The Raphe Dopamine System: Roles in Salience Encoding, Memory Expression, and Addiction

Trends in Neurosciences, Год журнала: 2021, Номер 44(5), С. 366 - 377

Опубликована: Фев. 8, 2021

Язык: Английский

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Basal forebrain mediates prosocial behavior via disinhibition of midbrain dopamine neurons

Proceedings of the National Academy of Sciences, Год журнала: 2021, Номер 118(7)

Опубликована: Фев. 9, 2021

Significance The basal forebrain (BF) is traditionally recognized as a brain structure crucial for arousal, attention, learning, and memory. Here, we discovered causal role of the BF in control prosocial behavior, which fundamental our daily life. We showed mice that somatostatin-expressing inhibitory neurons predominantly target GABA disinhibit dopamine ventral tegmental area thereby increase release nucleus accumbens. This disinhibitory circuitry played an essential promoting social interaction behavior. Our findings identify previously unknown function behavior regulation suggest potential therapeutic deficits commonly observed major neuropsychiatric disorders.

Язык: Английский

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A corticoamygdalar pathway controls reward devaluation and depression using dynamic inhibition code

Neuron, Год журнала: 2023, Номер 111(23), С. 3837 - 3853.e5

Опубликована: Сен. 20, 2023

Язык: Английский

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Past, Present, and Future of Tools for Dopamine Detection

Neuroscience, Год журнала: 2023, Номер 525, С. 13 - 25

Опубликована: Июль 5, 2023

Язык: Английский

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The dorsal raphe nucleus in the control of energy balance

Trends in Neurosciences, Год журнала: 2021, Номер 44(12), С. 946 - 960

Опубликована: Окт. 18, 2021

Язык: Английский

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