Unprecedented and laborless polymer film of azorubin S for electrocatalytic sensing of nicotine in human serum and saliva

Electroanalysis, Год журнала: 2024, Номер 36(7)

Опубликована: Фев. 29, 2024

Abstract An accurate, disposable and cost‐effective determination, monitoring of nicotine in human bodily fluids such as serum saliva is significant due to the deleterious effects on humankind. In this paper, it was reported an electrocatalytic sensing platform for determination with poly azorubin s film modified pencil graphite electrode qualified by electroanalytical techniques cyclic voltammetry electrochemical impedance spectroscopy, electron beam based technique scanning microscopy, X‐ray including photoelectron spectroscopy energy dispersive spectroscopy. The developed exhibited a 410 % signal increase compared bare (280 current density over aPGE) detection improved charge transfer conductivity characteristics polymer film. oxidation peak at 700 mV employed good sensitivity , remarkable limit 89 nM, wide linear ranges 0.25–3 μM 5–100 μM. Furthermore, sensor showcases superb stability, selectivity accuracy real samples saliva.

Язык: Английский

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A novel perspective for estimating the passivation and energy storage characteristics in micro-mass coatings using CV, EIS, and EQCM techniques: Ultrahigh supercapacitor behaviors of Bismarck Brown R and Bismarck Brown Y polymer films

Journal of Energy Storage, Год журнала: 2025, Номер 115, С. 115985 - 115985

Опубликована: Фев. 27, 2025

Язык: Английский

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First DFT-supported point of care and novel electrochemical biosensing: Determination of yellow fever NS1 antibody in human plasma

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 269, С. 132169 - 132169

Опубликована: Май 8, 2024

Язык: Английский

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DNA-Coupled AuNPs@CuMOF for Sensitive Electrochemical Detection of Carcinoembryonic Antigen

ACS Applied Nano Materials, Год журнала: 2024, Номер 7(10), С. 11921 - 11930

Опубликована: Май 16, 2024

Detecting preinvasive tumors before the onset of advanced clinical symptoms represents a critical advancement in improving efficacy early medical interventions and reducing cancer-related mortality rates. Immunosensors have emerged as preferred choice for analyzing oncomarkers meeting ever-increasing demands diagnostics. Therefore, quest development highly specific sensitive immunosensors remains most sought-after to open new avenues personalized healthcare monitoring. Here, we report amplification-free nonlabeled DNA framework-coupled AuNPs@CuMOF ultrasensitive electrochemical detection carcinoembryonic antigen (CEA). Upon CEA concentration variation from 0.0001 200 ng mL–1, proposed biosensor led limit (LOD) 0.25 pg surpassing previously published biosensors that rely on methods aligns with those based amplification techniques. Furthermore, suggested immunosensor demonstrated auspiciously high specificity sensitivity detecting human serum comparable commercial ELISA within relative error falling between 6.25% 2.26%. The analytical approach, hinging synergy effect CuMOF's large surface area mechanical rigidity three-dimensional tetrahedron structured probes (3D TDNA), obviously broadens potential immunosensors, offering higher lower LOD. this work is not only an expansion CuMOF exploitation biosensing but also major milestone diverse biomarkers settings tumor diagnosis.

Язык: Английский

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Selective Amperometric Sensor for the Determination of Hydrazine at a Gold Nanoparticle Decorated Poly(Brilliant Blue) Modified Electrode

Analytical Letters, Год журнала: 2024, Номер unknown, С. 1 - 21

Опубликована: Фев. 26, 2024

There is a pressing requirement to synthesize stable electrode components that possess enhanced capabilities for creating electrochemical sensors, which are sensitive and discerning, swiftly detect dangerous noxious substances. A sensor has been developed in this study hydrazine (HY) oxidation, utilizing gold nanoparticles (AuNPs) poly(brilliant blue) (p(BB)) modifiers on the surface of pencil graphite (PGE). The features detecting were characterized by impedance spectroscopy (EIS), cyclic voltammetry (CV), scanning electron microscopy (SEM), energy dispersive X-ray (EDX), photoelectron (XPS). Additionally, when examined under optimal parameters using CV amperometry, proposed presents favorable analytical figures merit. AuNPs/p(BB)/PGE provides determination low levels water samples with detection limit 0.14 µM. wide linear range from 1.0 800 μM was obtained. findings indicate exhibits good stability, repeatability, reproducibility hydrazine. effectively used determine both mineral samples.

Язык: Английский

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Catalytic Competence of Gold Clusters Decorated Yellow 2 G Polymer Composite Film for Voltammetric Sensing of Dopamine and Nicotine in Biological Fluids

Synthetic Metals, Год журнала: 2024, Номер 309, С. 117765 - 117765

Опубликована: Окт. 9, 2024

Язык: Английский

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Batch-fabricated full glassy carbon fibers for real-time tonic and phasic dopamine detection

Frontiers in Bioengineering and Biotechnology, Год журнала: 2025, Номер 13

Опубликована: Фев. 28, 2025

Dopamine (DA) is a critical neurotransmitter that key in regulating motor functions, motivation, and reward-related behavior. Measuring both tonic (baseline, steady-state) phasic (rapid, burst-like) DA release essential for elucidating the mechanisms underlying neurological disorders, such as schizophrenia Parkinson’s disease, which are associated with dysregulated signaling. Carbon fiber microelectrodes (CFEs) considered gold standard measuring rapid changes due to their small size (5–10 µm), biocompatibility, flexibility, excellent electrochemical properties. However, achieving consistent results large-scale production of CFE arrays through manual fabrication poses significant challenges. We previously developed flexible glassy carbon (GC) microelectrode (MEAs) GC fiber-like MEAs (GCF MEAs) detection electrophysiology recording. also demonstrated feasibility fabricating MEA electrodes interconnects made from single homogeneous material, eliminating need metal interconnections addressing related concerns about electrical mechanical stability under prolonged cycling. Building on our prior experience, we now present double-etching microfabrication technique batch 10 μm × µm full fibers (fGCFs) fGCF arrays, composed entirely material. This process uses 2 µm-thick low-stress silicon nitride bottom insulator layer fGCFs. The effectiveness was validated scanning electron microscophy (SEM) energy dispersive X-ray spectroscopy (EDS) elemental analyses, confirmed uniformity Si₃N₄ insulation ensured overall integrity Using finite element analysis, optimized form factor achieve self-penetration up 3 mm into mouse striatum without additional support. characterization fGCFs high conductivity wide window. ability detect using fast scan cyclic voltammetry (FSCV) square wave (SWV), respectively, vitro vivo . With sensitivity detection, combined scalable self-supporting insertion capability, promising sensors offer enhanced practicality comprehensive monitoring.

Язык: Английский

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Hyamine 1622-I/I2-Incorporated Sensing Platform for Selective Measurement of Ascorbic Acid, Dopamine, Acetaminophen, Ibuprofen, and Tyrosine

Electrocatalysis, Год журнала: 2025, Номер unknown

Опубликована: Март 25, 2025

Язык: Английский

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Fabrication and electrochemical characterization of RGO-Y2O3: Eu3+/Li+ nanocomposite modified glassy carbon electrode for enhanced dopamine detection

Inorganic Chemistry Communications, Год журнала: 2025, Номер unknown, С. 114515 - 114515

Опубликована: Апрель 1, 2025

Язык: Английский

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A first in class disposable copolymer-graphite platform for electrocatalytic detection of dipicrylamine explosive in wastewater and soil samples

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113930 - 113930

Опубликована: Май 1, 2025

Язык: Английский

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