Importance of Pattern Standard Deviation of Humphrey 10-2 Visual Field to Evaluate Central Visual Function in Patients with Early-Stage Glaucoma DOI Open Access

Hee Jong Shin,

Si Eun Oh,

Chan Kee Park

и другие.

Journal of Clinical Medicine, Год журнала: 2023, Номер 12(15), С. 5091 - 5091

Опубликована: Авг. 2, 2023

To explore various parameters that can evaluate the central visual impairment in patients with early-stage glaucoma, we included into a study impairments an MD value greater than −6.0 dB on 24-2 VF test. A possible association between structural acquired by OCT and functional of PERG was determined. total 70 eyes suspected glaucoma or NTG underwent VF, OCT, examinations. The were classified two groups according to We used Pearson correlation analysis relationships GCIPL thickness/RNFL thickness parameters, such as perimetry. Linear regression analyses conducted significant factors affecting PSD 10-2. In low group, P50 amplitude presented correlations (r = 0.346, p 0.048) thickness. high it found only 10-2 uniquely borderline −0.327, 0.055), no other parameter showed correlation. Univariate multivariate revealed significantly associated (p < 0.001 0.013, respectively). Among demonstrated statistically structure-function glaucoma.

Язык: Английский

Predicting visual field global and local parameters from OCT measurements using explainable machine learning DOI Creative Commons
Md. Mahmudul Hasan, Jack Phu, Henrietta Wang

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Фев. 16, 2025

Abstract Glaucoma is characterised by progressive vision loss due to retinal ganglion cell deterioration, leading gradual visual field (VF) impairment. The standard VF test may be impractical in some cases, where optical coherence tomography (OCT) can offer predictive insights into for multimodal diagnoses. However, predicting measures from OCT data remains challenging. To address this, five regression models were developed predict OCT, Shapley Additive exPlanations (SHAP) analysis was performed interpretability, and a clinical software tool called Predictor developed. evaluate the models, total of 268 glaucomatous eyes (86 early, 72 moderate, 110 advanced) 226 normal included. machine learning outperformed recent OCT-based prediction deep studies, with correlation coefficients 0.76, 0.80 0.76 mean deviation, index pattern respectively. Introducing pointwise normalisation step-size concept, absolute error 2.51 dB obtained sensitivity prediction, grayscale model yielded structural similarity 77%. SHAP-based provided critical most relevant features glaucoma diagnosis, showing promise assisting eye care practitioners through an explainable AI tool.

Язык: Английский

Процитировано

4
Current perspectives in tackling glaucoma blindness DOI Creative Commons

Shibal Bhartiya,

Parul Ichhpujani, Meenakshi Wadhwani

и другие.

Indian Journal of Ophthalmology, Год журнала: 2025, Номер 73(Suppl 2), С. S189 - S196

Опубликована: Фев. 21, 2025

As a major reason for irreversible vision loss, glaucoma is significant public health concern. Its multifactorial nature demands nuanced understanding of its pathophysiology, risk factors, and management. An understanding, continuous refinement, diagnostic therapeutic modalities, including pharmacological interventions, novel methods drug delivery, surgical techniques (including minimally invasive surgeries) are critical. The advent personalized medicine, genetic profiling, innovative biomarkers identifying susceptible individuals tailoring treatment strategies may help prevent blindness improve patient outcomes. Evaluation the impact lifestyle modifications holistic approaches integration telemedicine artificial intelligence in management revolutionize current practice. In addressing global challenge blindness, this narrative review highlights ongoing initiatives, policies, community-based interventions. This includes raising awareness, enhancing early detection programs, access to care, particularly underserved populations.

Язык: Английский

Процитировано

1
Visual field testing in glaucoma using the Swedish Interactive Threshold Algorithm DOI Creative Commons
Jeremy Tan, Jithin Yohannan, Pradeep Y. Ramulu

и другие.

Survey of Ophthalmology, Год журнала: 2024, Номер unknown

Опубликована: Сен. 1, 2024

Язык: Английский

Процитировано

6
Fast Progressors in Glaucoma DOI Creative Commons
Aidan Jackson, Keith R. Martin, Michael Coote

и другие.

Ophthalmology, Год журнала: 2023, Номер 130(5), С. 462 - 468

Опубликована: Янв. 21, 2023

Язык: Английский

Процитировано

13
The Frontloading Fields Study: The Impact of False Positives and Seeding Point Errors on Visual Field Reliability When Using SITA-Faster DOI Creative Commons
Jack Phu, Michael Kalloniatis

Translational Vision Science & Technology, Год журнала: 2022, Номер 11(2), С. 20 - 20

Опубликована: Фев. 10, 2022

The purpose of this study was to evaluate the impact two conventional reliability criteria (false positives [FPs] and seeding point errors [SPEs]) concurrent effect low sensitivity points (≤19 dB) on intrasession SITA-Faster visual field (VF) result correlations.There were 2320 VF results from 1160 eyes healthy, glaucoma suspects, subjects with that separated into "both reliable" or "reliable-unreliable" pairs. (mean deviation pointwise sensitivity) analyzed against spectrum FP rates SPE, without censorship ≤19 dB. Segmental linear regression used identify critical where significantly different between tests due levels.There a significant, but small (0.09 dB per 1% exceeding 12%) increase in mean deviation, an number showing >3 (0.25-0.28 locations 12%). SPEs almost exclusively related decrease at primary did not significant differences other indices. Censoring improved correlation reliable unreliable results.Current for judging (FP rate >15% SPE) can lead data being erroneously excluded, as many do show compared those deemed "reliable." improves correlations results.We provide guidelines assessing FP, interpretation.

Язык: Английский

Процитировано

15
Simple reaction time to visual and auditory stimulation in glaucoma DOI
Quentin Lenoble, Ruthly François,

Duault Matthieu

и другие.

European Journal of Ophthalmology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 3, 2025

Background/Objectives Glaucoma can impact the ability to perform daily life activities such as driving. In tasks, reaction time is critical detect hazards. Understanding modalities that affect response times thus essential for clinical care. Subjects/Method Simple in which participants respond fast possible a stimulus, constitute basic measure of processing speed. visual and auditory stimuli were compared assess whether glaucomatous patients exhibit general slowing execution speed or specific signals.Twenty with primary open angle glaucoma, 16 age-matched normally sighted controls young instructed press space bar computer soon they detected (a 3° black ring) an 440 Hz sound) signal. The two tested independent blocks 63 trials. Results Participants glaucoma significantly slower than older modality but not modality, simple did differ between groups. Conclusion This study suggests reduced cannot be attributed motor attentional impairments probably results from delay transmission information.

Язык: Английский

Процитировано

0
Evaluation of visual function within the central 10 degrees using IMOvifa™ 24plus (1-2) DOI Creative Commons
Y Takagi,

Ryo ASANO,

Kana Yamashita

и другие.

PLoS ONE, Год журнала: 2025, Номер 20(5), С. e0323630 - e0323630

Опубликована: Май 12, 2025

Purpose The IMOvifa™ perimeter with a 24plus (1-2) testing mode has additional measurement points within the central 10 degrees, which may help evaluate visual field this area. Here, we comparatively evaluated and HFA 10-2 for first time. Methods We included 30 patients (48 eyes) who underwent 24-2 Swedish Interactive Threshold Algorithm Standard Ambient Zippy Estimated tests on same day six months. used Spearman’s rank correlation coefficient to analyze mean deviation (MD) pattern standard (PSD) between IMOvifa™. 10-degree was divided into four sectors, concordance of defects using kappa analysis. Additionally, all sectors showing sensitivity 0 dB were assessed presence agreement residual in (1-2). Results MD (0.843/0.804) PSD (0.852/0.763) correlated strongly those 10-2. Regarding ability detect κ = 0.715 (0.611,0.819) 0.754 (0.654,0.854) 24-2, respectively. In evaluation field, detected function 100% cases where indicated function. Conclusion have higher certain areas compared also However, is difficult substitute test, as test necessary evaluating degrees.

Язык: Английский

Процитировано

0
Central Visual Field Testing in Early Glaucoma DOI Open Access
Darrell WuDunn, Hana L. Takusagawa, Jullia A. Rosdahl

и другие.

Ophthalmology, Год журнала: 2023, Номер 131(2), С. 240 - 248

Опубликована: Дек. 8, 2023

Язык: Английский

Процитировано

7
Evaluation of the Consistency of Glaucomatous Visual Field Defects Using a Clustered SITA-Faster Protocol DOI Open Access
Jeremy Tan, Jack Phu,

Denise Go

и другие.

Ophthalmology, Год журнала: 2023, Номер 130(11), С. 1138 - 1148

Опубликована: Июнь 28, 2023

Язык: Английский

Процитировано

6
Which glaucoma patients benefit from 10-2 visual field testing? Proposing the functional vulnerability zone framework DOI Creative Commons
Jack Phu, Daniel Rafla, Michael Kalloniatis

и другие.

Clinical and Experimental Optometry, Год журнала: 2023, Номер unknown, С. 1 - 13

Опубликована: Дек. 6, 2023

Clinical relevance A method for determining 10-2 deployment in glaucoma with the goal of detecting additional visual field sensitivity purpose functional monitoring is proposed.

Язык: Английский

Процитировано

6