Journal of Microencapsulation,
Год журнала:
2024,
Номер
unknown, С. 1 - 12
Опубликована: Дек. 23, 2024
Plant-derived
extracellular
vesicles
(EVs)
are
natural
nanovesicles
for
drug
delivery.
This
study
isolated
and
characterised
EVs
from
medicinal
plants
as
delivery
vehicles.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(20), С. 11092 - 11092
Опубликована: Окт. 15, 2024
Mineralization
is
a
key
biological
process
that
required
for
the
development
and
repair
of
tissues
such
as
teeth,
bone
cartilage.
Exosomes
(Exo)
are
subset
extracellular
vesicles
(~50–150
nm)
secreted
by
cells
contain
genetic
material,
proteins,
lipids,
nucleic
acids,
other
substances
have
been
extensively
researched
oral
tissue
regeneration.
However,
Exo-free
biomaterials
or
exosome
treatments
exhibit
poor
bioavailability
lack
controlled
release
mechanisms
at
target
site
during
By
encapsulating
Exos
into
like
hydrogels,
these
disadvantages
can
be
mitigated.
Several
engineering
approaches,
those
wound
healing
processes
in
diabetes
mellitus,
treatment
osteoarthritis
(OA)
cartilage
degeneration,
intervertebral
disc
cardiovascular
diseases,
etc.,
exploited
to
deliver
exosomes
containing
variety
therapeutic
diagnostic
cargos
tissues.
Despite
significant
efficacy
Exo-laden
their
use
mineralized
tissues,
tissue,
very
sparse.
This
review
aims
explore
summarize
literature
related
potential
hydrogel-encapsulated
provides
insight
practical
procedures
future
clinical
techniques.
Research Square (Research Square),
Год журнала:
2024,
Номер
unknown
Опубликована: Апрель 16, 2024
Abstract
We
present,
a
facile
method
for
the
synthesis
of
block
co-polymer
[(PLA)-b-(Car)],
(PLA-Poly
Lactic
acid
and
Car-Carbazole)
followed
by
development
cone
ice-cream
cup-shaped
frustums
with
nanoporous
capsules
bio-sensing
drug
loading
applications.
Thermoplastic
polyester
PLA
aminated
an
aromatic
heterocyclic
organic
compound
Car
gives
desired
shape
characteristics
extended
porosity
on
surface.
The
size,
shape,
morphology
are
tunable
concerning
solvents
thermal
treatment.
Interestingly,
hollow
(half-broken
coconut
type)
has
been
carried
out
without
using
any
precursors
surfactants.
Synthesis
[(PLA)-b-(Car)]
confirmed
through
Fourier
transform
infrared
(FTIR),
nuclear
magnetic
resonance
(NMR;
1H
13C).
However,
surface
properties
were
field
emission
scanning
electron
microscopy
(FE-SEM),
Bruner
Emmett
Teller
(BET),
atomic
force
(AFM)
characterizations.
capsule
size
ranges
from
~200
nm
to
1
µm
(in
diameter)
scales
~60
80
nm.
porous
biosensing
biomedical
applications
can
be
considered
as
unique
novel
characteristic
property
our
invention.
This
kind
ice
cream
used
stimuli-responsive
catalytic
activity
fluorescence
measurement
cysteine
gold
nanoparticle
[(Cys)-(Au+)]
enhanced
payload
Journal of Microencapsulation,
Год журнала:
2024,
Номер
unknown, С. 1 - 12
Опубликована: Дек. 23, 2024
Plant-derived
extracellular
vesicles
(EVs)
are
natural
nanovesicles
for
drug
delivery.
This
study
isolated
and
characterised
EVs
from
medicinal
plants
as
delivery
vehicles.