Neural mechanisms and temporal dynamics of performance monitoring

Trends in Cognitive Sciences, Год журнала: 2014, Номер 18(5), С. 259 - 267

Опубликована: Март 22, 2014

Язык: Английский

---

Arithmetic and local circuitry underlying dopamine prediction errors

Nature, Год журнала: 2015, Номер 525(7568), С. 243 - 246

Опубликована: Авг. 31, 2015

Язык: Английский

---

Revisiting the Role of Infralimbic Cortex in Fear Extinction with Optogenetics

Journal of Neuroscience, Год журнала: 2015, Номер 35(8), С. 3607 - 3615

Опубликована: Фев. 25, 2015

Previous rodent studies have implicated the infralimbic (IL) subregion of medial prefrontal cortex in extinction auditory fear conditioning. However, these used pharmacological inactivation or electrical stimulation techniques, which lack temporal precision and neuronal specificity. Here, we an optogenetic approach to either activate (with channelrhodopsin) silence halorhodopsin) glutamatergic IL neurons during conditioned tones delivered one two phases: training retrieval. Activating reduced expression strengthened memory following day. Silencing had no effect on within-session extinction, but impaired retrieval day, indicating that activity is necessary for formation memory. Surprisingly, however, silencing optogenetically pharmacologically 1 day week effect. Our findings suggest likely facilitates storage target structures, contrary current models, does not appear be

Язык: Английский

---

Nucleus Accumbens Subnuclei Regulate Motivated Behavior via Direct Inhibition and Disinhibition of VTA Dopamine Subpopulations

Neuron, Год журнала: 2018, Номер 97(2), С. 434 - 449.e4

Опубликована: Янв. 1, 2018

Язык: Английский

---

Dopamine Prediction Errors in Reward Learning and Addiction: From Theory to Neural Circuitry

Neuron, Год журнала: 2015, Номер 88(2), С. 247 - 263

Опубликована: Окт. 1, 2015

Язык: Английский

---