Separation Science Plus,
Год журнала:
2024,
Номер
7(3)
Опубликована: Янв. 7, 2024
Abstract
Solvent‐assisted
dispersive
solid‐phase
extraction
(SA‐DSPE)
approach
was
developed
to
measure
triazole
fungicides
(TFs).
In
the
SA‐DSPE
technique,
addition
of
1000
μL
ethanol
as
a
disperser
solvent,
along
with
small
quantity
benzil
sorbent
sample
solution,
led
cloudy
solution.
After
completion
extraction,
mixture
subjected
centrifugation
isolate
benzil.
Next,
dissolved
in
ethanol,
and
resulting
solution
subsequently
analyzed
by
gas
chromatography‐flame
ionization
detector.
This
method
demonstrated
high
linearity
(R
2
>
0.9963)
repeatability
(relative
standard
deviation
%
<
4.3)
for
quantification
TFs
under
optimal
conditions
(sorbent:
benzil,
amount
benzil:
2%
w/v,
pH
solution:
7.0,
solvent:
volumes
ethanol:
μL,
centrifuge
time:
3
min,
temperature:
25°C,
ionic
strength:
without
salt
addition).
The
proposed
yielded
detection
limits,
preconcentration
factors
within
ranges
0.3–0.9
ng/mL,
1.0–3.0
419–426,
respectively.
Finally,
validated
employed
determine
diverse
range
real
samples,
encompassing
waters,
fruits,
vegetables,
agricultural
soils,
relative
recoveries
ranging
from
93.0%
104%.
Foods,
Год журнала:
2024,
Номер
13(6), С. 866 - 866
Опубликована: Март 13, 2024
The
amount
of
macrolide
(MAL)
residues
in
aquatic
products,
including
oleandomycin
(OLD),
erythromycin
(ERM),
clarithromycin
(CLA),
azithromycin
(AZI),
kitasamycin
(KIT),
josamycin
(JOS),
spiramycin
(SPI),
tilmicosin
(TIL),
tylosin
(TYL),
and
roxithromycin
(ROX),
was
determined
using
solid-phase
extraction
ultra-performance
liquid
chromatography–tandem
mass
spectrometry
(UPLC-MS/MS).
were
extracted
with
1%
ammonia
acetonitrile
solution
purified
by
neutral
alumina
adsorption.
Chromatographic
separation
completed
on
an
ACQUITY
UPLC
BEH
C18
column
acetonitrile–0.1%
formic
acid
aqueous
as
the
mobile
phase,
detection
performed
multiple
reaction
monitoring
scanning
positive
mode
electrospray
ion
source
(ESI+).
Five
isotopically
labeled
compounds
used
internal
standards
for
quality
control
purposes.
findings
indicated
that
across
concentration
span
1.0–100
μg/L,
there
a
strong
linear
correlation
(R2
>
0.99)
between
instrumental
response
10
MALs.
limit
UPLC-MS/MS
0.25–0.50
μg/kg,
quantitation
0.5–1.0
μg/kg.
added
recovery
blank
matrix
samples
at
standard
gradient
levels
(1.0,
5.0,
50.0
μg/kg)
83.1–116.6%,
intra-day
precision
inter-day
precisions
3.7
13.8%,
respectively.
method
is
simple
fast,
high
accuracy
good
repeatability,
line
requirements
accurate
qualitative
quantitative
analysis
MALs
products.
