European Journal of Inorganic Chemistry,
Год журнала:
2024,
Номер
27(16)
Опубликована: Март 27, 2024
Abstract
This
study
explores
the
synthesis
and
diverse
properties
of
newly
synthesised
water‐soluble
cobalt
(II)
complexes
(
1
–
3
).
Analysis
through
various
methods,
including
Hirshfeld
surface
analysis,
reveals
distinctive
intermolecular
interactions,
particularly
robust
H‐bonding
contributions
to
crystal
packing.
2D
fingerprint
plots
provide
quantitative
insights
into
supramolecular
while
TGA‐DSC
analysis
elucidates
multi‐step
decomposition
processes,
mainly
involving
organic
moieties.
FT‐IR
SCXRD
confirm
structures
complexes.
Magnetic
susceptibility
measurements
show
paramagnetic
behaviour
in
all
FMO
calculations
expose
HOMO‐LUMO
gaps
charge
transfer
with
NBO
emphasizing
significance
chloride,
nitrogen,
oxygen
atoms
coordination.
In
addition,
pkCSM
profile
was
carried
out.
The
biological
reveal
potent
antibacterial
activity
for
2
against
Gram‐positive
Gram‐negative
bacteria.
Despite
lower
efficacy
compared
standard
antibiotics,
their
water
solubility
suggests
potential
human
pharmacological
applications.
terms
anti‐inflammatory
activity,
three
exhibit
concentration‐dependent
prevention
ovalbumin
denaturation,
being
most
effective.
Compound
,
despite
having
seven
carboxyl
groups,
exhibits
weakest
effect,
potentially
attributed
complex
formation
obscuring
these
groups.
Furthermore,
display
antioxidant
activities;
are
greater
than
BHT
ferric
thiocyanate
assay.
