Obesity, dyslipidemia, and cardiovascular disease: A joint expert review from the Obesity Medicine Association and the National Lipid Association 2024
Journal of clinical lipidology,
Год журнала:
2024,
Номер
18(3), С. e320 - e350
Опубликована: Апрель 24, 2024
BACKGROUNDThis
joint
expert
review
by
the
Obesity
Medicine
Association
(OMA)
and
National
Lipid
(NLA)
provides
clinicians
an
overview
of
pathophysiologic
clinical
considerations
regarding
obesity,
dyslipidemia,
cardiovascular
disease
(CVD)
risk.METHODSThis
is
based
upon
scientific
evidence,
perspectives
authors,
peer
OMA
NLA
leadership.RESULTSAmong
individuals
with
adipose
tissue
may
store
over
50%
total
body
free
cholesterol.
Triglycerides
represent
up
to
99%
lipid
species
in
tissue.
The
potential
for
expansion
accounts
greatest
weight
variance
among
most
individuals,
percent
fat
ranging
from
less
than
5%
60%.
While
population
studies
suggest
a
modest
increase
blood
low-density
lipoprotein
cholesterol
(LDL-C)
levels
excess
adiposity,
adiposopathic
dyslipidemia
pattern
often
described
adiposity
includes
elevated
triglycerides,
reduced
high
density
(HDL-C),
increased
non-HDL-C,
apolipoprotein
B,
LDL
particle
concentration,
small,
dense
particles.CONCLUSIONSObesity
increases
CVD
risk,
at
least
partially
due
promotion
adiposopathic,
atherogenic
profile.
also
worsens
other
cardiometabolic
risk
factors.
Among
patients
interventions
that
reduce
improve
outcomes
are
generally
associated
improved
levels.
Given
improvement
LDL-C
reduction
overweight
or
early
treat
both
(LDL-C
and/or
non-HDL-C)
priorities
reducing
CVD.
This
risk.
leadership.
particles.
Язык: Английский
Obesity, dyslipidemia, and cardiovascular disease: A joint expert review from the Obesity Medicine Association and the National Lipid Association 2024
Obesity Pillars,
Год журнала:
2024,
Номер
10, С. 100108 - 100108
Опубликована: Март 12, 2024
This
joint
expert
review
by
the
Obesity
Medicine
Association
(OMA)
and
National
Lipid
(NLA)
provides
clinicians
an
overview
of
pathophysiologic
clinical
considerations
regarding
obesity,
dyslipidemia,
cardiovascular
disease
(CVD)
risk.
is
based
upon
scientific
evidence,
perspectives
authors,
peer
OMA
NLA
leadership.
Among
individuals
with
adipose
tissue
may
store
over
50%
total
body
free
cholesterol.
Triglycerides
represent
up
to
99%
lipid
species
in
tissue.
The
potential
for
expansion
accounts
greatest
weight
variance
among
most
individuals,
percent
fat
ranging
from
less
than
5%
60%.
While
population
studies
suggest
a
modest
increase
blood
low-density
lipoprotein
cholesterol
(LDL-C)
levels
excess
adiposity,
adiposopathic
dyslipidemia
pattern
often
described
adiposity
includes
elevated
triglycerides,
reduced
high
density
(HDL-C),
increased
non-HDL-C,
apolipoprotein
B,
LDL
particle
concentration,
small,
dense
particles.
increases
CVD
risk,
at
least
partially
due
promotion
adiposopathic,
atherogenic
profile.
also
worsens
other
cardiometabolic
risk
factors.
patients
interventions
that
reduce
improve
outcomes
are
generally
associated
improved
levels.
Given
improvement
LDL-C
reduction
overweight
or
early
treat
both
(LDL-C
and/or
non-HDL-C)
priorities
reducing
CVD.
Язык: Английский
Sex-Specific Factors Influencing Obesity in Women: Bridging the Gap Between Science and Clinical Practice
Circulation Research,
Год журнала:
2025,
Номер
136(6), С. 594 - 605
Опубликована: Март 13, 2025
Obesity
in
women
is
a
significant
public
health
issue
with
serious
implications
for
cardiovascular-kidney-metabolic
syndrome
and
cardiovascular
disease.
This
complex
challenge
influenced
by
physiological,
hormonal,
socioeconomic,
cultural
factors.
Women
face
unique
weight
management
challenges
due
to
hormonal
changes
during
pregnancy,
perimenopause,
menopause,
which
affect
fat
distribution
increase
risk.
Current
clinical
guidelines
often
overlook
these
sex-specific
factors,
potentially
limiting
the
effectiveness
of
obesity
strategies
women.
review
explores
aspects
obesity’s
pathophysiology,
epidemiological
trends,
associated
comorbidities,
focusing
on
metabolic
complications.
synthesizes
literature
women,
emphasizing
factors
influencing
its
development
progression.
It
examines
limitations
body
mass
index
as
an
measure
alternative
classification
methods.
Additionally
it
investigates
relationship
between
comorbidities
such
diabetes,
hypertension,
dyslipidemia,
focus
postmenopausal
linked
increased
risks
Hormonal
fluctuations
throughout
life
contribute
gain
patterns
specific
increasing
disease
Effective
must
account
variations.
Postmenopausal
are
particularly
affected
obesity-related
Lifestyle
interventions,
pharmacotherapy,
bariatric
surgery
have
shown
efficacy
management,
though
success
rates
vary.
Addressing
requires
comprehensive
approach
that
considers
physiological
life-stage
challenges,
sociocultural
barriers.
Integrating
precision
medicine
emerging
therapies
offers
potential
more
personalized
effective
interventions.
Personalized
consider
women’s
biological
can
enhance
improve
outcomes.
Future
research
practice
should
developing
tailored
address
vulnerabilities
validating
interventions
Язык: Английский
The AHA/ACC/HFSA 2022 Heart Failure Guidelines: Changing the Focus to Heart Failure Prevention
American Journal of Preventive Cardiology,
Год журнала:
2023,
Номер
15, С. 100527 - 100527
Опубликована: Июль 30, 2023
The
prevalence
of
heart
failure
(HF)
in
the
United
States
(U.S.)
is
estimated
at
over
6
million
adults,
with
incidence
continuing
to
increase.
A
large
proportion
U.S.
population
also
risk
HF
due
high
established
factors,
such
as
hypertension,
diabetes,
and
obesity.
Many
individuals
have
multiple
placing
them
even
higher
risk.
In
addition,
these
factors
disproportionately
impact
various
racial
ethnic
groups.
Recognizing
rising
health
economic
burden
U.S.,
2022
American
Heart
Association
/
College
Cardiology
Failure
Society
America
(AHA/ACC/HFSA)
Guideline
placed
a
strong
emphasis
on
prevention
HF.
purpose
this
review
highlight
role
both
primary
secondary
HF,
outlined
by
recent
guideline,
address
preventive
cardiology
community
reducing
at-risk
individuals.
Язык: Английский
An updated study protocol for a real-life digital 12-month weight management program, the Healthy Weight Coaching
Annals of Medicine,
Год журнала:
2024,
Номер
56(1)
Опубликована: Сен. 4, 2024
Obesity
is
an
important
health
concern
that
poses
many
public
challenges.
Evidence-based
treatment
modalities,
capable
of
cost-effectively
reaching
large
patient
groups
are
needed.
In
this
paper,
we
present
the
design
and
methods
updated
national,
12-month,
digital
weight
management
program,
Healthy
Weight
Coaching
(HWC).
The
major
updates,
as
compared
to
previous
version,
related
theoretical
background
obesity
BMI
cut-offs.
HWC
available,
based
on
physicians'
referrals,
adult
Finnish
citizens
with
≥30
kg/m
Язык: Английский
Relationship between dietary knowledge, food preference, and long-short term health status among Chinese adults.
PubMed,
Год журнала:
2024,
Номер
33(2), С. 213 - 227
Опубликована: Июнь 1, 2024
In
recent
years,
with
the
improvement
of
people's
living
standards
and
changes
in
dietary
patterns,
knowledge
food
preference
have
been
playing
an
increasingly
crucial
role
health.
The
aim
our
study
was
to
examine
relationship
between
knowledge,
preference,
long-short
term
health
status
among
Chinese
adults
aged
18-70.
Язык: Английский
Universal Prior Authorization Template for glucagon like peptide-1 based anti-obesity medications: An Obesity Medicine Association proposal
Obesity Pillars,
Год журнала:
2023,
Номер
8, С. 100079 - 100079
Опубликована: Авг. 2, 2023
Язык: Английский
Fruit and vegetable consumption: Study involving Portuguese and French consumers
Open Agriculture,
Год журнала:
2024,
Номер
9(1)
Опубликована: Янв. 1, 2024
Abstract
The
regular
consumption
of
vegetables
and
fruits
has
been
indicated
as
part
a
healthy
diet.
They
are
considered
foods
because
they
sources
vitamins,
minerals,
fibre.
Adequate
intake
these
can
reduce
the
risk
certain
chronic
diseases,
like
cardiovascular
disease,
diabetes,
obesity,
various
types
cancer.
objective
present
study
was
to
determine
habits
in
two
different
countries,
Portugal
France.
For
this
descriptive
study,
it
used
questionnaire
survey,
applied
individuals
over
18
years
old
carried
out
through
internet,
being
disseminated
on
social
networks
by
email.
sample
constituted
640
participants
(257
from
383
France).
Statistical
tools
were
for
treatment
data,
T
-Test
chi-square
test
utilised
compare
results
between
Portuguese
French
consumers.
showed
that
eat
more
often
than
French.
equally
but
fruit
per
week
average
Portuguese.
soup
much
regularly
prefer
with
cut
pieces,
unlike
which
grounded
vegetables.
global
is
low
both
countries
should
be
increased,
most
especially
Portugal,
where
lower.
In
conclusion,
despite
some
differences
found
across
consumers
according
country,
still
below
recommendations
World
Health
Organisation,
therefore,
actions
necessary
incentivise
higher
lifestyle.
Язык: Английский
Appetite Suppressing Activity of Rumex Usambarensis Leaf and Stem Aqueous Extract in Wistar Albino Female Rats: an in vivo Experimental Study
Journal of Experimental Pharmacology,
Год журнала:
2024,
Номер
Volume 16, С. 201 - 209
Опубликована: Май 1, 2024
Background:
The
burden
of
obesity
and
overweight
associated
morbidity
mortality
is
increasing
in
epidemic
proportions
worldwide.
Suppression
appetite
one
the
mechanisms
that
has
been
shown
to
reduce
weight.
Most
drugs
on
market
currently
for
suppression
are
not
readily
available
or
affordable
resource-limited
settings.
Additionally,
previous
studies
have
most
these
with
significant
adverse
effects,
which
demonstrates
a
need
alternative
complementary
options
suppression.
In
Uganda,
herdsmen
commonly
chew
raw
stems
leaves
Rumex
usambarensis,
wild
shrub,
this
believed
hunger.
This
study
aimed
at
determining
effect
usambarensis
aqueous
extract
food
intake
as
measure
Wistar
albino
rats.
Methods:
was
carried
out
two
phases:
fattening
phase
treatment
phase.
Female
rats
were
fed
high-fat
diet
49
days.
fattened
animals
then
randomly
separated
into
4
groups,
received
1
mL
distilled
water
(negative
control),
500
mg/kg
body
weight
1000
20
topiramate
(positive
respectively.
Food
measured
every
day,
weights
taken
days
group.
Results:
significantly
reduced
compared
control
group
both
doses:
500mg/kg
dose
(Mean
difference,
MD
=
17.2,
p
<
0.001)
1000mg/kg
(MD
25.9,
0.001).
doses
showed
reduction
intake:
16.1,
37.3,
There
strong
correlation
between
(r
0.744,
0.009),
strongest
association
observed
0.906,
Conclusion:
suppressing
effects
female
could
be
an
efficacious
medicine
management
overweight,
other
related
disorders.
Keywords:
appetite,
weight,
obesity,
dammer
Язык: Английский