Exploration the Effects of Mesenchymal Stem Cells and Olive Leaf Extract on Physiological and Histopathological Changes on the Kidney of Diabetes Rats DOI Creative Commons

Mervat Ahmed AbdRabou,

Ahmed Atwa, Zahrah R Alrayes

и другие.

Cellular Physiology and Biochemistry, Год журнала: 2024, Номер 58(6), С. 807 - 822

Опубликована: Дек. 28, 2024

Background/Aims: Gestational Diabetes Mellitus (GDM) is a common complication during pregnancy, defined as diabetes diagnosed in the second or third trimester, often asymptomatic. This study investigates therapeutic potential of olive leaf extracts and stem cells mitigating GDM-induced complications, particularly focusing on renal function, oxidative stress, pancreatic cell regeneration. Methods: Measurements were made gravid female rats with without intraperitoneal administration Streptozotocin (35 mg/kg body weight). Biochemical analyses conducted to evaluate function markers (urea, uric acid, creatinine) stress parameters (malondialdehyde, glutathione, superoxide dismutase levels). Histopathological immunohistopathological evaluations kidney tissues performed using hematoxylin eosin staining specific (p53, Insulin, PCNA) assess cellular changes. Results: The diabetic group exhibited significantly elevated levels urea, creatinine (p<0.01) compared control group. Treatment reduced these levels. Malondialdehyde but showed marked improvement treatment groups. Additionally, glutathione activities diminished (p<0.05) increased following treatment. revealed regeneration improved tissue morphology groups Conclusion: Stem exhibit significant ameliorating dysfunction, damage associated GDM, highlighting their role enhancing

Язык: Английский

Nitrites in Meat Products in Serbia: Harmful or Safe? DOI Creative Commons
Jasna Kureljušić, Jelena Maletić, Slavoljub Stanojević

и другие.

Foods, Год журнала: 2025, Номер 14(3), С. 489 - 489

Опубликована: Фев. 3, 2025

Nitrate and nitrite, commonly added to meat products as sodium or potassium salts, serve multiple functions such developing characteristic flavor, inhibiting microbial growth, controlling rancidity by preventing lipid oxidation. Nitrites are recognized for their potential health risks humans. The present research aimed determine the amount of nitrite in four product categories Serbia over a period from 2015 2021. A total 923 samples were analyzed, including 293 finely chopped sausages, 203 coarsely 160 canned meats, 267 smoked meats. category consisted eight distinct products, pork ribs, sirloin, chicken drumsticks. An ISO 2918 method was used measure content. average content, expressed (NaNO2), found be 61.5 mg/kg 57.6 48.4 meat, 41.8 meat. results collectively demonstrate concentrations within regulatory limits. In conclusion, all tested below maximum allowable limits per national European regulations, ensuring compliance with safety standards while highlighting importance continuous monitoring mitigate public risks.

Язык: Английский

Процитировано

1

Pulsed light and jabuticaba peel extract for nitrite reduction and quality enhancement in sliced mortadella DOI

Priscila Rossato Fracari,

Igor Tomašević, Ana Guimarães Massia

и другие.

Meat Science, Год журнала: 2025, Номер unknown, С. 109777 - 109777

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

Impact of pectin-based sachets with olive and guava leaf extracts on chicken powder stock properties DOI
Mohammed Sabbah, Asmaa Al-Asmar,

Yara Jaradat

и другие.

Journal of Plastic Film & Sheeting, Год журнала: 2025, Номер unknown

Опубликована: Апрель 22, 2025

This research explores the development of sustainable food packaging alternatives using olive and guava leaf extracts added into pectin (PEC)-based edible films. These films were used to create a sachet containing chicken stock powder (CSP). Specifically, PEC was combined with 0.2% (w/v) extract (OLE) or (GLE) along 30% glycerol as plasticizer. Physical, microbial, sensory properties at different storage times after PEC-based packaged (CSP) evaluated. The results showed that sachets OLE GLE inhibited microbial growth when compared control (PEC only). FTIR analysis revealed significant interactions between bioactive compounds from GLE, evidenced by shifts in O-H C = O stretching regions. Moreover, CSP moisture content significantly reduced 20 days storage. color remained consistent all throughout this study. Additionally, soup viscosity obtained dissolving 18 g lower than control. Sensory soups made had better texture unpackaged sachets. suggest including is promising, functional approach. innovative approach offers potential solution address environmental concerns related plastic materials.

Язык: Английский

Процитировано

0

Chitosan-based materials for food preservation: Enhancing shelf life and safety through sustainable nanoparticles and films DOI
Tarsila Tuesta,

Angie Castillo-Barzola,

Henry Linares

и другие.

Food Chemistry, Год журнала: 2025, Номер 486, С. 144589 - 144589

Опубликована: Май 5, 2025

Язык: Английский

Процитировано

0

Assessment of Pyracantha fortuneana fruit extract as a nitrite substitute on the physicochemical properties, sensorial profile, safety risks and functional properties of fermented beef sausages DOI Creative Commons

Zhaoyang Song,

Yinjuan Cao,

Jia Pei

и другие.

LWT, Год журнала: 2024, Номер 200, С. 116203 - 116203

Опубликована: Май 1, 2024

This study aimed to investigate the effect of Pyracantha fortuneana fruit extract (PFE) as a nitrite substitute on quality, flavor, contents biogenic amines and formation antioxidant peptides fermented beef sausages during storage. Compared with control group, treated PFE showed elevated L* a* values, enhanced activity, increased resistance microbial growth lipid protein oxidation. In particular, there were 2.44 ± 0.02 mg MDA/kg thiobarbituric acid reactive substances after 35 d. Interestingly, had positive texture, protection that was superior nitrite. not only improved microstructure sausage but also delayed degradation myofibrillar sarcoplasmic proteins shown in SDS-PAGE analysis, which resulted significant improvement flavor reduction (P < 0.05). The LC-MS/MS results PFE-treated significantly promoted peptide high 2,2-diphenyl-1-picrylhydrazyl radical scavenging ferric ion reducing power Therefore, has potential be effective promising for industrial production application sausages.

Язык: Английский

Процитировано

3

Preliminary Exploration of Natural Polyphenols and/or Herbal Mix Replacing Sodium Nitrate to Improve the Storage Quality of Pork Sausage DOI Creative Commons

Angeliki-Niki Kaloudi,

Agori Karageorgou, Michael Goliomytis

и другие.

Applied Sciences, Год журнала: 2025, Номер 15(2), С. 789 - 789

Опубликована: Янв. 15, 2025

Synthetic agents are regularly used as preservatives in pork meat products such sausages. However, these compounds can be harmful to human health, due their carcinogenic potential. As a result, natural antioxidants derived from herbs and medicinal plants continuously thoroughly assessed replace/minimize the application of synthetic during processing storage. The current study was consequently implemented highlight effects polyphenols and/or an herbal mix on quality characteristics Five batches sausages were manufactured using same recipe raw materials; control, without sodium nitrate (CON), four groups supplemented with at 0.015% (SN), olive 0.2% (POL), containing rosemary, savory, camelia, thyme, lemon balm turmeric (NM), or concomitant addition (0.1%) (POL + NM). Assessment pH, color, cooking loss, tenderness oxidative stability immediately after manufacture (day 0) 1, 2 3 months refrigerated It illustrated that ameliorated consequence POL or/and NM addition, since values malondialdehyde (MDA) significantly decreased compared control (p < 0.001) 3, similar those observed SN group served positive control. Values for lightness (L), shear force loss among experimental treatments > 0.05). On other hand, pH greater than Redness (a*) higher yellowness (b*) 0.001). concluded examined could alternative nitrates amelioration

Язык: Английский

Процитировано

0

Changes in quality parameters of ripened sausages added with olive leaf extract during refrigerated storage under modified atmosphere DOI Creative Commons
Michela Pia Totaro, Graziana Difonzo,

Gabriele VENTRELLA

и другие.

LWT, Год журнала: 2025, Номер unknown, С. 117483 - 117483

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

The latest advances on the formation, exposure level and control strategies of nitrosamines in meat, poultry and fish products DOI
Mengjing Guo, Yanping Xian, Xiaojuan Zhao

и другие.

Food Chemistry, Год журнала: 2025, Номер 488, С. 144837 - 144837

Опубликована: Май 19, 2025

Язык: Английский

Процитировано

0

Exploration the Effects of Mesenchymal Stem Cells and Olive Leaf Extract on Physiological and Histopathological Changes on the Kidney of Diabetes Rats DOI Creative Commons

Mervat Ahmed AbdRabou,

Ahmed Atwa, Zahrah R Alrayes

и другие.

Cellular Physiology and Biochemistry, Год журнала: 2024, Номер 58(6), С. 807 - 822

Опубликована: Дек. 28, 2024

Background/Aims: Gestational Diabetes Mellitus (GDM) is a common complication during pregnancy, defined as diabetes diagnosed in the second or third trimester, often asymptomatic. This study investigates therapeutic potential of olive leaf extracts and stem cells mitigating GDM-induced complications, particularly focusing on renal function, oxidative stress, pancreatic cell regeneration. Methods: Measurements were made gravid female rats with without intraperitoneal administration Streptozotocin (35 mg/kg body weight). Biochemical analyses conducted to evaluate function markers (urea, uric acid, creatinine) stress parameters (malondialdehyde, glutathione, superoxide dismutase levels). Histopathological immunohistopathological evaluations kidney tissues performed using hematoxylin eosin staining specific (p53, Insulin, PCNA) assess cellular changes. Results: The diabetic group exhibited significantly elevated levels urea, creatinine (p<0.01) compared control group. Treatment reduced these levels. Malondialdehyde but showed marked improvement treatment groups. Additionally, glutathione activities diminished (p<0.05) increased following treatment. revealed regeneration improved tissue morphology groups Conclusion: Stem exhibit significant ameliorating dysfunction, damage associated GDM, highlighting their role enhancing

Язык: Английский

Процитировано

1