Chemoprofiling and medicinal potential of underutilized leaves of Cyperus scariosus
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Март 27, 2024
Abstract
Agro-waste
is
the
outcome
of
under-utilization
bioresources
and
a
lack
knowledge
to
re-use
this
waste
in
proper
ways
or
circular
economy
approach.
In
Indian
medicinal
system,
root
Cyperus
scariosus
(CS)
used
at
large
scale
due
their
vital
properties.
Unfortunately,
aerial
part
CS
treated
as
agro-waste
an
under-utilized
bioresource.
Due
knowledge,
weed.
This
present
study
first
ever
attempt
explore
leaves
medicinally
nutrient
rich
source.
To
determine
food
nutritional
values
neglected
R.Br.
(CS),
i.e.
leaves,
phytochemicals
metal
ions
were
quantified
by
newly
developed
HPLC
ICPOES-based
methods.
The
content
observed
analysis
for
caffeic
acid,
catechin,
epicatechin,
trans-p-coumaric
trans-ferulic
acid
was
10.51,
276.15,
279.09,
70.53,
36.83
µg/g,
respectively.
GC–MS/MS
analysis,
fatty
acids
including
linolenic
phytol,
palmitic
etc.
identified.
ICPOES
significant
Na,
K,
Ca,
Cu,
Fe,
Mg,
Mn,
Zn
observed.
TPC
TFC
17.933
mg
GAE
eq./g
130.767
QCE
along
with
IC
50
value
2.78
mg/mL
DPPH
assay
better
antacid
activity
measured
than
standard
(CaCO
3
).
methanolic
extract
showed
anti-microbial
against
Staphylococcus
aureus
(15
±
2
mm),
Pseudomonas
aeruginosa
(12
mm)
Escherichia
coli
(10
mm).
silico
studies
confirmed
vitro
results
obtained
from
antioxidant,
antiacid,
studies.
addition,
revealed
anti-cancerous
anti-inflammatory
potential
leaves.
study,
thus,
demonstrated
significance
conversion
into
mankind
pharmaceutical
potent
material.
Consequently,
highlighted
that
have
importance
good
utility
industry
improving
bio-valorization
environment.
Язык: Английский
Simultaneously quantification of eight marker compounds by HPLC, and HPTLC analysis for the marker-based shelf-life kinetic study for the standardization of polyherbal drug AYUSH SG-5, medicinal properties and computational studies
Microchemical Journal,
Год журнала:
2024,
Номер
199, С. 109958 - 109958
Опубликована: Янв. 10, 2024
Язык: Английский
A Comparative Analysis of Phytochemicals, Metal Ions, Volatile Metabolites in Heart Wood, Stem Bark and Leaves of Salix alba L. along with in Vitro Antioxidant, Antacid, Antimicrobial Activities for Sake of Environment Conservation by Substitution of Stem Bark With Leaf
Chemistry & Biodiversity,
Год журнала:
2023,
Номер
20(12)
Опубликована: Окт. 23, 2023
The
genus
of
Salix
is
used
in
food,
medicine
and
nutraceuticals,
standardized
by
using
the
single
marker
compound
Salicin
only.
Stem
bark
official
part
for
preparation
various
drugs,
nutraceuticals
food
products,
which
may
lead
to
overexploitation
damage
tree.
There
need
search
substitution
stem
with
leaf
alba
L.
(SA),
yet
not
reported.
Comparative
phytochemicals
viz.
Salicin,
Procyanidin
B1
Catechin
were
quantified
parts
SA
heart
wood
(SA-HW),
(SA-SB)
leaves
(SA-L)
L.by
newly
developed
HPLC
method.
It
was
observed
that
SA-HW
SA-L
contained
far
better
amount
B
as
compared
SA-SB
(SA-HW~SA-L≫SA-SB).
Essential
toxic
metal
ions
all
three
analysed
ICP-OES
method,
where
founded
a
rich
source
micronutrients
essential
SA-HW.
GC-MS
analysis
has
shown
presence
fatty
acids
volatile
compounds.
TPC
TFC
values
ranged
from
2.69
32.30
mg
GAE/g
wt.
37.57
220.76
QCE/g
respectively.
In
DPPH
assay
IC50
SA-SB,
SA-HW,
1.09
(±0.02),
5.42
(±0.08),
8.82
(±0.10)
mg/mL,
order
antibacterial
activities
against
E.
coli,
S.
aureus,
P.
aeruginosa,
B.
subtilis
strains
SA-L>SA-HW>SA-SB
strong
strains.
antacid
SA-L>SA-SB>SA-HW.
have
significant
nutrients,
medicinal
properties
than
SA-SB.
be
considered
substitute
save
environment
or
avoid
over
exploitation,
but
after
complete
pharmacological
toxicological
studies.
Язык: Английский
Effects of geographical variation on the phytochemicals gallic acid, corilagin, and ellagic acid, as well as medicinal properties of Emblica officinalis Gaertn (Fruit)
Food and Humanity,
Год журнала:
2024,
Номер
3, С. 100372 - 100372
Опубликована: Авг. 8, 2024
Язык: Английский
A Review on the Traditional Applications, Phytochemistry, and Pharmacology of the Genus Physochlaina G. Don
Chemistry & Biodiversity,
Год журнала:
2024,
Номер
21(6)
Опубликована: Март 26, 2024
Physochlaina
is
a
genus
of
flowering
plants
belonging
to
the
family
Solanaceae
and
consists
10
species
distributed
in
various
Asian
countries.
The
have
been
traditionally
used
cure
variety
illnesses
due
their
highly
valuable
medicinal
properties,
including
cancer,
asthma,
cough,
weakness,
stomachache,
diarrhea,
swelling,
spasms,
toothache,
boils,
ulcers,
rheumatic
pain,
chronic
bronchitis,
gastric
problems,
abdominal
palpitation,
insomnia.
gained
significant
attention
remarkable
ethnopharmacological
ethnomedicinal
significance.
researchers
isolated
so
far
71
biologically
active
secondary
metabolites
from
different
species,
which
include
flavonoids,
alkaloids,
coumarins,
phenolic
acids,
iridoids,
sterols.
These
compounds
exhibit
diverse
biological
activities,
such
as
antibacterial,
anti-oxidant,
anti-inflammatory,
cytotoxic,
anticancer
properties.
present
review
has
compiled
with
intention
providing
comprehensive
overview
botany,
distribution,
traditional
uses,
phytochemical
profile,
activities
for
future
exploration
plant-based
drugs
therapeutic
approaches.
contributes
understanding
pharmacological
potential
unraveling
chemical
composition,
highlighting
relevance
developing
agents.
Till
date,
numerous
properties
phytochemicals
that
support
ethnobotanical
history
documented
number
scientific
publications.
However,
greater
emphasis
should
be
paid
vivo
investigations
on
extracts
phytoconstituents
well
mechanistic
analysis
help
drug
developers
better
understand
how
use
resources
herbal
formulations
using
techniques.
Язык: Английский
Analytical method development and validation for simultaneous estimation of seven markers in polyherbal formulation JKC by using RP-HPLC
Future Journal of Pharmaceutical Sciences,
Год журнала:
2024,
Номер
10(1)
Опубликована: Июль 29, 2024
Abstract
Background
The
RP-HPLC
method
has
been
established
to
simultaneous
estimation
of
seven
markers
in
polyherbal
formulation
JKC
using
the
C
18
(25
×
0.46
cm,
i.d,5
µm)
column.
mobile
phase
consisted
methanol:
water
(80:20)
at
a
flow
rate
1.0
mL/min
and
observed
retention
time
2
11
min
with
sharp
points.
marker
compounds
viz.
Andrographolide
(AG),
Piperine
(PP),
Picroside-I
(P-I),
Picroside-II
(P-II),
α-Cyprone
(AC),
6-Shogaol
(6S),
6-Gingerol
(6G)
were
quantified
formulations
by
HPLC
method.
Detection
was
performed
wavelength
(λ)
229
nm
for
AG,
343
PP,
279
P-I,
264
P-II,
254
AC,
280
both
6S
6G
HPLC–PDA
detector.
Results
different
times
(R
t
)
i.e.
AG
3.060
±
0.01
min,
PP
5.460
0.03
P-I
2.789
0.02
P-II
2.553
AC
10.951
6.302
4.111
respectively.
proposed
validated
acceptable
linearity
(r
0.9995–0.9999),
precision,
robustness,
ruggedness,
accuracy
(RSD
<
2%)
under
optimum
conditions.
limit
detection
quantification
bioactive
as:
(1.386;
4.200
ppm),
(2.033;
6.161
(2.822;
8.553
(2.538;
7.691
(0.269;
0.815
(0.158;
0.480
(0.188;
0.569
ppm).
amount
(mg/g)
detected
estimated
plants
(41.282
0.48;
10.06
0.18),
(53.81
0.25,
13.82
0.37
PN,
PL;
4.27
0.07),
(15.97
0.01;
0.48
0.003),
(63.24
0.35;
2.31
0.006),
(0.42
0.36
(0.71
0.03;
0.16
0.001),
(2.64
0.09;
0.12
0.004)
Method
found
be
rugged
robust.
results
all
validation
parameters
within
limits
according
ICH
guidelines.
Conclusion
is
fast,
precise,
economic,
specific
used
simultaneously
quantifiable
analysis
major
ingredients
(herbs)
formulations.
Язык: Английский
Polygenetic Analysis of Colchicum Species Using 18S rRNA Gene Sequence
Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 12, 2024
Colchicum
has
played
a
vital
role
in
the
field
of
medicine
due
to
its
inherent
properties,
with
importance
extending
from
past
present.
DNA
barcoding
is
an
effective
tool
for
identification
and
conservation
plant
species.
This
study
tested
application
18S
rRNA
gene
phylogenetic
construction
The
UPGMA
(unweighted
pair
group
method
arithmetic
mean)
tree
STRUCTURE
analysis
were
conducted
assess
consistency
results
33
specimens
one
outgroup
species,
utilizing
partial
gene.
showed
that
using
was
identifying
97.76%
sequences
being
successfully
determined.
contributes
species
by
illustrating
utility
construction,
underscoring
significance
advancing
our
understanding
genetics.
nucleotide
obtained
this
uploaded
barcode
life
data
system
(BOLD),
contributing
internationally
accessible
genetic
data.
Язык: Английский