Journal of Materials Chemistry B, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Novel multi-component supramolecular hydrogels with antibacterial and wound-healing-promoting functions were constructed by taking inspiration from the medication practice of Chinese herbs.
Язык: Английский
BMEMat, Год журнала: 2025, Номер unknown
Опубликована: Янв. 23, 2025
Abstract Chronic wounds are that difficult to heal or do not follow the normal healing process. These include pressure ulcers, diabetic venous and arterial incomplete ulcers. Unlike acute wounds, chronic often even heal. Its pathogenesis involves many factors; bacterial infection is main cause of wound. With increase in population aging, incidence has become a critical issue current medical health field. Management faced with problems long treatment time, difficulty, high cost, repeated attacks disability rate, which seriously threaten patients' ability take care themselves life heavy burden individuals, families society. Over past few years, development antibacterial hydrogels for infections received lot attention. Since only have mechanical properties hydrogels, biocompatibility adjustable functional structure, but also excellent properties, they may be an ideal dressing solve problem wound healing. This article introduces types their characteristics, challenges treating wounds. It classifies antimicrobial based on modes further discusses advancements smart along benefits obstacles using explores directions management.
Язык: Английский
Процитировано
3
Gels, Год журнала: 2025, Номер 11(2), С. 88 - 88
Опубликована: Янв. 23, 2025
There is ongoing research for biomedical applications of polyvinyl alcohol (PVA)-based hydrogels; however, the execution this has not yet been achieved at an appropriate level commercialization. Advanced perception necessary design and synthesis suitable materials, such as PVA-based hydrogel applications. Among polymers, drawn great interest in owing to their attractive potential with characteristics good biocompatibility, mechanical strength, apposite water content. By designing approach investigating structure, hydrogels can attain superb cytocompatibility, flexibility, antimicrobial activities, signifying that it a candidate tissue engineering regenerative medicine, drug delivery, wound dressing, contact lenses, other fields. In review, we highlight current progresses on explaining diverse usage across variety areas. We explain numerous techniques related phenomena based these materials. This review may stipulate wide reference future acumens materials extensive
Язык: Английский
Процитировано
3
Materials Today Bio, Год журнала: 2025, Номер 31, С. 101553 - 101553
Опубликована: Фев. 5, 2025
Wounds infected by bacteria pose a considerable challenge in the field of healthcare, particularly with increasing prevalence antibiotic-resistant pathogens. Traditional antibiotics often fail to achieve effective results due limited penetration, resistance development, and inadequate local concentration at wound sites. These limitations necessitate exploration alternative strategies that can overcome drawbacks conventional therapies. Nanomaterials have emerged as promising solution for tackling bacterial infections facilitating healing, thanks their distinct physicochemical characteristics multifunctional capabilities. This review highlights latest developments nanomaterials demonstrated enhanced antibacterial efficacy improved healing outcomes. The mechanisms are varied, including ion release, chemodynamic therapy, photothermal/photodynamic electrostatic interactions, delivery drugs, which not only combat but also address challenges posed biofilms antibiotic resistance. Furthermore, these create an optimal environment tissue regeneration, promoting faster closure. By leveraging unique attributes nanomaterials, there is significant opportunity revolutionize management wounds markedly improve patient
Язык: Английский
Процитировано
2
Heliyon, Год журнала: 2022, Номер 8(12), С. e12193 - e12193
Опубликована: Дек. 1, 2022
Язык: Английский
Процитировано
51
Acta Biomaterialia, Год журнала: 2023, Номер 166, С. 224 - 240
Опубликована: Май 18, 2023
Язык: Английский
Процитировано
42
International Journal of Biological Macromolecules, Год журнала: 2023, Номер 247, С. 125663 - 125663
Опубликована: Июль 2, 2023
Язык: Английский
Процитировано
32
International Journal of Biological Macromolecules, Год журнала: 2024, Номер unknown, С. 135482 - 135482
Опубликована: Сен. 1, 2024
Язык: Английский
Процитировано
18
Theranostics, Год журнала: 2024, Номер 14(11), С. 4198 - 4217
Опубликована: Янв. 1, 2024
The utilization of extracellular vesicles (EVs) in wound healing has been well-documented.However, the direct administration free EVs via subcutaneous injection at sites may result rapid dissipation bioactive components and diminished therapeutic efficacy.Functionalized hydrogels provide effective protection, as well ensure sustained release bioactivity during process, making them an ideal candidate material for delivering EVs.In this review, we introduce mechanisms by which accelerate healing, then elaborate on construction strategies engineered EVs.Subsequently, discuss synthesis application delivery systems to enhance complicated healing.Furthermore, face wounds, functionalized with specific microenvironment regulation capabilities, such antimicrobial, anti-inflammatory, immune regulation, used loading EVs, potential approaches addressing these challenges.Ultimately, deliberate future trajectories outlooks, offering a fresh viewpoint advancement artificial intelligence (AI)-energized materials 3D bio-printed multifunctional hydrogel-based dressings biomedical applications.
Язык: Английский
Процитировано
15
European Polymer Journal, Год журнала: 2024, Номер 216, С. 113260 - 113260
Опубликована: Июнь 24, 2024
Язык: Английский
Процитировано
14
Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 99, С. 105990 - 105990
Опубликована: Сен. 1, 2024
Язык: Английский
Процитировано
14