
economic
losses
industry.
Nontyphoidal
serotypes
of
(Paratyphoid
disease)
constitute
public
health
hazard
for
their
involvement
food
poisoning
problems
addition
zoonotic
importance.
Also,
distribution
particularly
extensive.
They
resisted
environmental
conditions
made
it
difficult
control
spread
long
time.
Therefore,
current
review
aimed
through
light
on
with
particular
references
its
pathogenesis,
importance,
immune
response
Salmonella,
antibiotics
resistance,
possible
methods
prevention
such
using
promising
alternatives
including
probiotics,
prebiotics,
symbiotics,
organic
acids,
essential
oils,
cinnamaldehyde,
chitosan,
nanoparticles,
vaccines.
PLoS ONE,
Год журнала:
2023,
Номер
18(2), С. e0274679 - e0274679
Опубликована: Фев. 7, 2023
Plant
extract-based
green
synthesis
of
nanoparticles
is
an
emerging
class
nanotechnology
that
has
revolutionized
the
entire
field
biological
sciences.
Green
synthesized
are
used
as
super-growth
promoters
and
antifungal
agents.
In
this
study,
selenium
(SeNPs)
were
using
Melia
azedarach
leaves
extract
main
reducing
stabilizing
agent
characterized
by
UV-visible
spectroscopy,
scanning
electron
microscopy
(SEM),
X-ray
diffraction
(XRD),
energy-dispersive
(EDX),
fourier
transform
infrared
spectrometer
(FTIR).
The
SeNPs
exogenously
applied
on
Mangifera
indica
infected
with
mango
malformation
disease.
at
a
concentration
30
μg/mL
found
to
be
best
which
enhanced
physiological
(chlorophyll
membrane
stability
index),
biochemical
(proline
soluble
sugar)
parameters.
antioxidant
defense
system
was
also
explored,
it
reported
significantly
reduced
biotic
stress
enhancing
enzymatic
non-enzymatic
activities.
vitro
activity
300
inhibited
Fusarium
mangiferae
most.
This
study
considered
first
biocompatible
approach
evaluate
potential
improve
health
malformation-infected
plants
effective
management
strategy
inhibit
growth
F.
mangifera.
Scientific Reports,
Год журнала:
2022,
Номер
12(1)
Опубликована: Июль 12, 2022
Abstract
Selenium
nanoparticles
(Se-NPs)
has
recently
received
great
attention
over
owing
to
their
superior
optical
properties
and
wide
biological
biomedical
applications.
Herein,
crystallographic
dispersed
spherical
Se-NPs
were
green
synthesized
using
endophytic
fungal
strain,
Penicillium
crustosum
EP-1
.
The
antimicrobial,
anticancer,
catalytic
activities
of
biosynthesized
investigated
under
dark
light
(using
Halogen
tungsten
lamp,
100
Watt,
λ
>
420
nm,
intensity
2.87
W
m
−2
)
conditions.
effect
was
dose
dependent
higher
against
Gram-positive
Gram-negative
bacteria
as
well
different
Candida
spp
attained
in
the
presence
than
obtained
Moreover,
viabilities
two
cancer
cells
(T47D
HepG2)
highly
decreased
from
95.8
±
2.9%
93.4
3.2%
those
84.8
46.4
3.3%
light-irradiation
conditions,
respectively.
Significant
decreases
IC
50
values
T47D
HepG2
at
109.1
3.8
70.4
2.5
µg
mL
−1
,
respectively
conditions
19.7
7.2
4.8
4.2
after
exposure
light-irradiation.
photoluminescence
activity
revealed
methylene
blue
degradation
efficiency
89.1
2.1%
210
min
UV-irradiation
compared
59.7
0.2%
68.1
1.03%
stability
efficient
MB
successfully
achieved
for
least
five
cycles.
Frontiers in Immunology,
Год журнала:
2023,
Номер
14
Опубликована: Янв. 31, 2023
Increase
in
drug
resistance
as
well
ineffective
immunization
efforts
against
various
pathogens
(viruses,
bacteria
and
fungi)
pose
a
significant
threat
to
the
poultry
industry.
Spirulina
is
one
of
most
widely
used
natural
ingredients
which
becoming
popular
nutritional
supplement
humans,
animals,
aquaculture.
It
contains
protein,
vitamins,
minerals,
fatty
acids,
pigments,
essential
amino
acids.
Moreover,
it
also
has
considerable
quantities
unique
antioxidants
including
polyphenols,
carotenoids,
phycocyanin.
Dietary
supplementation
can
beneficially
affect
gut
microbial
population,
serum
biochemical
parameters,
growth
performance
chicken.
Additionally,
polyphenolic
contents
having
antibacterial
effects.
extracts
might
inhibit
bacterial
motility,
invasion,
biofilm
formation,
quorum
sensing
addition
acting
directly
on
bacterium
by
weakening
making
cell
walls
more
porous,
subsequently
resulting
cytoplasmic
content
leakage.
shown
antiviral
activities
certain
common
human
or
animal
viruses
this
capability
be
considered
exhibit
potential
benefits
avian
also.
Spirulan,
calcium-rich
internal
polysaccharide
Spirulina,
potentially
responsible
for
its
effect
through
inhibiting
entry
several
into
host
cells,
boosting
production
nitric
oxide
macrophages,
stimulating
generation
cytokines.
Comparatively
greater
emphasis
been
given
immune
modulatory
effects
feed
additive
chicken
boost
disease
improve
survival
rates,
particularly
under
stress
conditions.
This
manuscript
reviews
biological
immune-stimulating
properties
use
dietary
enhance
growth,
health
resistance.
Life,
Год журнала:
2023,
Номер
13(3), С. 845 - 845
Опубликована: Март 21, 2023
Arthrospira
platensis
is
a
filamentous
cyanobacterium
of
the
class
Cyanophyceae
and
most
cultivated
photosynthetic
prokaryote.
It
used
in
pharmaceutical
sector,
medicine
food
industry.
has
rich
micro-
macro-element
composition,
containing
proteins,
lipids,
carbohydrates,
essential
amino
acids,
polyunsaturated
fatty
minerals
raw
fibers.
commonly
ingredient
products
nutritional
supplements.
The
wide
range
biologically
active
components
determines
its
diverse
pharmacological
properties
(antioxidant,
antidiabetic,
antimicrobial,
antineoplastic,
antitumor,
anti-inflammatory,
photoprotective,
antiviral,
etc.).
This
review
summarizes
research
related
to
taxonomy,
distribution
chemical
composition
as
well
potential
application
industries.
Attention
drawn
various
medical
applications
an
antidiabetic
antiobesity
agent,
with
hepatoprotective,
antimicrobial
antiviral
effects
regulatory
on
neurodegenerative
diseases.
Abstract
Background
As
antibiotics
and
chemotherapeutics
are
no
longer
as
efficient
they
once
were,
multidrug
resistant
(MDR)
pathogens
cancer
presently
considered
two
of
the
most
dangerous
threats
to
human
life.
In
this
study,
Selenium
nanoparticles
(SeNPs)
biosynthesized
by
Streptomyces
parvulus
MAR4,
nano-chitosan
(NCh),
their
nanoconjugate
(Se/Ch-nanoconjugate)
were
suggested
be
efficacious
antimicrobial
anticancer
agents.
Results
SeNPs
MAR4
NCh
successfully
achieved
conjugated.
The
spherical
with
a
mean
diameter
94.2
nm
high
stability.
Yet,
Se/Ch-nanoconjugate
was
semispherical
74.9
much
higher
SeNPs,
NCh,
showed
significant
activity
against
various
microbial
strong
inhibitory
effect
on
tested
metabolic
key
enzymes
[phosphoglucose
isomerase
(PGI),
pyruvate
dehydrogenase
(PDH),
glucose-6-phosphate
(G6PDH)
nitrate
reductase
(NR)];
powerful
agent.
Furthermore,
revealed
cytotoxicity
HepG2
(IC
50
=
13.04
μg/ml)
moderate
toxicity
Caki-1
(HTB-46)
tumor
cell
lines
21.35
but
low
WI-38
normal
line
85.69
μg/ml).
Nevertheless,
displayed
substantial
IC
values
11.82
7.83
μg/ml,
respectively.
Consequently,
may
more
easily
absorbed
both
lines.
However,
it
exhibited
very
153.3
μg/ml.
Therefore,
presented
activity.
Conclusion
convincingly
recommended
used
in
biomedical
applications
versatile
potent
agents
ensuring
notable
levels
biosafety,
environmental
compatibility,
efficacy.