White matter alterations in Attention-Deficit/Hyperactivity Disorder (ADHD): a systematic review of 129 diffusion imaging studies with meta-analysis DOI Creative Commons
Valeria Parlatini, Takashi Itahashi, Ye-Ji Lee

и другие.

Molecular Psychiatry, Год журнала: 2023, Номер 28(10), С. 4098 - 4123

Опубликована: Июль 21, 2023

Abstract Aberrant anatomical brain connections in attention-deficit/hyperactivity disorder (ADHD) are reported inconsistently across diffusion weighted imaging (DWI) studies. Based on a pre-registered protocol (Prospero: CRD42021259192), we searched PubMed, Ovid, and Web of Knowledge until 26/03/2022 to conduct systematic review DWI We performed quality assessment based acquisition, preprocessing, analysis. Using signed differential mapping, meta-analyzed subset the retrieved studies amenable quantitative evidence synthesis, i.e., tract-based spatial statistics (TBSS) studies, individuals any age and, separately, children, adults, high-quality datasets. Finally, conducted meta-regressions test effect age, sex, medication-naïvety. included 129 (6739 ADHD participants 6476 controls), which 25 TBSS provided peak coordinates for case-control differences fractional anisotropy (FA)(32 datasets) 18 mean diffusivity (MD)(23 datasets). The highlighted white matter alterations (especially reduced FA) projection, commissural association pathways with ADHD, were associated symptom severity cognitive deficits. meta-analysis showed consistent FA splenium body corpus callosum, extending cingulum. Lower was related older did not survive pediatric meta-analysis. About 68% low quality, mainly due acquisitions non-isotropic voxels or lack motion correction; sensitivity analysis datasets yielded no significant results. Findings suggest prominent posterior interhemispheric subserving motor functions affected although these might be influenced by non-optimal acquisition parameters/preprocessing. Absence findings children may late development callosal fibers, enhance adulthood. Clinicodemographic methodological major barriers consistency comparability among should addressed future investigations.

Язык: Английский

Current state of knowledge on the prevalence of neurodevelopmental disorders in childhood according to the DSM-5: a systematic review in accordance with the PRISMA criteria DOI Creative Commons
Lorena Francés, Javier Quintero, Alberto Fernández

и другие.

Child and Adolescent Psychiatry and Mental Health, Год журнала: 2022, Номер 16(1)

Опубликована: Март 31, 2022

To interpret the current evidence on prevalence of neurodevelopmental disorders (NDDs) through a systematic review based both DSM-5 (2013) and PRISMA criteria.Empirical studies complying with guidelines were identified from four databases (PubMed, Scopus, Science Direct, ProQuest) systematically reviewed. In total, 17 articles selected for study.In scientific literature, there have been only few measuring NDDs according to criteria in people under 18 years old. The reported rates as follows: intellectual disability (ID), 0.63%; attention-deficit/hyperactivity disorder (ADHD), 5-11%; autism spectrum (ASD), 0.70-3%; specific learning (SLD), 3-10%; communication (CDs), 1-3.42%; motor (MDs), 0.76-17%. Although is extensive literature disorders, rarely assessed whole. All reviewed support idea that such can be considered chronic, heterogeneous, underdiagnosed conditions comorbidity multiple norm. Likewise, it estimated most studied ADHD, ASD SLD, remains stable over time consistent different cultures, ages, ethnicities sexes.The lead us conclude rate fluctuates globally between 4.70 88.50%; these variations depend methodological aspects estimation procedures, well sociocontextual phenomena. It also important consider found probably highly influenced by activity countries diagnosis training professionals who care children adolescents. Hence, need secondary intervention fields public health education minimize socioemotional consequences, prevent academic failure, reduce economic cost society.

Язык: Английский

Процитировано

184
Sex and gender in neurodevelopmental conditions DOI
Sven Bölte, Janina Neufeld, Peter B. Marschik

и другие.

Nature Reviews Neurology, Год журнала: 2023, Номер 19(3), С. 136 - 159

Опубликована: Фев. 6, 2023

Язык: Английский

Процитировано

129
The global prevalence of attention deficit hyperactivity disorder in children and adolescents: An umbrella review of meta-analyses DOI Creative Commons
Getinet Ayano, Sileshi Demelash,

Yitbarek Gizachew

и другие.

Journal of Affective Disorders, Год журнала: 2023, Номер 339, С. 860 - 866

Опубликована: Июль 24, 2023

Emerging epidemiological data suggest that hundreds of primary studies have examined the prevalence ADHD in children and adolescents dozens systematic view meta-analyses been conducted on subject. The purpose this umbrella review is to provide a robust synthesis evidence from these reviews meta-analyses.

Язык: Английский

Процитировано

109
Annual Research Review: Perspectives on progress in ADHD science – from characterization to cause DOI Creative Commons
Edmund Sonuga‐Barke, Stephen Becker, Sven Bölte

и другие.

Journal of Child Psychology and Psychiatry, Год журнала: 2022, Номер 64(4), С. 506 - 532

Опубликована: Окт. 11, 2022

The science of attention‐deficit/hyperactivity disorder (ADHD) is motivated by a translational goal – the discovery and exploitation knowledge about nature ADHD to benefit those individuals whose lives it affects. Over past fifty years, scientific research has made enormous strides in characterizing condition understanding its correlates causes. However, translation these insights into clinical benefits been limited. In this review, we provide selective focused survey field ADHD, providing our personal perspectives on what constitutes consensus, important new leads be highlighted, key outstanding questions addressed going forward. We cover two broad domains characterization and, risk factors, causal processes neuro‐biological pathways . Part one focuses developmental course co‐occurring characteristics conditions, functional impact living with including impairment, quality life, stigma. part two, explore genetic environmental influences putative mediating brain processes. final section, reflect future construct light cross‐cutting themes recent conceptual reformulations that cast traits as broader spectrum neurodivergence.

Язык: Английский

Процитировано

87
Incidence, prevalence, and global burden of ADHD from 1990 to 2019 across 204 countries: data, with critical re-analysis, from the Global Burden of Disease study DOI
Samuele Cortese,

Minjin Song,

Luís C. Farhat

и другие.

Molecular Psychiatry, Год журнала: 2023, Номер 28(11), С. 4823 - 4830

Опубликована: Сен. 8, 2023

Язык: Английский

Процитировано

86
Attention-deficit/hyperactivity disorder DOI
Stephen V. Faraone, Mark A. Bellgrove, Isabell Brikell

и другие.

Nature Reviews Disease Primers, Год журнала: 2024, Номер 10(1)

Опубликована: Фев. 22, 2024

Язык: Английский

Процитировано

84
Application of data fusion for automated detection of children with developmental and mental disorders: A systematic review of the last decade DOI Creative Commons
Smith K. Khare, Sonja March, Prabal Datta Barua

и другие.

Information Fusion, Год журнала: 2023, Номер 99, С. 101898 - 101898

Опубликована: Июнь 25, 2023

Mental health is a basic need for sustainable and developing society. The prevalence financial burden of mental illness have increased globally, especially in response to community worldwide pandemic events. Children suffering from such disorders find it difficult cope with educational, occupational, personal, societal developments, treatments are not accessible all. Advancements technology resulted much research examining the use artificial intelligence detect or identify characteristics illness. Therefore, this paper presents systematic review nine developmental (Autism spectrum disorder, Attention deficit hyperactivity Schizophrenia, Anxiety, Depression, Dyslexia, Post-traumatic stress Tourette syndrome, Obsessive-compulsive disorder) prominent children adolescents. Our focuses on automated detection these using physiological signals. This also detailed discussion signal analysis, feature engineering, decision-making their advantages, future directions challenges papers published children. We presented details dataset description, validation techniques, features extracted models. present open questions availability, uncertainty, explainability, hardware implementation resources analysis machine deep learning Finally, main findings study conclusion section.

Язык: Английский

Процитировано

79
Immersive virtual reality for improving cognitive deficits in children with ADHD: a systematic review and meta-analysis DOI Creative Commons

Niamh Corrigan,

Costina Ruxandra Păsărelu, Alexandra Voinescu

и другие.

Virtual Reality, Год журнала: 2023, Номер 27(4), С. 3545 - 3564

Опубликована: Фев. 18, 2023

Abstract Virtual reality (VR) shows great potential in treating and managing various mental health conditions. This includes using VR for training or rehabilitation purposes. For example, is being used to improve cognitive functioning (e.g. attention) among children with attention/deficit-hyperactivity disorder (ADHD). The aim of the current review meta-analysis evaluate effectiveness immersive VR-based interventions improving deficits ADHD, investigate moderators effect size assess treatment adherence safety. included seven randomised controlled trials (RCTs) ADHD comparing controls waiting list, medication, psychotherapy, training, neurofeedback hemoencephalographic biofeedback) on measures cognition. Results indicated large sizes favour outcomes global functioning, attention, memory. Neither intervention length nor participant age moderated functioning. Control group type (active vs passive control group), diagnostic status (formal vs. informal) novelty technology were not significant Treatment was similar across groups there no adverse effects. should be cautiously interpreted given poor quality studies small sample.

Язык: Английский

Процитировано

55
ADHD Prevalence Among U.S. Children and Adolescents in 2022: Diagnosis, Severity, Co-Occurring Disorders, and Treatment DOI Creative Commons
Melissa L. Danielson, Angelika H. Claussen, Rebecca H. Bitsko

и другие.

Journal of Clinical Child & Adolescent Psychology, Год журнала: 2024, Номер 53(3), С. 343 - 360

Опубликована: Май 3, 2024

To provide updated national prevalence estimates of diagnosed attention-deficit/hyperactivity disorder (ADHD), ADHD severity, co-occurring disorders, and receipt medication behavioral treatment among U.S. children adolescents by demographic clinical subgroups using data from the 2022 National Survey Children's Health (NSCH).

Язык: Английский

Процитировано

54
ADHD Pharmacotherapy and Mortality in Individuals With ADHD DOI
Lin Li, Nanbo Zhu, Le Zhang

и другие.

JAMA, Год журнала: 2024, Номер 331(10), С. 850 - 850

Опубликована: Март 12, 2024

Importance Attention-deficit/hyperactivity disorder (ADHD) is associated with increased risks of adverse health outcomes including premature death, but it unclear whether ADHD pharmacotherapy influences the mortality risk. Objective To investigate initiation was reduced risk in individuals ADHD. Design, Setting, and Participants In an observational nationwide cohort study Sweden applying target trial emulation framework, we identified aged 6 through 64 years incident diagnosis from 2007 2018 no medication dispensation prior to diagnosis. Follow-up started until emigration, 2 after diagnosis, or December 31, 2020, whichever came first. Exposures defined as dispensing within 3 months Main Outcomes Measures We assessed all-cause well natural-cause (eg, physical conditions) unnatural-cause unintentional injuries, suicide, accidental poisonings). Results Of 148 578 (61 356 females [41.3%]), 84 204 (56.7%) initiated medication. The median age at 17.4 (IQR, 11.6-29.1 years). 2-year lower treatment strategy group (39.1 per 10 000 individuals) than noninitiation (48.1 individuals), a difference −8.9 (95% CI, −17.3 −0.6). significantly rate (hazard ratio [HR], 0.79; 95% 0.70 0.88) (2-year risk, 25.9 vs 33.3 individuals; difference, −7.4 −14.2 −0.5; HR, 0.75; 0.66 0.86), not 13.1 14.7 −1.6 −6.4 3.2; 0.86; 0.71 1.05). Conclusions Relevance Among diagnosed ADHD, mortality, particularly for death due unnatural causes.

Язык: Английский

Процитировано

53