ACS Applied Materials & Interfaces,
Год журнала:
2023,
Номер
15(35), С. 41287 - 41298
Опубликована: Авг. 26, 2023
Bacterial
infections
severely
threaten
human
health;
therefore,
it
is
important
to
endow
the
matrix
for
tissue
engineering
with
antibacterial
efficiency.
The
loading
of
drugs
on
nanomaterials
provides
an
efficient
strategy
realize
synergistic
By
depositing
various
metal–organic
frameworks,
such
as
UIO-66,
onto
konjac
glucomannan
(KGM),
composite
hydrogels
(KGM/UIO-66)
were
created.
These
used
drug
carriers,
enabling
development
high
capacities
(e.g.,
maximum
amount
pterostilbene
KGM/UIO-66
reached
0.157
mg/mg)
and
sustained
release.
resulting
KGM/UIO-66/pterostilbene
hydrogel
exhibited
a
three-dimensional
porous
structure,
excellent
biocompatibility,
efficiency,
anti-inflammatory
activity.
It
effectively
protected
cells
from
bacterial
attacks
while
ensuring
cell
adhesion
proliferation,
demonstrating
great
potential
substrate
biomedical
applications,
including
regenerative
medicine.
Abstract
The
global
pandemic
and
excessive
use
of
antibiotics
have
raised
concerns
about
environmental
health,
efforts
are
being
made
to
develop
alternative
bactericidal
agents
for
disinfection.
Metal‐based
nanomaterials
their
derivatives
emerged
as
promising
candidates
antibacterial
due
broad‐spectrum
activity,
friendliness,
excellent
biocompatibility.
However,
the
reported
mechanisms
these
materials
complex
lack
a
comprehensive
understanding
from
coherent
perspective.
To
address
this
issue,
new
perspective
is
proposed
in
review
demonstrate
toxic
activities
metal‐based
terms
energy
conversion
electron
transfer.
First,
antimicrobial
different
discussed,
advanced
research
progresses
summarized.
Then,
biological
intelligence
applications
materials,
such
biomedical
implants,
stimuli‐responsive
electronic
devices,
monitoring,
concluded
based
on
trappable
electrical
signals
Finally,
current
improvement
strategies,
future
challenges,
possible
resolutions
outlined
provide
insights
into
behaviors
offer
valuable
inspiration
instructional
suggestions
building
intelligent
health.
Contact
lenses
(CLs)
are
prone
to
adhesion
and
invasion
by
pollutants
pathogenic
bacteria,
leading
infection
inflammatory
diseases.
However,
the
functionalization
of
CL
(biological
functions
such
as
anti-fouling,
antibacterial,
anti-inflammatory)
maintaining
its
transparency
still
face
great
challenges.
In
this
work,
a
member
MXenes
family,
vanadium
carbide
(V
2
C)
is
modified
onto
via
water
transfer
printing
method
after
formation
tightly
arranged
uniform
film
at
surface
under
action
Marangoni
effect.
The
coating
interface
stable
owing
electrostatic
forces.
V
C-modified
C@CL)
maintains
optical
clarity
while
providing
good
biocompatibility,
strong
antioxidant
properties,
anti-inflammatory
activities.
vitro
antibacterial
experiments
indicate
that
C@CL
shows
excellent
performance
in
bacterial
anti-adhesion,
sterilization,
anti-biofilm
formation.
Last,
displays
notable
advantages
bacteria
elimination
inflammation
removal
infectious
keratitis
treatment.
ACS Applied Materials & Interfaces,
Год журнала:
2023,
Номер
15(43), С. 50155 - 50165
Опубликована: Окт. 18, 2023
In
a
novel
approach
that
capitalized
on
the
differential
solubility
product
(Ksp)
of
ZnSe
and
Ag2Se,
unique
ZnSe/Ag2Se
binary
heterostructure
was
efficiently
synthesized
in
situ.
exhibited
excellent
antimicrobial
efficiency
under
visible
light.
Incorporating
Ag2Se
into
significantly
enhanced
photoelectric
performance
catalyst,
greatly
accelerating
separation
photogenerated
electrons
system.
Active
species
removal
experiments
determined
·O2-
H2O2
played
crucial
roles
photocatalytic
antibacterial
efficiency.
Further
investigation
levels
cellular
membrane
peroxidation,
bacterial
morphology,
intracellular
contents
concentration
revealed
during
process,
reactive
oxygen
initially
oxidize
phospholipids
cell
membrane,
leading
to
damage
external
structure
leakage
contents,
ultimately
resulting
bacteria
inactivation.
The
process
fundamentally
deviates
from
conventional
methods,
offering
new
insights
efficient
disinfection
mechanisms.
