Polymers,
Год журнала:
2021,
Номер
13(4), С. 633 - 633
Опубликована: Фев. 20, 2021
Biopolymers
have
gained
tremendous
attention
in
many
daily
life
applications,
including
medical
the
past
few
years.
Obstetrics
and
gynecology
are
two
fields
dealing
with
sensitive
parts
of
woman's
body
her
newborn
baby,
which
normally
associated
issues
such
as
toxicity,
infections,
even
gene
alterations.
Medical
professions
that
use
screening,
examination,
pre,
post-operation
materials
should
benefit
from
a
better
understanding
each
type
material's
characteristics,
health,
environmental
effects.
The
underlying
principles
biopolymer-based
for
different
obstetric
gynecologic
applications
may
discover
various
advantages
benefits
using
materials.
This
review
presents
health
impact
conventional
polymer-based
on
pregnant
women's
highlights
potential
biopolymers
safer
option.
recent
works
utilizing
presented
this
review,
includes
suture
surgeries,
cosmetic
personal
care
products,
vaginal
drug
delivery;
well
wound
dressing
healing
main
challenges
applications.
Pharmaceutics,
Год журнала:
2023,
Номер
15(4), С. 1313 - 1313
Опубликована: Апрель 21, 2023
Chitosan,
a
biocompatible
and
biodegradable
polysaccharide
derived
from
chitin,
has
surfaced
as
material
of
promise
for
drug
delivery
biomedical
applications.
Different
chitin
chitosan
extraction
techniques
can
produce
materials
with
unique
properties,
which
be
further
modified
to
enhance
their
bioactivities.
Chitosan-based
systems
have
been
developed
various
routes
administration,
including
oral,
ophthalmic,
transdermal,
nasal,
vaginal,
allowing
targeted
sustained
release
drugs.
Additionally,
used
in
numerous
applications,
such
bone
regeneration,
cartilage
tissue
cardiac
corneal
periodontal
wound
healing.
Moreover,
also
utilized
gene
delivery,
bioimaging,
vaccination,
cosmeceutical
Modified
derivatives
improve
biocompatibility
resulting
innovative
promising
potentials
This
article
summarizes
the
recent
findings
on
its
application
science.
Journal of Materials Research and Technology,
Год журнала:
2021,
Номер
15, С. 2287 - 2316
Опубликована: Сен. 13, 2021
Recently,
the
demand
for
biodegradable,
eco-friendly
and
sustainable
alternatives
has
been
on
increase.
Although
numerous
biopolymers
such
as
cellulose,
starch,
plants
proteins
polylactic
acid,
etc.,
have
used
to
produce
bioplastics,
outcomes
need
more
improvement
suit
different
applications.
This
paper
comprehensively
maps
expanding
academic
territory
using
lignin
a
reinforcement
material
improve
biopolymers-based
materials'
properties.
A
brief
discussion
chronological
development
of
lignin,
types,
isolation,
physical
chemical
modifications
was
presented.
Also,
role
in
biopolymeric
blends
acids,
proteins,
polyhydroxy
butyrate
polyamides
reviewed.
Finally,
review
extensively
critically
discusses
current
findings
lignin/biopolymers
various
industrial
applications,
including
wood
adhesives,
adsorbent
toxic
heavy
metal
removal,
production
carbon
materials,
dispersant
medium,
flame
retardant
storage
highlighted
possible
applications
biofuel,
hydrocarbon,
lubricant,
renewable
chemical,
smart
materials.
Cancers,
Год журнала:
2023,
Номер
15(10), С. 2721 - 2721
Опубликована: Май 11, 2023
Cancer
is
among
the
current
leading
causes
of
death
worldwide,
despite
novel
advances
that
have
been
made
toward
its
treatment,
it
still
considered
a
major
public
health
concern.
Considering
both
serious
impact
cancer
on
and
significant
side
effects
complications
conventional
therapeutic
options,
strategies
towards
targeted
therapy
must
be
enhanced
to
avoid
undesired
toxicity.
immunotherapy
has
become
preferable
researchers
in
recent
years
compared
such
as
chemotherapy,
surgery,
radiotherapy.
The
understanding
how
control
immune
checkpoints,
develop
vaccines,
genetically
modify
cells
well
enhance
activation
antitumor
response
led
development
treatments.
In
this
review,
we
address
molecular
mechanisms.
Different
immunotherapeutic
approaches
are
critically
discussed,
focusing
challenges,
potential
risks,
prospects
involving
their
use.
Pharmaceutics,
Год журнала:
2023,
Номер
15(3), С. 868 - 868
Опубликована: Март 7, 2023
The
new
era
of
nanomedicine
offers
significant
opportunities
for
cancer
diagnostics
and
treatment.
Magnetic
nanoplatforms
could
be
highly
effective
tools
diagnosis
treatment
in
the
future.
Due
to
their
tunable
morphologies
superior
properties,
multifunctional
magnetic
nanomaterials
hybrid
nanostructures
can
designed
as
specific
carriers
drugs,
imaging
agents,
theranostics.
Multifunctional
are
promising
theranostic
agents
due
ability
diagnose
combine
therapies.
This
review
provides
a
comprehensive
overview
development
advanced
combining
optical
providing
photoresponsive
platforms
medical
applications.
Moreover,
this
discusses
various
innovative
developments
using
nanostructures,
including
drug
delivery,
treatment,
tumor-specific
ligands
that
deliver
chemotherapeutics
or
hormonal
resonance
imaging,
tissue
engineering.
Additionally,
artificial
intelligence
(AI)
used
optimize
material
properties
based
on
predicted
interactions
with
cell
membranes,
vasculature,
biological
fluid,
immune
system
enhance
effectiveness
therapeutic
agents.
Furthermore,
an
AI
approaches
assess
practical
utility
Finally,
presents
current
knowledge
perspectives
systems
models.
Pharmaceutics,
Год журнала:
2023,
Номер
15(3), С. 744 - 744
Опубликована: Фев. 23, 2023
Cancer
is
the
leading
cause
of
death,
acting
as
a
global
burden,
severely
impacting
patients’
quality
life
and
affecting
world
economy
despite
expansion
cumulative
advances
in
oncology.
The
current
conventional
therapies
for
cancer
which
involve
long
treatment
duration
systemic
exposure
drugs
leads
to
premature
degradation
drugs,
massive
amount
pain,
side
effects,
well
recurrence
condition.
There
also
an
urgent
demand
personalized
precision-based
medicine,
especially
after
recent
pandemic,
avoid
future
delays
diagnosis
or
treatments
patients
they
are
very
essential
reducing
mortality
rate.
Recently,
microneedles
consist
patch
with
tiny,
micron-sized
needles
attached
it
have
been
quite
sensation
emerging
technology
transdermal
application
diagnose
treat
various
illnesses.
being
extensively
studied
offer
myriad
benefits,
since
microneedle
patches
better
approach
through
self
administration,
painless
treatment,
economically
environmentally
friendly
comparison
other
methods.
gains
from
significantly
improves
survival
rate
patients.
emergence
versatile
innovative
drug
delivery
systems
presents
prime
breakthrough
opportunity
safer
more
effective
therapies,
could
meet
demands
different
scenarios.
This
review
highlights
types
microneedles,
fabrication
methods
materials,
along
opportunities.
In
addition,
this
addresses
challenges
limitations
therapy
solutions
studies
works
facilitate
clinical
translation
therapies.
Scientia Pharmaceutica,
Год журнала:
2025,
Номер
93(1), С. 6 - 6
Опубликована: Янв. 22, 2025
Novel
therapies
are
required
due
to
the
rising
cancer
burden.
Conventional
chemotherapeutics
tend
be
particularly
toxic,
but
there
is
a
promising
alternative
for
oncogenes,
such
as
c-MYC.
Often
overexpressed
in
many
types,
potential
c-MYC
oncogene
seems
essential
development
of
cancer.
Targeting
protein
directly
was
limited,
these
DNA
structures
composed
guanine-rich
sequences
suppress
transcription.
This
review
discusses
recent
advances
developing
small
compounds
that
selectively
bind
and
stabilize
G-quadruplexes
(G4).
These
molecules
have
also
shown
promise
inhibition
signaling
tumor
growth,
suggesting
G-quadruplex
targeting
could
therapeutic
